The multicountry EFFORT trial compares shorter radical-cure strategies under unsupervised, real-world use in people meeting a G6PD activity threshold. Its practical value lies in balancing recurrence prevention and adherence against haemoly…
Journal
The Lancet Infectious Diseases
Thai researchers
Rupam Tripura · Bipin Adhikari · Mom Ean · Meas Sokha · Tom Peto
Thai institutions
Mahidol Oxford Tropical Medicine Research Unit · Mahidol University
Analysis of three Indian national family-health surveys estimates stillbirth at 20-, 24- and 28-week thresholds and maps state and district variation. Earlier gestational thresholds expose losses that routine 28-week reporting can systemati…
Proteomic and phosphoproteomic profiling identifies plasma small-vesicle pFLNA-Ser1459 as a candidate marker across healthy controls, high-risk adenoma and colorectal cancer. Independent blinded validation and an analytically standardised a…
In an international placebo-controlled phase 3 trial of 589 hospitalised adults, adding ensitrelvir to standard care did not significantly improve the day-60 recovery outcome. The result argues against broad inpatient benefit while leaving …
Journal
Clinical Infectious Diseases
Thai researchers
Methee Chayakulkeeree · Piroon Mootsikapun · Napon Hiranburana
Thai institutions
Siriraj Hospital · Mahidol University · Khon Kaen University · Chulalongkorn University
Random Forest models compare environmental and spatial predictors of Thai Paphiopedilum distributions to prioritise surveys and conservation. Sampling bias, imperfect detection and changing habitat can make static suitability maps appear mo…
Semi-structured interviews with 16 orthodontic professionals build a multilevel framework of motivations, barriers and enablers for lifelong learning, including AI-supported approaches. The small qualitative framework needs quantitative and…
The protocol standardises monocyte isolation, macrophage differentiation, K562 preparation and pH-sensitive flow cytometry to distinguish binding from internalisation. It improves mechanistic reproducibility but does not demonstrate patient…
A PRISMA-guided review searches four databases and groups AI for urodynamics into parameter-, raw-signal- and image-based approaches. Small datasets, bias and limited external validation prevent a conclusion that these tools are deployment-…
A February 2025 Indiana University workshop asked over twenty international experts to pressure-test propositions about dietary protein: methodological limitations, ‘optimal’ intake for muscle synthesis, accretion, growth and repair, needs …
Eighty untreated low-risk Thai adults with acute influenza provided duplicate daily oropharyngeal swabs for 14 days with qPCR viral density. Growth-and-decay fit best, while exponential decay was most parsimonious. Median half-life was 10.3…
Journal
Philosophical Transactions of the Royal Society B
Thai researchers
Phrutsamon Wongnak; Tim Seers; Podjanee Jittamala; Mallika Imwong; William Schilling; Nicholas J. White
Red-cell invasion is essential to malaria. P. falciparum uses a PCRCR complex, but Rh5 is species restricted. Orthologs of PTRAMP, CSS and Ripr from P. falciparum, P. vivax and P. knowlesi formed disulfide-linked PTRAMP-CSS heterodimers and…
Japan's national surveillance from January 2017 to October 2025 identified 288 IMD cases across pre-pandemic, pandemic and reopening phases. Cases fell from 48 in 2019 to one in 2021, then rose to 66 in 2024 and 68 by October 2025. Older ad…
Journal
Tropical Medicine and Health
Thai researchers
Y. Chen; Hirotake Mori; Rapeephan R. Maude
Thai institutions
Mahidol University; Ramathibodi Hospital; MORU; Bumrungrad International Hospital
This scoping review included 76 Southeast Asian studies published since 2000: 28 mortality, 38 morbidity and 10 effect-modification studies. Minimum-risk temperatures and thresholds varied widely by location and outcome. Reported relative r…
The study integrates CO2 emissions, ecological footprint and load-capacity factor to represent emissions, resource demand and regenerative capacity in India. Annual 1969-2023 data were analyzed with ARDL bounds testing and robustness estima…
