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Evidence of global relevance

Tapping-Induced Oxidative Stress Is Associated with Hev b6 Allergen Regulation in Hevea brasiliensis

In RRIT251 rubber trees, tapping versus no tapping was associated with about 2.17-fold higher ROS, 2.3-fold Hev b6 gene upregulation and roughly 220 µg/mL Hev b6 in latex. The study links mechanical wounding to plant-defense and allergen regulation but did not measure human allergy.

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Key findings

  • Most allergen genes decreased, while Hev b6 and Hev b11 rose, particularly Hev b6. Plant-pathogen, MAPK and WRKY pathways aligned with ROS; catalase increased whereas total SOD did not, indicating a selective defense response.
02

Why this matters globally

Global latex-product industries need upstream allergen management. Understanding tapping-related regulation could eventually guide clone selection and harvesting practice.

03

Thai researcher contribution

Five Prince of Songkla University researchers across science, pharmacy, medical technology and biochemistry studied the Thailand-relevant RRIT251 clone.

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Limitations to consider

Tapped versus untapped comparisons may be affected by age, season, sampling time or yield; sample and replication detail are absent from the abstract. Latex protein concentration is not finished-product exposure or human IgE response, and only one clone was studied.

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Verify the original sources

International Journal of Molecular SciencesRead the original article

DOI: 10.3390/ijms27146110

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