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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
HIV, Ageing and Metabolic Health89IMPACT SIGNAL
Longitudinal observational cohort evidence

Metabolic Dysfunction‐Associated Steatohepatitis and the Progression of Cognitive Decline in Older Thai People With HIV

This prospective HIV-NAT cohort in Bangkok followed 291 people with HIV aged at least 50 years from 2015–2024; 60 participants, or 20.6%, met non-invasive criteria for MASH at baseline. Over a median 5.9 years, baseline MASH was associated with steeper decline in Thai-validated MoCA scores after adjustment for multiple metabolic, social, and HIV-related factors, whereas MASLD without the MASH signal was not associated with decline. The findings support integrated liver and cognitive surveillance but do not show that treating MASH prevents cognitive deterioration.

Thai researchersKatekarn Porkaew · Akarin Hiransuthikul · Win Min Han · Tanakorn Apornpong · Sasiwimol Ubolyam · Stephen John Kerr · Anchalee Avihingsanon
Sports Science and Youth Development88IMPACT SIGNAL
Exploratory cross-sectional evidence

Early neuromuscular and cognitive signatures in high-performance young male Muay Thai athletes

Researchers assessed 215 high-performance male Muay Thai athletes aged 8–18 over five days and compared four age groups. Anthropometry, biological maturation, maximal strength, and several cognitive measures improved with age, while limb asymmetry, fatigue indices, Nordic hamstring performance, lower-limb dynamic strength index, and upper-limb push-up force did not differ by age. PCA suggested age-specific multidimensional profiles, but cross-sectional data do not prove an effect of age or training and do not constitute a validated talent-selection model.

Thai researchersPhornpot Chainok · Naruepon Vongjaturapat · Nattasit Suwannawat · Atcharat Yongtawee
Patient-Reported Outcome Measurement86IMPACT SIGNAL
Qualitative evidence from patient experience

Measuring what matters: Evaluating quality of life instruments through the eyes of people with Parkinson's disease

Researchers asked 31 people living with Parkinson's disease to complete eight quality-of-life instruments and then used semi-structured interviews to explore what helped or hindered meaningful reporting. Participants favored broad response options, attention to personal, emotional, and practical effects, clear and specific language, and a balance of positive and negative questions. The study centers lived experience in instrument refinement but does not establish which questionnaire has the best validity, reliability, or responsiveness.

Thai researchersOnanong Phokaewvarangkul
Business, Marketing and Consumer Behaviour86IMPACT SIGNAL
Survey and configurational-model evidence

Balancing continuity and relevance: Innovation-nostalgia configurations in time-honored brand revitalization

Revitalizing a time-honored brand requires continuity of identity alongside present-day relevance. The study analyzed 404 firm-side respondents from 76 enterprises and 536 consumers in Southwestern China using PLS-SEM and fsQCA. Innovation and nostalgia interacted positively only in the firm model; both were positively associated on the consumer side, where nostalgia was stronger. Set-theoretic analysis identified overlapping configurations and three balancing logics, framing revitalization as a multi-actor process rather than a universal formula.

Thai researchersXiangyu Li · Danaikrit Inthurit · Surachai Kungwon · Nirote Sinnarong
Sustainable Tourism and Climate Risk85IMPACT SIGNAL
Cross-sectional structural and configurational evidence

Revisit Intention Under Climate Risk in Island Tourism: Structural and Configurational Evidence from PLS-SEM and fsQCA

The study examines how perceived island-climate risk, destination climate resilience, tourism climate-service usefulness, and destination trust combine in relation to intention to revisit Phuket. An on-site survey of 480 Chinese tourists was analyzed using both PLS-SEM and fsQCA. The structural model explained 74.6% of variance in revisit intention: perceived climate risk was negatively associated, the other three constructs were positively associated, and trust had the strongest direct association. The configurational analysis identified multiple routes to high and low intention. All results concern cross-sectional self-reported intention, not proof that an intervention causes actual return travel.

