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Evidence of global relevance

Prevalence and Factors Associated with Depression in Pediatric Epilepsy Patients at Maharat Nakhon Ratchasima Hospital

A cross-sectional study of 141 children aged 10–15 with epilepsy found positive depression screening in 19.9%, associated with age, female sex, generalized seizures and a seizure-frequency category.

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Key findings

  • Twenty-eight of 141 children (19.9%) screened positive. Adjusted odds were higher with each year of age (OR 1.60, 95% CI 1.13–2.26), female sex (3.29, 1.11–9.81), generalized seizures (4.04, 1.32–12.35) and a less-than-monthly to every-three-months seizure category versus daily seizures (5.70, 1.55–20.99).
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Why this matters globally

The findings support integrating mental-health screening into paediatric epilepsy care, where emotional symptoms can be overshadowed by neurological concerns.

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Thai researcher contribution

The Maharat Nakhon Ratchasima team generated practice-based Thai evidence using a Thai-language screening instrument.

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Limitations to consider

This single-hospital cross-sectional study has wide confidence intervals for some estimates. Screening can yield false positives, and the counterintuitive seizure-frequency association may reflect a small reference group or residual confounding.

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Verify the original sources

Journal of Child ScienceRead the original article

DOI: 10.53391/2474-5871.1014

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