Information from the abstract
Bacterial cellulose (BC) is a highly pure biomaterial that can be produced from agro-industrial residues, making it a sustainable candidate for tissue engineering applications such as biocompatible hydrogel. However, pure BC is rigid and brittle, which limits its clinical handling. This study aimed to synthesise BC membranes from the non-photosynthetic bacterium Komagataeibacter nataicola (TISTR 975) using mature coconut water as the primary fermentation medium, and to improve its mechanical properties by forming an in situ composite hydrogel with polyhydroxyalkanoate (PHA). Sucrose concentration and cultivation period were systematically varied and analysed using response surface methodology (RSM), which identified the optimal condition as a 7-day cultivation at 50 g/L sucrose, yielding a highly uniform membrane with the best structural integrity. In situ fabrication of the BC/PHA composite, achieved by dispersing PHA powder in the culture medium during synthesis, markedly enhanced the material’s flexibility and water-holding capacity. The elongation at break increased from 22.9% for pure BC to 28.2% for the composite, with only a slight reduction in ultimate tensile strength. A cradle-to-gate life cycle assessment (LCA) showed that the BC/PHA membrane had a global warming potential approximately 3.2 times lower than that of bovine collagen membranes, while the incorporation of PHA introduced a negligible additional environmental burden. These findings indicate that the locally producible and biodegradable BC/PHA composite hydrogel offers a favourable balance between mechanical performance, water-holding capacity, and environmental sustainability, positioning it as a promising candidate for the future development of guided tissue regeneration (GTR) gel membranes in dentistry.
Why this record is monitored
This record has an Impact Signal of 73/100 based on recency, source, collaboration, and bibliographic signals. It prioritizes monitoring and is not a judgment of research quality.
Related topics: Advanced Cellulose Research Studies · Nanocomposite Films for Food Packaging · Membrane Separation Technologies
Thai researcher and institutional participation
Panuvit Rienpradub · Suphuttra Boonmak · Anuchan Panaksri · Sani Boonyagul · Patnarin Worajittiphon · Woradej Pichaiaukrit · Ghit Laungsopapun · Korawan Sringarm · Pornchai Rachtanapun · Kittisak Jantanasakulwong · Nuttapol Tanadchangsaeng · Rangsit University · Chiang Mai University · Thailand Institute of Scientific and Technological Research
Data limitations
This page is a bibliographic record based on abstract-level information, not a full analysis or quality assessment. Verify the DOI and original article before citation.