Thai researchersXinda Yang · Sirichai Preudhikulpradab · Lalida Arphawatthanasakul
Health Professions Education and Research Equity85IMPACT SIGNAL
Global bibliometric and network analysis

Moving towards decolonizing health professions education research: an analysis of global network patterns and equity implications

An all-Thai team analyzed co-authorship structures in five leading Q1 health-professions-education journals from 2015 through 2024, covering 13,187 publications, 45,366 authors, and affiliations in 162 countries. Annual output grew 2.7-fold and distinct authors 3.7-fold. High-income-country-only publications fell from 86% to 63%, while non-high-income-only publications rose from 6% to 26%. The network became broader and more connected, yet the United States, United Kingdom, and Canada remained central, and low-income-country collaboration was more often routed through high-income partners than through regionally led networks.

Thai researchersPeerasit Sitthirat · Seksan Yoadsanit · Phuphinyo Limchantra · Kanjaree Suppawittaya · Suttithan Suwannoppakun · Piwat Suppawittaya · Phanuwich Kaewkamjornchai · Somsak Chunharas
Healthcare Operations and Decision Support85IMPACT SIGNAL
Computational simulation evidence

An Integrated Intelligent Decision Support System Combining Stochastic Programming and Queuing Theory for Dynamic Triage of Surgical Critical Care Patients to Prevent Postoperative Complications in Healthcare Business Operation

The authors developed SQDSS, combining two-stage stochastic programming with multi-class priority queueing to triage surgical critical-care patients under uncertain arrivals, changing acuity, and deterioration while waiting. Across 48 synthetic datasets, comparisons with first-come-first-served and a fixed-severity rule showed about 22.8% shorter high-acuity waits, 16% greater bed utilization, roughly 28% less queue overflow, and roughly 18% fewer simulated complications. Benefits were greatest under surge and trauma-dominant conditions. No real-patient data or implementation trial were used, so these results demonstrate modeled feasibility rather than clinical effectiveness.

Thai researchersJarun Bootdachi · Parichat Wonggom · Wiphawadee Potisopha
Adolescent Mental Health and Measurement85IMPACT SIGNAL
Psychometric validation

Psychometric Properties of the Revised Thai Rosenberg Self-Esteem Scale (r-TRSES) in Adolescents: Confirmatory Factor Analysis and Rasch Modeling

The study evaluates a culturally reworded Thai Rosenberg Self-Esteem Scale in 443 boarding-school students. Confirmatory factor analysis supported a bifactor structure with a dominant general self-esteem factor and residual wording-related variance. Rasch analysis supported essential unidimensionality, acceptable item fit, strong reliability, and ordered response thresholds. No item exceeded the prespecified threshold for sex differential item functioning. Scores correlated positively with resilience (r=0.589) and negatively with depressive symptoms (r=-0.601), but precision declined among adolescents with higher self-esteem and broader replication remains necessary.

Thai researchersJustin DeMaranville · Peerapat Naprung · Supisara Prompila · Nahathai Wongpakaran · Tinakon Wongpakaran
Clinical-Trial Systems and Research Capacity88IMPACT SIGNAL
Expert-workshop open letter; version 1 awaiting peer review

Strengthening Sustainable Clinical Trial Models for Greater Health Impact: Expert Discussion from the Annual Wellcome Major International Programme Regional Meeting 2024

This open letter synthesizes the 2024 Wellcome Major International Programmes meeting, which brought together research-institution representatives from Africa, Asia, and the United Kingdom. Participants identified limited clinical-trial literacy, unstable funding, workforce recruitment and retention, inequitable partnerships, ethics and regulatory bottlenecks, operational inefficiencies, and barriers in remote settings. Proposed responses included locally led agendas, diversified funding, workforce development, stronger community and regulator engagement, platform, adaptive and decentralized trials, shared monitoring, and interoperable data systems. The meeting agreed to explore a formal MIPs alliance, but the paper does not show that the alliance has yet delivered operational or health outcomes.

Thai researchersNicholas P J Day · Nicholas J White
Generative AI and Higher Education85IMPACT SIGNAL
Cross-sectional PLS-SEM evidence

Extending UTAUT with Metacognition and Self-Regulation: Evidence on Generative AI Use among University Students

A survey of 451 students at seven Thai Rajabhat universities extended UTAUT by positioning metacognitive awareness and self-regulated learning between technology-acceptance determinants and GenAI-use intention, with intention predicting self-reported use of GenAI as a cognitive partner. Facilitating conditions had the strongest associations with metacognition and self-regulation but no significant direct association with intention; the significant indirect path ran through metacognition. Social influence was the strongest direct predictor of intention, followed by metacognition, while effort expectancy and self-regulated learning did not predict intention in this model.

