A retrospective cohort of 87 cats found papillary tubular and tubulopapillary carcinomas more often at earlier stage with lower proliferation markers, while no-special-type carcinomas had the poorest prognosis. Stage, grade, margins and subtype were associated with survival. The findings inform veterinary pathology but require external validation.
Key findings
- Papillary tubular/tubulopapillary groups were linked to earlier stage (p=0.03) and lower AgNOR (p=0.02). No-special-type tumours had poorer prognosis (p=0.03), incomplete margins (p=0.004) and higher stage/grade (p
Why this matters globally
Feline mammary carcinoma is globally important, and outcome-linked classification may make veterinary pathology reports more clinically actionable.
Thai researcher contribution
Mahidol and Chulalongkorn University teams linked pathology with clinical outcomes in Thai veterinary cases.
Limitations to consider
The small retrospective sample is vulnerable to treatment, surgery and follow-up confounding. A classification adapted from human pathology needs inter-rater and external validation. These are feline, not human, findings.