Twenty patients received traditional Thai oral formulations plus herbal cream for 12 weeks. PASI and DLQI improved, while molecular docking suggested interactions with COX-2 and IL-6.
Key findings
- PASI and DLQI improved
- No serious adverse effects were reported
- Docking implicated COX-2 and IL-6
Why this matters globally
The study adds preliminary evidence linking traditional Thai psoriasis treatment with clinical outcomes and molecular-docking hypotheses. If confirmed in larger controlled trials, it could contribute to evidence-based evaluation of herbal formulations and integrative care. At present, however, the findings should not be treated as definitive proof of efficacy or as a replacement for established psoriasis treatment.
Thai researcher contribution
Researchers from Thaksin University, Prince of Songkla University and a Traditional Thai Medicine Hospital contributed.
Limitations to consider
The study lacked a control group, had a small sample and docking results do not confirm mechanism in humans.