Information from the abstract
Postoperative cognitive dysfunction (POCD)—characterized by deficits in memory, executive function, and processing speed—is a prevalent yet frequently underrecognized complication of surgery and anesthesia. POCD is associated with protracted recovery, diminished quality of life, and adverse long-term outcomes, particularly among elderly and high-risk populations. While early detection via bedside cognitive tests is vital for optimizing postoperative care, more comprehensive gold-standard neuropsychological batteries remain largely unfeasible in routine clinical practice due to significant time, cost, and resource constraints. This narrative review evaluates the clinical utility of practical bedside cognitive assessments for identifying POCD. Commonly employed tools—including the Montreal Cognitive Assessment (MoCA), Mini-Mental State Examination (MMSE), Trail Making Test (TMT), Digit Span, Clock Drawing Test (CDT), and Abbreviated Mental Test Score (AMTS)—are critically appraised regarding their sensitivity, limitations, and suitability for the perioperative environment. The review specifically addresses feasibility in acute postoperative settings, accounting for confounding factors such as age, literacy, and sensory or motor impairments. Furthermore, the necessity of establishing baseline cognitive status and the urgent need for tool validation within surgical cohorts are highlighted. No single bedside instrument offers a sufficiently comprehensive assessment for POCD. Rather, a multimodal approach—integrating high-sensitivity tools like the MoCA or TMT with rapid screening instruments—represents a more robust and clinically viable strategy for early detection. Future research must focus on standardizing assessment protocols and validating these tools across diverse surgical populations to ultimately enhance the quality of postoperative cognitive care.
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Related topics: Intensive Care Unit Cognitive Disorders · Anesthesia and Neurotoxicity Research · Dementia and Cognitive Impairment Research
Thai researcher and institutional participation
Sirijunya Junyatham · Napichayakarn Phanthananphokhin · Phongthara Vichitvejpaisal · Siriraj Hospital · Mahidol University
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