Ten Asia-Pacific experts developed 11 consensus statements on mild traumatic brain injury and use of GFAP/UCH-L1 within 12 hours. Final agreement was 90-100%, emphasizing biomarkers as adjuncts while clinical assessment and locally available imaging remain central.
Key findings
- Eleven statements were retained: seven reached 100% agreement and four reached 90%. They addressed GFAP/UCH-L1 testing within 12 hours, challenging subgroups and integration with clinical and imaging pathways.
Why this matters globally
A regional framework matters because CT access, assay costs and referral systems vary widely across Asia-Pacific settings, informing technology assessment and local guidance.
Thai researcher contribution
Thai clinicians and institutions from Bangkok Hospital, the Thai Red Cross Society, Chulalongkorn University and King Chulalongkorn Memorial Hospital contributed to regionally grounded consensus.
Limitations to consider
Only ten selected experts participated. Consensus is not evidence of sensitivity, specificity, CT reduction or improved outcomes. Implementation depends on cut-offs, platforms, timing, cost, conflicts of interest and local validation.