The cohort included 5,276 ESKD patients registered with the Thai Red Cross Organ Donation Centre from 2010–2020. Age, ABO, PRA and HLA were analysed with death as a competing event.
Key findings
- Age ≥60 was associated with higher incidence (SHR 5.63); intermediate and high PRA had modest positive associations. Each additional dialysis year was associated with 29% lower incidence (SHR 0.71). ABO and HLA haplotype were not significant.
Why this matters globally
Equitable organ allocation is globally important. Competing-risk analysis is appropriate, but observed associations do not determine whether rules are fair or how points should be assigned.
Thai researcher contribution
Thai teams from Mahidol University, the Thai Red Cross Society and Thammasat University analysed national waiting-list data.
Limitations to consider
Historical allocation rules and time changes may drive associations; data end in 2020. Residual confounding remains, SHR is not an individual probability, and the strong age association requires policy-context review.