Information from the abstract
Abstract Introduction: Epidural steroid injections (ESIs) are commonly used for lumbosacral radicular pain, but clinical outcomes remain variable. Objective: This study aimed to identify predictive factors and determine short-term patient-reported outcomes in an understudied Southeast Asian population. Methods: A retrospective study involving 198 patients with chronic lumbosacral radicular pain undergoing lumbar ESI was conducted. Treatment success was defined as a ≥30% reduction in the Brief Pain Inventory worst pain score at 4-week follow-up. At follow-up, 167 patients had complete data and were categorized as responders (n = 83) or nonresponders (n = 84). Multivariable binary logistic regression was performed using observed complete-case data to identify factors associated with treatment success. Results: The observed 4-week response rate was 49.7%. In multivariable analysis, previous spine surgery was associated with lower odds of treatment success (adjusted odds ratio [aOR] 0.30, 95% confidence interval [CI] 0.11–0.80, P = 0.016), whereas unilateral transforaminal ESI (TFESI) was associated with higher odds of response compared with bilateral TFESI (aOR 3.16, 95% CI 1.23–8.13, P = 0.017). Baseline current pain intensity showed a negative direction of association but did not reach statistical significance (aOR 0.86, 95% CI 0.73–1.02, P = 0.086). Specific MRI findings were not significantly associated with clinical outcomes. Conclusion: Clinical history and treatment context were more informative than MRI findings for estimating short-term lumbar ESI response. Prior spine surgery was associated with poorer response, whereas unilateral TFESI was associated with higher odds of short-term treatment success.
Why this record is monitored
This record has an Impact Signal of 74/100 based on recency, source, collaboration, and bibliographic signals. It prioritizes monitoring and is not a judgment of research quality.
Related topics: Spine and Intervertebral Disc Pathology · Scoliosis diagnosis and treatment · Spondyloarthritis Studies and Treatments
Thai researcher and institutional participation
Suratsawadee Wangnamthip · Natinee Benjangkhaprasert · Nantthasorn Zinboonyahgoon · Pramote Euasobhon · Raviwon Atisook · Chanon Ngamsombat · Ruth F. Lopez · Skaorat Panchoowong · Siriraj Hospital · Mahidol University · Ramathibodi Hospital
Data limitations
This page is a bibliographic record based on abstract-level information, not a full analysis or quality assessment. Verify the DOI and original article before citation.