Information from the abstract
ABSTRACT Fungal peritonitis is a severe complication of peritoneal dialysis (PD), increasingly involving rare yeasts that challenge routine diagnostics. We report PD-associated peritonitis caused by Blastobotrys adeninivorans , initially misidentified as Candida ciferrii by automated platforms (VITEK-2 and MALDI-TOF). Persistent neutrophilic inflammation and elevated effluent β-D-glucan prompted multilocus sequencing, which confirmed B. adeninivorans . Susceptibility testing showed markedly elevated MICs to amphotericin B, azoles, and echinocandins, interpreted cautiously because validated breakpoints are unavailable. This case illustrates how persistent culture-positive PD peritonitis with discordant or unusual yeast identification should prompt molecular confirmation. Clinical resolution followed PD catheter removal and transition to haemodialysis, underscoring the importance of early source control in refractory PD-associated fungal peritonitis.
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Related topics: Antifungal resistance and susceptibility · Fungal Infections and Studies · Parasitic Diseases Research and Treatment
Thai researcher and institutional participation
Uraiwan Parinyasiri · Korawee sukmee · Banpot Suwatronnakorn · Tanittha Chatsuwan · Talerngsak Kanjanabuch · Songkhla Rajabhat University · Chulalongkorn University · Thai Red Cross Society · King Chulalongkorn Memorial Hospital
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