Thai researchersNatthawan Phoonson · Thada Jantakoon · Rukthin Laoha
Geriatric and Transitional Care85IMPACT SIGNAL
Prospective observational evidence

Nearly Two-Thirds of Frail Older Adults Had an Unplanned Hospital Return Within Six Months

An interim prospective secondary analysis from a parent trial at one university hospital followed 170 frail older adults after medical-ward discharge. A broad composite of emergency visits, unplanned outpatient visits, and readmissions rose from 34.7% at one month to 64.7% at six months. Better nutritional status was associated with lower return odds, and returners had higher direct medical costs. The observational analysis does not show that nutritional intervention prevents return.

Thai researchersPatumporn Suraarunsumrit · Maytinee Srisubin · Sutisa Pitiyarn · Ponnapa Petchthai · Dariya Tantiameorn · Chaloemphon Thedpun · Sunit Jarungjitaree · Kotchamon Sukyoyot · Unchana Sura-amonrattana · Varalak Srinonprasert · Titima Wongviriyawong
HIV Prevention and Health Equity92IMPACT SIGNAL
Cross-national cross-sectional evidence

PrEP Use and Willingness Cascades Among Transgender Women in 11 Asian Countries: Findings From the PrEP APPEAL Cross-Sectional Online Survey

The 2022 PrEP APPEAL online survey included 1,178 transgender women in 11 Asian countries. Awareness was 80.0%; among those aware, 62.6% had ever used PrEP, and 78.1% of ever-users were current users. Among higher-risk PrEP-naïve respondents, 60.0% were willing to use it, but only 34.0% of those willing would pay. Healthcare discrimination was associated with lower lifetime use; causality cannot be inferred.

Thai researchersRena Janamnuaysook · Hua Boonyapisomparn · Nittaya Phanuphak
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
74IMPACT SIGNAL
Clinical Medicine

Tooth surface loss associated with unshelled sunflower seed consumption: a scoping review

Frontiers in Oral Health

Thailand-affiliated authors
Thantrira Porntaveetus
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

An Optimized Protocol for the Differentiation and Fibrosis-Associated Transcriptional Priming of THP-1 Macrophages

Methods and Protocols

Thailand-affiliated authors
Janya Khattiya · Chareeporn Akekawatchai
Institutions
Thammasat University
74IMPACT SIGNAL
Global Public Health

Unraveling Hepatic Osmoregulation in Teleost: Metabolic Reprogramming and Signal Transduction in Salinity Adaptation

Reviews in Aquaculture

Thailand-affiliated authors
Sukree Hajısamae · Ilham Zulfahmi
Institutions
Prince of Songkla University
74IMPACT SIGNAL
Clinical Medicine

Etiology and clinical severity of community-acquired acute gastroenteritis in adults at a coastal provincial hospital in Thailand

Scientific Reports

Thailand-affiliated authors
Nant The Su Mon · Sirirat Phuttasiriwat · Saranath Lawpoolsri · Kittiyod Poovorawan · Sant Muangnoicharoen · Hisham A. Imad · Prakaykaew Charunwatthana · Chatporn Kittitrakul
Institutions
Mahidol University · Samut Sakhon Hospital · Mahidol Oxford Tropical Medicine Research Unit
74IMPACT SIGNAL
Clinical Medicine

In vitro and in silico antiviral activity of Polyscias scutellaria leaf extract against drug-susceptible and drug-resistant herpes simplex virus and human papillomavirus-positive cervical cancer: implications for topical formulation development

Virus Research

Thailand-affiliated authors
Rapeepat Tipayawong · Wiratchanee Kansandee · Chaleampol Loymunkong · Padtaya Sirinantananon · Sirirat Mahawan · Kans Suwanmali · Nattarpart Lookluck · Chamsai Pientong · Tipaya Ekalaksananan · Jureeporn Chuerduangphui
Institutions
Kasetsart University · Khon Kaen University
74IMPACT SIGNAL
Clinical Medicine

Repurposing Thiazole/Benzothiazole-Based Thiazolidinone Derivatives as SARS-CoV-2 Main Protease (Mpro) Inhibitors: An Integrated Computational and Experimental Study

