A PRISMA-guided review searches four databases and groups AI for urodynamics into parameter-, raw-signal- and image-based approaches. Small datasets, bias and limited external validation prevent a conclusion that these tools are deployment-…
HDAC3 is highly expressed in colorectal cancer (CRC) and associated with poor prognosis. This study reveals that HDAC3 deletion dually regulates chemokine expression through epigenetic mechanisms, promoting CD8⁺ T cell infiltration (via CXC…
The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.
Journal
Journal of the European Academy of Dermatology and Venereology
Thai researchers
Daniel Fernandes Melo · Anne Kelly Leroy · Cintia Medeiros Martins
Nigropunctata is an understudied genus of bambusicolous fungi, and its diversity in Thailand remains poorly known. This study aimed to investigate species of Nigropunctata associated with bamboo in Thailand using morphological observations …
Journal
Nordic Journal of Botany
Thai researchers
Zaw Lin Tun · Digvijayini Bundhun · Kevin D. Hyde
Thai institutions
Mae Fah Luang University · Thai Health Promotion Foundation
BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and neuronal loss. Evidence links gut-brain axis dysfunction and metabolic disturbances to AD. Although cannabidiol (CBD) ha…
Background: Electrolyte disturbances are common in critically ill patients with acute kidney injury (AKI) and often require urgent intervention. Arterial blood gas (ABG) analyzers provide rapid point-of-care electrolyte measurements, but th…
STUDY DESIGN: Multicenter Secondary Analysis. PURPOSE: To assess psychometric properties of a short-form Thai Version of the Spine Oncology Study Group Outcomes Questionnaire (TH-SOSGOQ-8D) among Thai patients. OVERVIEW OF LITERATURE: Altho…
Abstract Obesity-associated alterations in pulmonary function have been inconsistently identified by spirometry in pediatric populations. Impulse oscillometry (IOS) offers sensitive detection of peripheral airway resistance, yet data remain…
Background/Objectives: Periductal fibrosis (PDF) is a common hepatobiliary abnormality associated with chronic Opisthorchis viverrini infection and may represent an ultrasonographic marker of chronic biliary injury in liver fluke-endemic re…
Objective: To determine the diagnostic accuracy of antenatal ultrasonographic fetal lung volume (FLV) for predicting neonatal respiratory distress syndrome (RDS) and to identify clinically relevant sources of heterogeneity. Methods: A syste…
Background Clinical constraints often limit nursing students' independent decision-making in pediatric settings. This study evaluated the effectiveness of simulation-based learning (SBL) on pediatric nursing knowledge and clinical decision-…
OBJECTIVE: To compare intermediate diastolic velocity (IDV) measurements, as well as E/IDV and A/IDV ratios, between fetuses affected and unaffected by Hb Bart's disease. METHODS: Fetuses at risk of Hb Bart's disease between 17 and 22 weeks…
Background: Recovery after abdominal aortic aneurysm surgery often involves prolonged functional decline and various postoperative complications. Structured nursing interventions during the perioperative period may help patients regain inde…
Rare subtypes of gastroesophageal malignancies represent a small but biologically meaningful fraction of upper gastrointestinal cancers. Although most therapeutic algorithms are derived from conventional squamous cell carcinoma and adenocar…
Background Secondary alveolar bone grafting (SABG) is essential for correcting alveolar defects in patients with cleft lip and palate. While clinical evaluation combined with 2-dimensional (2D) radiography is a practical and cost-effective …
Background Population-level epidemiological data on paediatric hepatobiliary diseases (HBD) are limited in Southeast Asia. We aimed to quantify national trends in healthcare utilisation, expenditure, and admission-based mortality associated…
Abstract Data from the placebo arm of DEN-301, a phase 3 trial of the TAK-003 dengue vaccine, were evaluated in this secondary post hoc analysis to assess dengue burden. Participants were aged 4–16 years from Asia Pacific and Latin America.…
Journal
Nature Health
Thai researchers
Chukiat Sirivichayakul
Thai institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
ABSTRACT Fungal peritonitis is a severe complication of peritoneal dialysis (PD), increasingly involving rare yeasts that challenge routine diagnostics. We report PD-associated peritonitis caused by Blastobotrys adeninivorans , initially mi…
BACKGROUND: Canine vector-borne pathogens (CVBPs) are increasingly relevant, particularly those of zoonotic concern, due to climate change and increased animal mobility. However, there is no information on the actual burden of these infecti…
BACKGROUND: Endoscopic spine surgery (ESS) is increasingly recognized for its clinical efficacy and patient-centered advantages, including reduced morbidity and faster recovery. However, despite growing global interest, its adoption remains…
