Information from the abstract
Background: Sleep disturbances are highly prevalent and associated with significant health burdens, highlighting the need for safe, scalable, and non-pharmacological interventions. Functional beverages containing dietary melatonin represent a promising approach within preventive healthcare and pharmacy practice. Methods: A sequential, multi-phase, mixed-methods translational study was conducted to develop and evaluate Good Nite, an evidence-based functional sleep beverage. The study integrated (i) structured evidence synthesis and Target Product Profile development, (ii) formulation and analytical validation, (iii) market feasibility assessment using cross-sectional surveys and multivariable analysis, and (iv) economic and value evaluation using micro-costing and qualitative triangulation. Internal validity was ensured through predefined protocols, standardized instruments, and confounder adjustment Results: The final formulation demonstrated high physicochemical stability and acceptability. Market analysis showed >85% positive perception and 70–80% adoption intention, with willingness-to-pay aligned with a feasible pricing range (35–55 THB). Perceived usefulness was the strongest predictor of adoption. Pharmacists showed strong recommendation readiness (≈75–80%). Economic evaluation confirmed cost feasibility and robustness under sensitivity analyses, while qualitative findings supported high stakeholder acceptance. Conclusion: Good Nite is a clinically credible, economically viable, and scalable intervention, demonstrating strong internal validity and translational potential within pharmacy-led preventive care.
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Related topics: Business Strategies and Innovation · Sleep and related disorders · Pharmaceutical industry and healthcare
Thai researcher and institutional participation
Prayuth Poowaruttanawiwit · Kanokkarn Snae Namahoot · Naresuan University
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