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Updated safety and efficacy of puxitatug samrotecan (Puxi-Sam, AZD8205) in patients (pts) with endometrial cancer (EC) or ovarian cancer (OC): Phase 1/2a BLUESTAR study.

This BLUESTAR conference update reports early safety and response signals for a B7-H4-directed antibody-drug conjugate in relapsed or metastatic endometrial and ovarian cancer. It is dose-development evidence, not comparative or survival proof.

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Key findings

  • This BLUESTAR conference update reports early safety and response signals for a B7-H4-directed antibody-drug conjugate in relapsed or metastatic endometrial and ovarian cancer. It is dose-development evidence, not comparative or survival proof.
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Why this matters globally

This work adds internationally comparable evidence in Health sciences and defines questions for replication in other populations or systems. Its global value lies in the evidence and transferable reasoning, not in a single impact score.

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Thai researcher contribution

Thailand-linked authors and Chiang Mai University contribute to the research network behind this work. Thai participation is identified from bibliographic affiliations and should be checked against the author list and source article.

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Limitations to consider

These are preliminary, detail-limited results that may change with longer follow-up, complete analysis and full publication.

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Verify the original sources

Journal of Clinical OncologyRead the original article

DOI: 10.1200/jco.2026.44.16_suppl.5515

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