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Evidence of global relevance

Sit-to-stand strategies and anticipatory momentum transfer adjustments in individuals with Parkinson’s disease using markerless motion capture: a cross-sectional study

A markerless-motion study comparing 15 people with Parkinson's disease and 15 healthy controls found longer sit-to-stand time, earlier head and trunk initiation and lower peak extension velocities.

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Key findings

  • The Parkinson's group took longer, initiated head/trunk earlier and had lower head, hip and knee peak extension velocities. Stabilization sway did not differ; AMTA1/2 durations were longer (p=0.037), with clinical correlations |r|=0.365–0.635.
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Why this matters globally

Markerless capture may improve access to movement assessment but needs accuracy and clinical-utility validation against reference systems.

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Thai researcher contribution

Mahidol and Siriraj researchers generated Thai movement data and prospectively registered the study.

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Limitations to consider

Fifteen per group limits precision. Disease severity, medication and ON/OFF state may matter; cross-sectional data do not predict prognosis, and markerless error needs validation.

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Verify the original sources

Scientific ReportsRead the original article

DOI: 10.1038/s41598-026-62250-7

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