This review traces optical point-of-care biosensors from plasmonic materials, quantum dots, MOFs and MXenes that amplify signals and lower detection limits to integration with microfluidics, AI and the Internet of Medical Things. Discussed …
Networked nanosensor data are high-dimensional, incomplete, noisy and nonlinear, challenging both first-principles and purely data-driven models. This review presents physics-informed supervised learning that embeds conservation laws, stoch…
Phosphate glasses with fixed Tb2O3 and varying Eu2O3 were produced by melt quenching. XRD confirmed amorphous structure and FTIR identified bridging and non-bridging oxygen. Green Tb3+ and red Eu3+ emissions, together with lifetime behavior…
Journal
Vacuum
Thai researchers
P. Kanjanaboos; N. Intachai; S. Kothan; N. Kiwsakunkran; N. Chanthima; J. Kaewkhao
Thai institutions
Mahidol University; Chiang Mai University; Nakhon Pathom Rajabhat University
Patients with muscle-invasive bladder cancer who cannot receive cisplatin have had limited perioperative options. This trial randomized 344 participants to enfortumab vedotin plus pembrolizumab before and after surgery or to surgery alone. …
Burkholderia pseudomallei is difficult to detect environmentally with conventional culture. CRISPR-BEEPs was benchmarked against plate inspection using double-qPCR as reference. Sensitivity was 93.5% versus 19.4%, with specificity of 100% v…
Journal
Nature Communications
Thai researchers
Sukritpong Pakdeerat, Chalita Chomkatekaew, Phumrapee Boonklang and the Thai research network
Thai institutions
Mahidol University; MORU; Burapha University; VISTEC; Kasetsart University; Sappasithiprasong Hospital; Chulalongkorn University; Chiang Mai University
BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and neuronal loss. Evidence links gut-brain axis dysfunction and metabolic disturbances to AD. Although cannabidiol (CBD) ha…
STUDY DESIGN: Multicenter Secondary Analysis. PURPOSE: To assess psychometric properties of a short-form Thai Version of the Spine Oncology Study Group Outcomes Questionnaire (TH-SOSGOQ-8D) among Thai patients. OVERVIEW OF LITERATURE: Altho…
Abstract Obesity-associated alterations in pulmonary function have been inconsistently identified by spirometry in pediatric populations. Impulse oscillometry (IOS) offers sensitive detection of peripheral airway resistance, yet data remain…
Background/Objectives: Periductal fibrosis (PDF) is a common hepatobiliary abnormality associated with chronic Opisthorchis viverrini infection and may represent an ultrasonographic marker of chronic biliary injury in liver fluke-endemic re…
Despite a declining trend, early childhood caries (ECC) remains a public health concern, particularly among very young children. In Thailand, ECC prevalence is consistently higher in provincial areas than in the capital city and remains und…
High Resolution Image Download MS PowerPoint Slide A continuous-flow, monophasic catalytic process for the direct production of 5-hydroxymethylfurfural (5-HMF) from sugarcane syrup was developed using a microreactor platform to enable susta…
Since little research has been conducted on the issues in intercultural communication (IC) in tourism with multimodality, this study examined the intercultural communicative competence (ICC) of Chinese tourists and Thai citizens pertaining …
A paper-based fluorometric sensor based on L-cysteine modified CdTe quantum dots (L-Cys-CdTe QDs) was developed for simple, cost-effective, and on-site detection of copper(II) ions (Cu(II)). The sensing platform was integrated with a smartp…
Multiple sclerosis (MS) arises from an autoimmune response in which the immune system erroneously targets myelin autoantigens within the central nervous system, leading to myelin degradation and subsequent neurological dysfunction. Identify…
Abstract Charcoal-rich surface hosts distinct, low-evenness microbiome. Nitrogen-fixing taxa peak in the nutrient-leaching layer. Sharp vertical shift from copiotrophs to oligotrophs with depth. Surface soils act as hotspots of methane and …
Purpose Social capital (SC) has attracted growing attention in family business (FB) research due to its critical role in value creation, business growth, and the sustainability of competitive advantages. This study provides a systematic and…
Journal
