Information from the abstract
Overweight and obesity remain global health issues that should not be overlooked.They may impair immune health and alter the function of natural killer (NK) cells, immune effectors that may help regulate immune surveillance and associate metabolic inflammation.Therefore, the present case-control study investigated the immunological profiles of NK cells, both overall and by subpopulations [neural cell adhesion molecule 1 (NCAM1/CD56) staining: Weak (CD56 Dim ) and strong (CD56 Bright )], in 125 Thai participants stratified into five groups by lipid profiles [normal lipid (NL) and dyslipidemia (DL) and body mass index (BMI; normal weight [NW], overweight [OW] and obesity class-I (OB-I)].NK cells' immunological profiles were determined by flow cytometry.It was found that total NK cell percentages were significantly higher in the DL/OB-I group than in the NL/NW group (P
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Related topics: Immune Cell Function and Interaction · Exercise and Physiological Responses · Adipokines, Inflammation, and Metabolic Diseases
Thai researcher and institutional participation
Arpa Surapaitoon · Kiatichai Faksri · Punnapat Nawawishkarun · Supranee Phanthanawiboon · Kingkan Jaisiri · Auttawit Sirichoat · Parama Budmala · Arnone Nithichanon · Amonrat Jumnainsong · Wisitsak Phoksawat · Khon Kaen University
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