Feline gammaherpesvirus 1 (FcaGHV1) is a recently identified member of the Gammaherpesvirinae detected in domestic cats; however, its tissue distribution and pathological relevance remain incompletely defined. This study investigated the lo…
Objectives: This study aimed to investigate the prevalence of oral lichen planus (OLP) among individuals with hepatitis C virus (HCV) infection in upper northern Thailand and the potential association between OLP and HCV infection. Methods:…
Objectives: This study aimed to compare the mandibular posterior available space between patients with skeletal Class I and skeletal Class III malocclusion. Methods: The retrospectively analyzed cone-beam computed tomography (CBCT) scans fr…
Aims: This case report aims to demonstrate an alternative treatment approach of a failed endodontically treated tooth (ETT) in a patient at risk of medication-related osteonecrosis of the jaw (MRONJ), in which conventional retreatment of al…
Objectives: To investigate the time-dependent changes in flexural strength, tensile strength, and surface hardness of Tera Harz TC-85 DAC (Direct Aligner Clear) aligners after manufacturing. Methods: The aligner specimens were fabricated us…
Ceramic brackets have become increasingly popular and are now widely used in orthodontic treatment because of their less noticeable and aesthetically pleasing appearance. However, conventional debonding of ceramic brackets can result in ena…
Controlling mAb N-linked glycosylation is essential for ensuring therapeutic safety and efficacy. Because culture supplements can differentially affect both glycosylation profiles and culture performance, empirical optimization is often nec…
Alveolar bone grafting (ABG) is a cornerstone of the multidisciplinary management of cleft lip and palate (CLP), restoring alveolar continuity and enabling dental rehabilitation. Orthodontic tooth movement (OTM) into grafted sites promotes …
Objective To identify the latent heterogeneous subtypes of burnout and emotional eating among Chinese clinical nurses, and to examine the predictive effects of monthly night shift frequency and years of work experience on subtype membership…
Background: Dental implants placement in long-standing edentulous areas often encounter the problem of alveolar height deficiency from gradual bone resorption over time. Therefore, vertical bone augmentation prior to implant placement would…
Oral leiomyomatous hamartoma (OLH) is a rare lesion characterized by abnormal growth, with smooth muscle tissue as the predominant component. It mainly presents on the midline region of both the dorsal tongue and the maxillary alveolar ridg…
Background: Artificial Intelligence (AI) is increasingly integrated into preclinical medical education. Despite rapid adoption, comparative data on student satisfaction, perceptions, learning preferences, and academic outcomes remain limite…
Cardiac distress is common, yet minimal support is available for nurse assessment of patients. We translated the Cardiac Distress Inventory (CDI) into Thai (CDI-Thai) and evaluated its psychometric properties. This was a cross-sectional stu…
Invasive ventilation with oxygen supplementation may inadvertently cause ventilator- and hyperoxia-induced lung injury, respectively, but their balance is fairly unaddressed. The concept of mechanical power summarizes factors of ventilation…
Journal
American Journal of Physiology-Lung Cellular and Molecular Physiology
Dengue virus (DENV) remains a major global health burden, with four antigenically distinct serotypes (DENV-1–4) posing a significant challenge for vaccine development. Dengue non-structural protein 1 (NS1) has been associated with additiona…
ABSTRACT Conventional blood culture is the gold standard for pathogen identification for patients with sepsis, but its lengthy turnaround time—encompassing initial bottle incubation and subsequent phenotypic testing—may delay appropriate th…
Objectives The prevalence of Autism Spectrum Disorder (ASD) has been steadily increasing, partly due to improved awareness and diagnosis. However, when parents should bring their children in to be screened has not yet been clearly communica…
Journal
International Journal of Developmental Disabilities
Canine monocytic ehrlichiosis (CME), caused by Ehrlichia canis, requires rapid, field-deployable diagnostics in endemic regions. This study developed and evaluated a recombinase polymerase amplification (RPA) assay for rapid isothermal dete…
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is rare in pediatric patients, whereas B-lymphoblastic leukemia/lymphoma (B-ALL) is a common childhood hematologic malignancy. The synchronous occurrence of these two distinct lymphoid …
Introduction: Despite the availability of the national clinical practice guideline (CPG) for croup treatment, adherence has not been evaluated in real-world settings. This study aimed to evaluate adherence to the national CPG for croup and …
Diagnosing skin diseases remains a clinical challenge due to the visual similarity among diverse dermatological conditions. This study presents a prototype deep learning–powered system for multi-class dermatological screening, implemented t…