Journal of Small Business and Enterprise Development
Abstract Data from the placebo arm of DEN-301, a phase 3 trial of the TAK-003 dengue vaccine, were evaluated in this secondary post hoc analysis to assess dengue burden. Participants were aged 4–16 years from Asia Pacific and Latin America.…
Journal
Nature Health
Thai researchers
Chukiat Sirivichayakul
Thai institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
Introduction Health Technology Assessment (HTA) is widely used for evidence-informed priority setting in Thailand and has been integrated into pharmaceutical reimbursement decision-making through the National List of Essential Medicines (NL…
Objective: Prolonged sitting in office workplaces increases the risk of non-communicable diseases, work-related musculoskeletal disorders, and psychological health issues. This study evaluated the effectiveness of an office-based exercise p…
Knowledge of natural stone promoters in the urine was previously limited, but is essential to develop new targets for better management of calcium oxalate (CaOx) kidney stones. This work, therefore, unveils such information in the urine of …
Instructional leadership has, over time, become one of the most influential constructs in educational leadership and management research, policy, and practice. Yet its global diffusion has also produced conceptual drift, as the construct ha…
Openbill Storks are specialised snail eaters that forage in swamps and rice fields for freshwater snails. As swamps disappeared, they became rare in parts of their range, including Bangkok, Thailand, for many years. The arrival of invasive …
Slipper orchids (Paphiopedilum spp.) are classified as one of the most endangered orchid groups in Southeast Asia, mainly caused by habitat loss, overexploitation, and climate change. In order to establish a state of species’ conservation o…
Journal
WSEAS TRANSACTIONS ON ENVIRONMENT AND DEVELOPMENT
Thai researchers
Pichitporn Pholgerddee · Thamarat Phutthai · Sura Pattanakiat · Pisut Nakmuenwai · Thunyapat Sattraburut
PURPOSE: To investigate the clinical factors associated with biofilm formation in Candida tropicalis bloodstream infections and to evaluate its impact on patient mortality in a high-prevalence setting in Thailand. MATERIALS AND METHODS: We …
Background/Objectives The pre-analytical stability of electrolytes in capped whole blood at room temperature remains uncertain due to limited studies and inconsistent findings. This study investigates electrolyte stability during delayed ce…
Journal
Annals of Clinical Biochemistry International Journal of Laboratory Medicine
BACKGROUND: Thailand has experienced major shifts in food consumption patterns due to rapid socioeconomic development, urbanization, and globalization, with implications for population nutrition. However, empirical evidence on long-term pat…
Journal
Nutrition Journal
Thai researchers
Sumaira Zafar · Muhammad Umar · Warangkana Srichamnong · Rajesh Kumar · Sabri Bromage
High Resolution Image Download MS PowerPoint Slide Comprehensive phytochemical study of the whole plants of Aerides odorata yielded 21 compounds, including two new phenanthrene derivatives ( 1 – 2 ), one new inseparable enantiomeric aurone …
Journal
ACS Omega
Thai researchers
May Thazin Thant · Virunh Kongkatitham · Hnin Ei Ei Khine · Warisara Parichatikanond · Sanith Sri Jayashan
Thai institutions
Chulalongkorn University · Mahidol University · National Science and Technology Development Agency · National Electronics and Computer Technology Center
Abstract We analyze the evolution of climate change sentiment in firms over time and the role of independent directors using sentiment metrics developed by Sautner et al. (2023). These metrics, derived from advanced textual analysis of earn…
Nitrogen deficiency is a major constraint affecting rice productivity and grain quality; however, nutrient stress may also trigger metabolic reprogramming that enhances health-promoting compounds. The MT2 mutant, derived from KDML105, has b…
The degradation of soil resources in the southern region of Thailand, specifically the occurrence of severe acid sulfate soils (ASS), represents a multifaceted challenge that aligns with the conceptualization of a “wicked problem.” Such pro…
