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Novel tyrosinase inhibitory peptides from Kaempferia parviflora protein hydrolysate with melanin suppression and mechanistic insights from B16F10 cells and zebrafish models

IMPACT SIGNAL70/100
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Information from the abstract

Black ginger ( Kaempferia parviflora ) is a widely used Thai medicinal rhizome, but its protein-derived fraction has not yet been widely studied for potential anti-melanogenic activity. In this work, we used bromelain to obtain the protein hydrolysate from black ginger and conducted activity-guided fractionation to obtain tyrosinase-inhibitory peptides (TIPs) with mechanistic and cellular validation. Ultrafiltration generated five molecular-weight fractions, among which the

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This record has an Impact Signal of 70/100 based on recency, source, collaboration, and bibliographic signals. It prioritizes monitoring and is not a judgment of research quality.

Related topics: melanin and skin pigmentation · Protein Hydrolysis and Bioactive Peptides · Melanoma and MAPK Pathways

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Thai researcher and institutional participation

Papassara Sangtanoo · Kittisak Kuptawach · Sajee Noitang · Tanatorn Saisavoey · Wannapawn Watsuntorn · Bodee Nutho · Onrapak Reamtong · Aphichart Karnchanatat · Simab Kanwal · Chulalongkorn University · Mahidol University · Mahidol Oxford Tropical Medicine Research Unit

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