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Evidence of global relevance

Leucaena leucocephala fermented with Lactiplantibacillus plantarum TISTR1284 as a sustainable fishmeal substitute enhances immune responses and resistance to Aeromonas hydrophila infection in giant freshwater prawns (Macrobrachium rosenbergii)

Giant freshwater prawns received control diets or 10% and 20% fishmeal replacement with L. plantarum TISTR1284-fermented Leucaena for two weeks. Fermented diets increased immune markers and reduced post-A. hydrophila mortality by 26.14%, with normal intestinal morphology.

01

Key findings

  • Fermented diets increased antioxidant compounds, haemocytes, cell proliferation, phenoloxidase and several immune transcripts, while challenge mortality fell 26.14% without reported gut damage.
02

Why this matters globally

Fishmeal cost and marine-resource pressure make fermented plant protein relevant to tropical freshwater aquaculture and circular feed systems.

03

Thai researcher contribution

University of Phayao and Mahidol researchers integrated nutrition, fermentation, immunology and pathogen-challenge expertise.

04

Limitations to consider

The two-week study omits sample size, growth, FCR, cost and long-term residual mimosine in the abstract. Laboratory challenge is not commercial-pond performance, and transcript changes are surrogate evidence.

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Verify the original sources

Veterinary WorldRead the original article

DOI: 10.14202/vetworld.2026.2876-2898

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