Information from the abstract
STUDY DESIGN: Multicenter Secondary Analysis. PURPOSE: To assess psychometric properties of a short-form Thai Version of the Spine Oncology Study Group Outcomes Questionnaire (TH-SOSGOQ-8D) among Thai patients. OVERVIEW OF LITERATURE: Although an 8-item short-form instrument was previously developed to calculate health utilities from the SOSGOQ-8D and to reduce patient burden, a gap remains regarding its local validation, serving as a critical preliminary step before calculating local-specific health utilities and QALYs. METHODS: Data for this secondary analysis were extracted from the existing validated prospective multicenter TH-SOSGOQ 2.0 database between 2018 and 2020, comprising the full analytic cohort of 68 patients and the reliability and construct validity cohort of 64 patients. The internal consistency of the instrument was evaluated through Cronbach's alpha. Test-retest reliability was reported by Intraclass Correlation Coefficients (ICC) over a one-week apart, beginning at 12 weeks post-treatment. Concurrent validity was established by correlating the short form against the original version via Pearson's correlation, whereas construct validity was examined against the EQ-5D-5 L using Spearman's rho. RESULTS: Sixty-eight participants were analyzed, reporting an average age of 57 years; 55.9% were female. Overall internal consistency was 0.832. The ICCs varied from 0.52 to 0.85, indicating moderate to excellent reliability. The TH-SOSGOQ8D showed good concurrent validity with the 27-item version, with Pearson's correlation coefficients between 0.757 and 1.000 for domains, and 0.907 for the total score. Construct validity was demonstrated by significant Spearman's rho correlations between related domains: physical function with usual activities (0.66); neurologic with mobility (0.56) and self-care (0.54); pain with pain/discomfort (0.63); mental health with anxiety/depression (0.64); social function with pain/discomfort (0.61). CONCLUSIONS: Although extracted from the existing validated Thai SOSGOQ 2.0 dataset, the TH-SOSGOQ-8D demonstrated acceptable to excellent psychometric properties. Despite being reduced to 8 items, it retained the key constructs of the original 27-item instrument. It may therefore be suitable as a disease-specific measure for health economic evaluation and clinical management of spinal tumors among the Thai population.
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Related topics: Health Systems, Economic Evaluations, Quality of Life · Economic and Financial Impacts of Cancer · Management of metastatic bone disease
Thai researcher and institutional participation
Sarunya Poolpol · Borriwat Santipas · Korawish Mekariya · Sitaporn Youngkong · Montarat Thavorncharoensap · Phantipa Sakthong · Warayos Trathitephun · Siravich Suvithayasiri · Sirichai Wilartratsami · Panya Luksanapruksa · Siriraj Hospital · Mahidol University · Chulalongkorn University · Chulabhorn Hospital
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