BioChem

Thailand-affiliated authors
Hathaichanok Chuntakaruk · Thanyada Rungrotmongkol
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine

Proteomics-guided characterization of Hericium erinaceus protein-capped silver nanoparticles for cytotoxicity against cancer cells and improved hemocompatibility

OpenNano

Thailand-affiliated authors
Siripong Sukdee · Onmanee Prajuabjinda · Panita Chutimanukul · Preuk Chutimanukul
Institutions
Thammasat University
74IMPACT SIGNAL
Clinical Medicine

Development and evaluation of a multiplex PCR for simultaneous detection of Mycobacterium tuberculosis complex, Mycobacterium avium complex, and Burkholderia pseudomallei in clinical specimens

PLoS neglected tropical diseases

Thailand-affiliated authors
Hasyanee Binmaeil · Thanakon Bunsong · Janjira Thaipadungpanit · Soawarat Deekae · Sunee Chayangsu · Wang Nguitragool · Narisara Chantratita
Institutions
Mahidol University · Surin Hospital
74IMPACT SIGNAL
Clinical Medicine

Risk Factors and Outcomes of Postoperative Pulmonary Embolism in Southeast-Asian Patients Undergoing Major Surgery: A Nested Case-Control Study

Journal of Surgical Research

Thailand-affiliated authors
Nittaya Boonsri · Patteera Apiwatanakul · Sirawit Sayananon · Nichawan Koompong · Thanyawit Ninlaphut
Institutions
Mahidol University · Ramathibodi Hospital
74IMPACT SIGNAL
Clinical Medicine

Acute pharmacologic treatment versus observation for severe asymptomatic hypertension in emergency and acute care settings: a systematic review of short-term outcomes

BMC Emergency Medicine

Thailand-affiliated authors
Thanat Tangpaisarn · Wachira Wongtanasarasin · Kasidit Na Thalang · Praew Kotruchin
Institutions
Khon Kaen University · Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Discriminative ability and exploratory cutoff of six-minute walk distance for recent self-reported fall history in community-dwelling older adults with type 2 diabetes

BMC Geriatrics

Thailand-affiliated authors
Chiraphat Kloypan · Boonsita Suwannakul · Chakkraphan Hongluek · Tichanon Promsrisuk · Arunrat Srithawong
Institutions
University of Phayao
74IMPACT SIGNAL
Environmental Engineering

Factors affecting the release of microfibers and microplastics from laundry activities: type, quantity, and properties

Journal of Hazardous Materials Advances

Thailand-affiliated authors
Kanitchanok Muangkaew · Tunlawit Satapanajaru · Kanthika Nonthamit · Adisorn Songkun · Phonchai Noomvong · Supawit Rungmueanfa · Maneekarn Yoo-iam · Piyarat Vijuksungsith
Institutions
Kasetsart University
74IMPACT SIGNAL
Clinical Medicine

Ogataea Yeast Platform for Recombinant Porcine Interferon-Alpha 1 Production: Toward Alternative Biotherapeutics for Swine Health Management

Microorganisms

Thailand-affiliated authors
Benjamas Liwnaree · Thorntun Deangphare · Chinnawat Assana · Kitisak Sansatchanon · Jedsadakorn Ninrat · Jaraspim Narkpuk · Nanchaya Wanasen · Aekkachai Puseenam · Niran Roongsawang · Kanokarn Kocharin · Peera Jaru-Ampornpan
Institutions
National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
74IMPACT SIGNAL
Clinical Medicine

BIA-estimated visceral fat level and selected regional body composition measures are associated with high-sensitivity C-reactive protein in Thai adults

Scientific Reports

Thailand-affiliated authors
Surachat Buddhisa · Surada Satthakarn · Nattaphol Prakobkaew · Tadsawiya Padkao · Orachorn Boonla · Piyapong Prasertsri
Institutions
Burapha University
74IMPACT SIGNAL
Clinical Medicine

Virtual Phase-Contrast Microscopy for Urinary Sediment Analysis: Deep-Learning-Based Image Translation from Brightfield Microscopy

Applied Sciences

Thailand-affiliated authors
Ruchirat Rotbun · Tipparat Penglong · Atthaphong Phongphithakchai · Chonikarn Nuhom · Peempol Chokchaipermpoonphol
Institutions
Prince of Songkla University
74IMPACT SIGNAL
Clinical Medicine