Abstract Adenosine is a ubiquitous endogenous modulator that coordinates diverse physiological processes by binding to specific adenosine receptors (ARs). Among the four known AR subtypes, A2ARs and A2BRs are critical determinants of cardio…
Journal
ACS Pharmacology & Translational Science
Thai researchers
Warisara Parichatikanond · Ratchanee Duangrat · Narawat Nuamnaichati · Sarawuth Phosri · Hnin Ei Ei Khine
Thai institutions
Mahidol University · Kasetsart University · Srinakharinwirot University · Huachiew Chalermprakiet University
Abstract Despite extensive research on CBD, a comprehensive analysis of its rapidly evolving molecular understanding, clinical validation across diverse fields such as oncology and neurology, safety concerns, and dynamic global regulatory c…
Anti-tumor immunity relies on coordinated interactions between dendritic cells (DCs) and cytotoxic CD8⁺ T cells to eliminate malignant cells. Mixed lineage kinase domain-like protein (MLKL), a key executioner of necroptosis, has recently be…
Cellular senescence is a root cause of aging and age-related disease. Senescent cells persist in tissues, secreting inflammatory factors that fuel inflammaging and immune decline. At the subcellular level, mitochondrial dysfunction has beco…
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer with limited therapeutic options once it reaches metastatic stages. While immune checkpoint inhibitors like avelumab have improved outcomes, achieving a complete and du…
Panduratin A (Pan-A) is a bioactive prenylated chalcone found in the rhizomes of Boesenbergia rotunda (fingerroot). It has various pharmacological properties, including anticancer, anti-inflammatory, antibacterial and antiviral activity. In…
Although enhanced recovery after surgery (ERAS) has demonstrated benefits in various surgical specialties, evidence supporting its application in elective glioma craniotomies remains limited. This study compared the institutional ERAS pathw…
OBJECTIVE: To evaluate the success rates of radioactive iodine therapy (RAIT) with fixed activity of 10mCi and 15mCi in pediatric patients with Graves' disease (GD). SUBJECTS AND METHODS: dose of RAIT by fixed activity regimen, either 10mCi…
BACKGROUND: Depressive and anxiety symptoms (depression and anxiety hereafter), and suicidality are common among psychiatric patients. This study examined the network structure of depressive and anxiety symptoms and suicidality among psychi…
China has abundant bamboo resources, among which Yunnan Province is one of the regions with the greatest number of species. The unique natural and geographic advantages provide an excellent environment for fungal growth. This study collecte…
This study delineated acute thermal thresholds in common carp Cyprinus carpio (39.9 ± 5.27 g; 13.54 ± 0.67 cm) by integrating physiological (cortisol, hematology, serum biochemistry, opercular movement) and molecular (HSC70-2) responses to …
Coniochaeta is a cosmopolitan fungal genus found in diverse habitats worldwide. During an investigation of microfungi from rock and soil samples collected in northern Thailand between 2024 and 2025, six strains of Coniochaeta were isolated.…
Background/Objectives: Campylobacter spp. are leading causes of foodborne gastroenteritis, and small-scale poultry farms are important reservoirs of antimicrobial resistance (AMR). This study investigated the prevalence of Campylobacter spp…
Journal
Antibiotics
Thai researchers
Nguyễn Thị Mỹ Nhân · Phitchayapak Wintachai · Thotsapol Thomrongsuwannakij
Resistance to poly(ADP-ribose) polymerase inhibitors (PARPi) in high-grade serous ovarian cancer (HGSOC) is increasingly driven by non-genetic drug-tolerant dormant cell populations, yet the adaptive programs sustaining these cells remain p…
Anticancer peptides (ACPs) have emerged as promising therapeutic agents owing to their potential for selective targeting of cancer cells. KK12 (amino acid sequence: KWWSKLKKFWKK) is a modified peptide derived from black soldier fly larvae; …
Background/Objectives: Watercress (Nasturtium officinale R.Br.) is a glucosinolate-rich cruciferous vegetable with reported cardioprotective properties. However, previous human studies have relied on targeted clinical and biochemical biomar…
AIM: The low sensitivity of STRONGkids, a nutrition risk screening tool, was observed during its implementation in patient care services at a tertiary care hospital. The screening process improvement was performed to enhance its effectivene…
Abstract Introduction: Epidural steroid injections (ESIs) are commonly used for lumbosacral radicular pain, but clinical outcomes remain variable. Objective: This study aimed to identify predictive factors and determine short-term patient-r…
This study aimed to develop interpretable models of 1500 m freestyle performance by implementing symbolic regression using anthropometric, body composition, biomechanical and physiological variables from original data and derived synthetic …
Abstract Wheat germ glycoprotein (WGPII) exhibits immunomodulatory activity; however, its protective mechanisms against intestinal injury remain unclear. This study investigated WGPII effects in cyclophosphamide (CTX)-induced intestinal inj…
