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Global potential

Clinical and Laboratory Features of Scrub Typhus among Adult Patients with Acute Febrile Illness in Tak and Nakhon Phanom Provinces, Thailand, 2017–2020

Acute-febrile-illness surveillance from 2017-2020 identified 75 scrub-typhus cases: 39 confirmed and 36 probable. Prevalence was 6.9% in Tak versus 1.3% in Nakhon Phanom, while discharge diagnoses matched the study classification only 15% of the time. About one-quarter had coinfections. In Tak, recent forest visits and farm-animal contact were associated with 4.2- and 4.5-fold higher positivity.

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Key findings

  • Prevalence was 6.9% in Tak and 1.3% in Nakhon Phanom. • Only 15% of discharge diagnoses matched the study case designation. • Forest visits and farm-animal contact were important risk signals in Tak.
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Why this matters globally

The findings highlight likely underdiagnosis in border settings and support improved diagnostics, antibiotic management and locally targeted prevention.

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Thai researcher contribution

Thailand’s Ministry of Public Health, Mae Sot Hospital, Nakhon Phanom University and Bamrasnaradura Institute enabled surveillance across two border regions.

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Limitations to consider

The data cover two provinces in 2017-2020; some classifications relied on serology and symptoms, and results may not represent current nationwide burden.

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Verify the original sources

American Journal of Tropical Medicine and HygieneAmerican Journal of Tropical Medicine and Hygiene

DOI: 10.4269/ajtmh.25-0551

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