The paper proposes an inter-laboratory playbook for calibrating widely available standards against scarce reference material issued by a global authority such as WHO. The goal is to place diagnostic results on a shared scale so that laboratories can produce more reliable and interoperable evidence during emerging-virus outbreaks.
Key findings
- Harmonised calibration is essential for comparable diagnostic results. • Scarce authority-issued material can anchor more widely available standards through inter-laboratory studies. • Preparedness should establish shared scales before diagnostic capacity expands during an emergency.
Why this matters globally
The approach could reduce cross-laboratory variation and strengthen international surveillance when multiple testing platforms emerge but reference materials remain scarce.
Thai researcher contribution
OpenAlex links Jeffrey J. Germer, Joseph D. Yao, and Bobbi S. Pritt to a Thai institution in this record. Formal affiliation claims should still be checked against the publisher’s article page.
Limitations to consider
This is a methodological playbook rather than a report of deployment for a specific pathogen or laboratory network. Its effectiveness depends on reference-material access, study design, and data governance.