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Evidence of global relevance

Effects of nitrogen deficiency on grain quality and functional properties of protein hydrolysates in a low-nitrogen-tolerant rice mutant (MT2)

The KDML105-derived MT2 rice mutant showed genotype-specific grain and proteomic responses to low nitrogen. Nitrogen deficiency reduced some glutelin and allergenic proteins and yielded hydrolysates with stronger in-vitro antibacterial activity, but this is not clinical nutrition evidence.

01

Key findings

  • MT2 had higher carbohydrate and amylose. Under sufficient nitrogen it accumulated functional proteins and produced highly antioxidant hydrolysates; low nitrogen reduced selected glutelin/allergenic proteins and induced MT2-specific proteins correlated with antioxidant and antibacterial assays.
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Why this matters globally

If confirmed in fields and foods, low-nitrogen-tolerant varieties and fertilizer management could reduce inputs while creating higher-value ingredients. Yield, seasonal stability and whole-system environmental effects remain essential.

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Thai researcher contribution

Mahidol University researchers collaborated with NSTDA and BIOTEC proteomics scientists, combining a Thai rice background with national molecular-biology infrastructure.

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Limitations to consider

Controlled nutrient solution is not multi-location farming; protein correlations do not prove mechanism. Hydrolysate assays do not establish digestion, bioavailability, safety or human effects, and proposed low-glutelin or glycemic benefits require testing in cooked food and people.

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Verify the original sources

Scientific ReportsRead the original article

DOI: 10.1038/s41598-026-61377-x

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