The Remission Therapy Inquiry-Based Research Model uses True Remission as a conceptual lens, not a validated biological endpoint. Twelve self-inquiry questions and a route-based roadmap aim to make pre-experimental mechanistic reasoning transparent and traceable.
Key findings
- The paper argues that reproducible reasoning should complement reproducible outcomes: researchers should expose how mechanisms were selected, alternatives excluded and clinical phenomena linked to restoration before empirical testing.
Why this matters globally
If operationalized, the framework could support teaching, protocol review and multiscale study design where data are abundant but mechanistic explanations remain fragmented.
Thai researcher contribution
Authors from the Thai Red Cross Society and Chulalongkorn University's preventive and integrative medicine center developed the framework with a Liverpool affiliation.
Limitations to consider
True Remission may invite therapeutic overinterpretation. There is no scoring validity, inter-user reliability or evidence that generated hypotheses are more novel, testable or successful; an algorithmic roadmap does not eliminate subjective judgment.