Information from the abstract
Objective: This study aimed to develop and optimize an indomethacin (IND)-loaded nanostructured lipid carrier (NLC)-based emulgel for enhanced topical drug delivery. Material and Methods: IND-loaded NLCs were prepared at varying drug concentrations and characterized for physicochemical properties and colloidal stability. The optimized NLC formulation was incorporated into emulgels with different component ratios and evaluated for rheological properties, drug content, release kinetics, and in vitro skin permeation.Results: The NLCs containing 5.0 % w/w IND exhibited optimal physicochemical characteristics, with a particle size of 160.50±1.10 nm and a narrow size distribution (PDI
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Related topics: Advancements in Transdermal Drug Delivery · Advanced Drug Delivery Systems · Drug Solubulity and Delivery Systems
Thai researcher and institutional participation
Kanokwan Singpanna · Prasopchai Patrojanasophon · Chaiyakarn Pornpitchanarong · Nattanit Aekwattanaphol · Chanwit Changcharoensuk · Peerapat Chidchai · Siam University · Silpakorn University · Prince of Songkla University
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