Journal
Asian Creative Architecture, Art and Design : ACAAD
Melioidosis is a life-threatening infectious disease caused by Burkholderia pseudomallei. Early and accurate diagnosis is critical for timely treatment and improved outcomes. Although highly endemic in tropical regions, it remains underdiag…
Journal
PLoS neglected tropical diseases
Thai researchers
Hasyanee Binmaeil · Thanakon Bunsong · Mary N. Burtnick · Paul J. Brett · Narisara Chantratita
Thai institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit · The Royal College Of Anesthesiologists Of Thailand
Prescribing patterns are highly influenced by national healthcare structures. This study aimed to investigate the current antidepressant prescribing patterns, associated diagnoses, and the impact of financial barriers on clinical decision-m…
BACKGROUND: Right ventricular outflow tract (RVOT) morphology may influence hemodynamics and suitability for transcatheter pulmonic valve implantation (PPVI) in patients with repaired tetralogy of Fallot (rTOF). METHODS: We retrospectively …
BACKGROUND: Cardiovascular autonomic dysfunction and respiratory muscle weakness have been detected in patients with COPD. Although low-intensity inspiratory muscle training over 12 weeks increases cardiac parasympathetic (vagal) activity, …
BACKGROUND: Unrecognized myocardial infarction (UMI) is associated with adverse outcomes and may occur in patients with obesity, who are at increased cardiovascular risk. Although cardiac magnetic resonance (CMR) enables accurate detection …
Background Neutrophils Extracellular Traps (NET) immobilize and kill extracellular pathogens. Aggregatibacter actinomycetemcomitans (Aa), associated with aggressive forms of periodontitis, has been shown to induce NET release. However, it r…
BACKGROUND: The Mindray BS-800 chemistry analyzer (Mindray Bio-Medical Electronics) has a hemolysis index (HI) function and is a candidate method for detecting free hemoglobin (fHb). This study aimed to validate the HI on the Mindray BS-800…
Background Dementia care requires not only clinical competence but also a high level of empathy from nursing professionals. Resilience has increasingly been recognized as a critical factor in enhancing both competence and compassionate care…
OBJECTIVE: To determine the effect of albumin-based fluid resuscitation on mortality in adults with septic shock. DESIGN: Systematic review and dual frequentist-Bayesian meta-analysis of randomised clinical trials (RCTs), following PRISMA g…
The presence of pesticide residues (organophosphates, carbamates, pyrethroids) in vegetables is a significant public health concern in Thailand. This study investigated the risk of pesticide residues exposure from vegetables in rapidly expa…
hepatocellular carcinoma (HCC) is the most common primary liver cancer and remains difficult to treat in advanced stages because of tumor heterogeneity and an immunosuppressive microenvironment. Chimeric antigen receptor (CAR) T-cell therap…
Malaria is responsible for more than half a million deaths each year. Parenteral artesunate is the recommended first-line treatment for severe malaria, but prompt treatment is often delayed affecting patient outcomes. Rectal artesunate is r…
Journal
Scientific Reports
Thai researchers
Joel Tarning
Thai institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
Asymptomatic Plasmodium vivax infections sustain transmission and derail elimination efforts, yet these hidden reservoirs evade current diagnostics. Here, we integrated computational immunology with empirical serology to discover high-perfo…
Estimates of preventable antimicrobial resistance (AMR) burden are important to inform local, national, regional, and global policies, targets and research priorities. Such estimates rely heavily on model assumptions and several analytical …
Journal
Nature Communications
Thai researchers
Cherry Lim · Sue J. Lee · Yin Mo · Ben S. Cooper
Thai institutions
Mahidol Oxford Tropical Medicine Research Unit · Mahidol University
Background Malaria remains a leading global health threat, primarily in sub-Saharan Africa. In Tanzania, malaria continues to cause high morbidity and mortality, especially in rural areas. Animal-keeping, common in these regions, may influe…