Association between early systolic blood pressure and clinical outcomes in non-critically ill patients with sepsis-associated acute kidney injury: a retrospective cohort study

Annals of Medicine

Thailand-affiliated authors
Teerawat Sriwalosakul · Surachet Vongsanim · Karn Pongsuwan · Prit Kusirisin · Surapon Nochaiwong · Chidchanok Ruengorn · Kajohnsak Noppakun
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Parkinson’s disease assessment with selfie video via feature engineering and explainable AI

PLoS ONE

Thailand-affiliated authors
Sitthatka Jaratsaeng · Anchalee Techasen · Narongrit Kasemsap · Thanapong Intharah
Institutions
Khon Kaen University
74IMPACT SIGNAL
Clinical Medicine

The Effect of Fine (PM2.5) and Coarse (PM10-2.5) Particulate Matter on Survival Outcomes in Nasopharyngeal Carcinoma Patients: A Retrospective Cohort Study in a Northern Thailand Tertiary Care Center

Journal of Clinical Medicine

Thailand-affiliated authors
Weerachai Watcharatsiriyuth · Phakhinee Leesirisopha · Pichit Sittitrai · Hanpon Klibngern · Tapanut Ariyanon · Orapan Sangiamporn · Donyarat Ruenmarkkaew
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

[2026-09-22] Efficacy and Safety of PCSK9 Inhibitors in Patients With Atherosclerotic Cardiovascular Disease at a Tertiary Hospital in the Northeast of Thailand

Research Medical Journal

Thailand-affiliated authors
Pattaraphon Tangsucharit · Chaiyasith Wongvipaporn · Naowakun Ariyapim · Chitsanupong Sumlee
Institutions
Khon Kaen University
74IMPACT SIGNAL
Clinical Medicine

Preliminary Clinical Evaluation of Inhalation Aromatherapy with Blended Essential Oils on Sleep Quality in Adults with Sleep Disturbance

Journal of Health Research

Thailand-affiliated authors
Punyanut Amorndoljai · Laddawan Choothong · Surachai Techaoei · Em–on Chaiprateep
Institutions
Rajamangala University of Technology
74IMPACT SIGNAL
Clinical Medicine

A Registry-Informed Framework for Earlier Detection of Esophageal Adenocarcinoma in Thailand: Evidence from a 16-Year Cohort Study

Methods and Protocols

Thailand-affiliated authors
Thanawat Suwatthanarak · Kullanist Thanormjit · Onchira Acharayothin · Patcharipa Chanaturakarnnon · Sripatch Sri-arporn · Tippawan Gerdsuriwong · Kanokporn Thamapala · Thapanee Saejeng · Arthit Chauykrajang · Wipanee Meesil · Tharathorn Suwatthanarak · Somsri Laiteerapong · Thammawat Parakonthun · Jirawat Swangsri · Asada Methasate · Vitoon Chinswangwatanakul · Pariyada Tanjak
Institutions
Siriraj Hospital · Mahidol University
74IMPACT SIGNAL
Multidisciplinary

Intercellular space limitation and ripening-associated sugar changes are associated with watercore susceptibility in durian fruit

Postharvest Biology and Technology

Thailand-affiliated authors
Naphassorn Sungtin · Kamonwan Sangsoy · Jingtair Siriphanich · Tee Havananda · Kietsuda Luengwilai
Institutions
Kasetsart University · Ministry of Higher Education, Science, Research and Innovation
74IMPACT SIGNAL
Clinical Medicine

Novel endoscopic treatment to prevent refractory caustic esophageal strictures: a propensity score-matched analysis

Surgical Endoscopy

Thailand-affiliated authors
Thitiporn Chobarporn · Dudsadee Mesiri · Papawee Chennavasin · Chadin Tharavej
Institutions
Chulalongkorn University · King Chulalongkorn Memorial Hospital
74IMPACT SIGNAL
Multidisciplinary

Preparation and Production of Bio‐Epoxy Composites From Sisal Fibers as a Sustainable Material for Lightweight Applications

Macromolecular Symposia

Thailand-affiliated authors
Timothy K. Mulenga · Resego Phiri · Sanjay Mavinkere Rangappa · Suchart Siengchin
Institutions
King Mongkut's University of Technology North Bangkok
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link