Baseline ENRICh-II data covered 519 adults diagnosed within the prior year across six ambulatory oncology clinics. Mean age was 52 and 67.2% were women. Financial toxicity, life satisfaction, state hope and social support were measured. Greater toxicity correlated with lower satisfaction (r=-0.34). Hope and support statistically partially mediated the association, with indirect effects of -0.08 and -0.03, also across material, coping and distress domains. The authors propose psychosocial resilience alongside financial assistance.
Key findings
- N=519; financial toxicity-SWL r=-0.34; support indirect effect -0.03 (95% CI -0.06,-0.01); hope -0.08 (-0.12,-0.03); combined path significant; patterns spanned subdomains.
Why this matters globally
The study frames financial toxicity as both material and psychosocial, supporting oncology navigation that combines benefits, travel, employment, debt, counseling and support networks.
Thai researcher contribution
David B. Feldman is affiliated with Chulalongkorn University in an international psycho-oncology network contributing resilience and quality-of-life perspectives.
Limitations to consider
Cross-sectional mediation cannot establish sequence; low satisfaction may alter hope or perceived support. Six clinics and recently diagnosed patients may not generalize, socioeconomic confounding remains possible, and psychosocial support cannot replace material relief.