Journal
The International Journal of Spine Surgery
Thai researchers
Vit Kotheeranurak
Thai institutions
Chulalongkorn University · King Chulalongkorn Memorial Hospital
Introduction Health Technology Assessment (HTA) is widely used for evidence-informed priority setting in Thailand and has been integrated into pharmaceutical reimbursement decision-making through the National List of Essential Medicines (NL…
Abstract: Prediabetes, defined by impaired glucose regulation, is an increasingly prevalent metabolic disorder with implications beyond glycemic control. Its impact on bone remodeling and healing is gaining attention, particularly in orthog…
Chalcones from medicinal plants are attractive starting points for anticancer lead discovery, and this study aimed to improve the anti-NSCLC potential of 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone (DMC) from Syzygium nervosum through…
BACKGROUND: Disaster settings pose substantial challenges to health-care delivery while simultaneously offering distinctive experiential learning opportunities for medical students. Exploring how students reflect on participation in psychia…
Introduction Breast ultrasound imaging is valuable for its non-invasiveness and cost-effectiveness but presents diagnostic challenges from speckle noise and limited contrast. Conventional CNN pooling methods compromise between noise reducti…
Background: H2 gas inhalation has been proposed as a selective modulator of reactive oxygen species (ROS), potentially mitigating treatment-related oxidative damage. This study investigated the effects of adjunctive H2 gas inhalation on ser…
Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two main neurodegenerative diseases and cause disability and death in patients worldwide. Neurodegeneration is characterized by a progressive loss of neuronal function and struct…
BackgroundEvidence on the feasibility of integrating music therapy into routine post-stroke aphasia rehabilitation in real-world settings remains limited.ObjectiveTo examine the feasibility of integrating a structured music therapy protocol…
This umbrella review aimed to synthesize and critically appraise high-level evidence on the effectiveness of digital health interventions across the chronic kidney disease (CKD) continuum, encompassing predialysis, dialysis, and kidney tran…
This study investigates the intricate interrelationships among drug abuse beliefs (DAB), drug craving of patients (DCP), and refusal self-efficacy (RSE) in individuals undergoing methadone maintenance treatment (MMT). It establishes a theor…
OBJECTIVE: Access to audiological services and support for individuals with hearing loss varies widely across low- and middle- income countries (LMICs) and high-income countries (HICs). This study examines disparities in the availability of…
Introduction: Lassa fever (LF) is a severe viral haemorrhagic disease caused by Lassa virus (LASV) and remains endemic in Nigeria, where it is associated with recurrent outbreaks, substantial morbidity, and high mortality. The persistence o…
Journal
Journal of Interventional Epidemiology and Public Health
Study Design: Randomized controlled trial. Purpose: This trial aimed to evaluate the efficacy and safety of a thermosensitive poloxamer-based anti-adhesive hydrogel in patients undergoing full-endoscopic lumbar discectomy for lumbar disc he…
Anthropology in One Health refers to the use of anthropological concepts, methods and field-based approaches to analyse health problems at the intersections of humans, animals, plants, microbes and environments. It examines how disease, ris…
Recent mycological surveys in Northern Mindanao, Philippines, have uncovered two morphologically distinct, previously undescribed species of Ophiocordyceps ( Hypocreales : Ophiocordycipitaceae ). Using an integrative framework that combines…
Journal
New Zealand Journal of Botany
Thai researchers
Janet Jennifer Luangsa-ard
Thai institutions
National Science and Technology Development Agency
Background Modern biomedical research excels at validating hypotheses but often struggles with conceptual discovery. The emphasis on statistical significance has fostered a culture of measurement without mechanism—abundant evidence, yet lim…
Background: Autologous platelet-rich fibrin (PRF) is a fraction of blood with a high concentration of platelets and multiple growth factors. Its application has shown promising results in wound care. However, it remains controversial whethe…
Vestibular disorders significantly impair postural stability and elevate fall risk, necessitating the use of validated assessment tools. While the Mini-Balance Evaluation Systems Test (Mini-BESTest) is a comprehensive measure of balance, di…
Background: Colon cancer remains a major cause of morbidity and mortality worldwide. Emergency surgical presentations, such as obstruction or perforation, are associated with poorer outcomes compared to elective surgery. This study aimed to…
