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Evidence of global relevance

Effectiveness and Implementation of the SHIELD Integrated Multi-level Model to Reduce Adolescent Depression and Internet Addiction: A Cluster Randomized Waitlist-Controlled Trial in Wangchin District, Phrae Province

A cluster-randomised waitlist-controlled trial in eight schools in Wang Chin, Phrae, enrolled 240 at-risk students aged 12–18. The 12-week SHIELD programme reduced depression and internet-addiction scores, improved response and remission, and was cost-effective under the study threshold. The evidence is stronger than an observational study but needs replication across provinces and longer follow-up.

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Key findings

  • At six months, adjusted mean differences were −3.1 PHQ-9 points (95% CI −4.0 to −2.2; d=0.68) and −11.2 IAT points (95% CI −14.8 to −7.6; d=0.67). A ≥50% PHQ-9 response occurred in 64.8% versus 25.5% (OR 5.4; NNT 3), and remission in 35.2% versus 11.8% (OR 4.1; NNT 5). Fidelity was 88.4%, school adoption 100%, and ICER 12,830 THB per depression-free year versus the study threshold of 34,400 THB.
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Why this matters globally

SHIELD demonstrates how mental health and digital well-being can be integrated in resource-constrained schools while measuring outcomes, implementation and economics. Scaling requires referral capacity and should not replace individual clinical care.

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Thai researcher contribution

Seubtrakul Tantalanukul of Boromarajonani College of Nursing Uttaradit, Praboromarajchanok Institute, and Amornpan Samorn of Wang Chin Hospital developed and tested the programme directly in rural Thailand.

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Limitations to consider

Only eight schools in one district were included, with few clusters and a waitlist rather than active control. Six-month follow-up does not establish long-term durability, and economic results depend on costing assumptions and the selected threshold.

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Verify the original sources

Chulalongkorn Medical JournalRead the original article

DOI: 10.56808/2673-060x.5733

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