Abstract Background HIV-associated tuberculosis is a leading cause of mortality. Mycobacterium tuberculosis bloodstream infection (MTB-BSI) is complicated by diagnostic difficulty and severe illness. We assessed whether MTB-BSI continues to…
BACKGROUND: The United Nations Organization (UNO) has proposed achieving specific Sustainable Development Goals (SDGs), including poverty, hunger, health, education, equality, climate change, and the need for sustainable development, while …
Parkinson's disease (PD) is the fastest-growing neurodegenerative disorder worldwide, with projections exceeding 25 million people by 2050. Its burden, however, is unevenly distributed. Many low- and middle-income countries face rapidly ris…
Journal
Journal of Parkinson s Disease
Thai researchers
Roongroj Bhidayasiri
Thai institutions
Thai Red Cross Society · Chulalongkorn University · King Chulalongkorn Memorial Hospital · The Royal College Of Anesthesiologists Of Thailand
Objective: Cranial surgery is associated with significant postoperative pain. Opioids are commonly used to provide pain relief. However, their use can lead to unwanted consequences, including neurological deterioration and respiratory depre…
Olextra, a processed hydroxytyrosol-rich olive pomace, is a by-product of olive oil industry and can be applied as a feed additive to improve shrimp health. This study aimed to evaluate the effect of Olextra on the growth, resistance to Vib…
Background/Objectives: Postoperative pulmonary complications (PPCs) are a major source of morbidity following cardiac surgery, particularly in older adults. While malnutrition is linked to adverse outcomes, the optimal screening tool for id…
PURPOSE: To investigate the clinical factors associated with biofilm formation in Candida tropicalis bloodstream infections and to evaluate its impact on patient mortality in a high-prevalence setting in Thailand. MATERIALS AND METHODS: We …
Background/Objectives The pre-analytical stability of electrolytes in capped whole blood at room temperature remains uncertain due to limited studies and inconsistent findings. This study investigates electrolyte stability during delayed ce…
Journal
Annals of Clinical Biochemistry International Journal of Laboratory Medicine
Highly contagious viral pathogens—such as porcine reproductive and respiratory syndrome, classical swine fever, and African swine fever—continue to pose serious threats to the swine industry and cause major global economic losses. Conventio…
Malnutrition is a common and clinically significant complication in patients with chronic kidney disease (CKD), contributing to increased morbidity and mortality. However, evidence regarding its prevalence and associated factors in pre-dial…
Background This study explores the lived experiences of individuals recovering from COVID-19, aiming to deepen understanding of their meaning-making processes and inform supportive responses in future health crises. Methods Fifteen particip…
Journal
F1000Research
Thai researchers
Ekuma Imkome · Kamonchanok Moonchai
Thai institutions
Asia Pacific International University · Thai Red Cross Society
Arundo donax is a gramineous plant with economic value and green energy potential. However, the fungal resources of A. donax have rarely been explored. In 2025, fungi on A. donax were collected and isolated from wetlands in Jiangxi Province…
Abstract Coronary artery disease (CAD) is associated with a high burden of long-term adverse cardiovascular events. Traditional risk stratification relies primarily on left ventricular ejection fraction, a measure limited to systolic functi…
BACKGROUND AND AIMS: In patients with inflammatory bowel diseases (IBD), tumor necrosis factor antagonists (anti-TNFs) are frequently used alongside immunomodulators to improve treatment efficacy. While an increased risk of cancers with thi…
Background: Early ambulation (EA), mobilizing within 24 h, is a cornerstone of recovery after lumbar spine surgery. Clinical evidence suggests that EA is strongly associated with superior postoperative outcomes, including accelerated functi…
Melioidosis is a life-threatening infectious disease caused by Burkholderia pseudomallei. Early and accurate diagnosis is critical for timely treatment and improved outcomes. Although highly endemic in tropical regions, it remains underdiag…
Journal
PLoS neglected tropical diseases
Thai researchers
Hasyanee Binmaeil · Thanakon Bunsong · Mary N. Burtnick · Paul J. Brett · Narisara Chantratita
Thai institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit · The Royal College Of Anesthesiologists Of Thailand
Prescribing patterns are highly influenced by national healthcare structures. This study aimed to investigate the current antidepressant prescribing patterns, associated diagnoses, and the impact of financial barriers on clinical decision-m…