Early revisits to the emergency department (ED) are commonly used as a quality indicator and reflect challenges in discharge decision-making. Although the National Early Warning Score 2 (NEWS2) is widely used to detect clinical deterioratio…
Streptococcosis and edwardsiellosis caused by Streptococcus agalactiae and Edwardsiella tarda , respectively, are amongst the most economically devastating bacterial diseases in Nile tilapia ( Oreochromis niloticus ) aquaculture, compounded…
This study evaluated the potential of synergistically degraded low-molecular-weight chitosan (LMW-CS) as a functional feed additive to promote growth, antioxidant capacity, innate immunity, and disease resistance in Pacific white shrimp (Li…
Background/Objectives: Clariid catfishes are a cornerstone of Southeast Asian aquaculture, where intensive breeding and interspecific hybridization have significantly decreased genetic diversity. To address the limited understanding of grow…
Journal
Genes
Thai researchers
Phonemany Thammachak · Ton Huu Duc Nguyen · Rinrapat Nitipatpornpanya · Anh Huynh Luu · Edem Uduak Linus
Thai institutions
Kasetsart University · Sakon Nakhon Rajabhat University · Ubon Ratchathani University · Thaksin University
Adolescent pregnancy remains a significant global public health issue. Thailand enacted the Act on Prevention and Solution to the Adolescent Pregnancy Problem and implemented a public health policy that provides free long-acting reversible …
Objective: This study aimed to identify potential diagnostic and prognostic biomarkers in urinary extracellular vesicles (uEVs). Material and Methods: Urine samples (n=30) from patients representing four breast cancer (BC) subtypes—Luminal …
Epifoliar fungi represent a notable group of fungi that commonly inhabit the surfaces of leaves. They are typically recorded as saprobes, obligate parasites, or commensals, and although globally distributed, they are especially prevalent in…
Journal
Phytotaxa
Thai researchers
Asieh Vasighzadeh · Alireza Armand · Ruvishika S. Jayawardena · Kevin D. Hyde
ABSTRACT Research into the electric eel ( Electrophorus ) has focused on its production of high‐voltage electrical discharges for predation and defence, and its divergence from other fish species in terms of molecular activities. However, t…
Cisplatin is an effective platinum-based chemotherapeutic agent used to treat a variety of cancers. However, its clinical utility is limited by dose-dependent neurotoxicity, yet no approved neuroprotective strategy currently exists. Our int…
Anti-interferon-γ (IFN-γ) autoantibody (AAb)-associated adult-onset immunodeficiency (AOID) is an emerging disorder in East Asian adults characterized by severe opportunistic infections despite negative HIV status. The mechanisms driving an…
Human herpesvirus-8 (HHV-8) is an oncogenic herpesvirus that poses unique challenges in solid-organ transplantation. Although uncommon, HHV-8-associated diseases including Kaposi sarcoma (KS), multicentric Castleman disease (MCD), primary e…
Abstract This article aims to compare the flexural properties, fracture toughness, and fracture resistance of 3D-printed hybrid material (Varseosmile Crown plus, VS) at various build orientations versus milled hybrid materials (Cerasmart 27…
Accurate identification of Plasmodium species is essential for appropriate malaria management, particularly in cases of Plasmodium vivax (P. vivax), in which relapse prevention requires radical cure. A diagnostically challenging case of lat…
Journal
American Journal of Tropical Medicine and Hygiene
Thai researchers
Christen Rune Stensvold
Thai institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
Abstract Aberrant O-glycosylation is a prominent feature of cancer and contributes directly to multiple hallmarks of malignant transformation. Cancer-associated O-glycans include both truncated structures that are unique to mucin-type O-gly…
Background: Thai obstetric nurses follow WHO gestational weight gain (GWG) guidelines to prevent gestational diabetes mellitus (GDM). However, these Western-derived guidelines misclassify approximately 16% of Thai pregnant women, who carry …
Background and Aim: Swine production systems differ considerably in housing, nutrition, biosecurity, and environmental exposure, all of which may influence hepatic metabolism, immune function, and tissue architecture. Histological indicator…
BACKGROUND: Mitral valve prolapse (MVP) is a common cardiac condition that is generally benign, yet a subset of affected patients develop malignant ventricular arrhythmias and sudden cardiac death. Female sex and myocardial fibrosis detecte…
BACKGROUND: The purpose of this study was to identify key preoperative radiographic parameters and develop a predictive model for abnormal knee joint line obliquity (KJLO) following medial open-wedge high tibial osteotomy (MOWHTO) in patien…
Extracting transferable design knowledge from Discrete Element Method (DEM) simulations remains challenging in granular material handling. We develop an explainable surrogate framework for two solar-panel-recycling subsystems: a silo discha…
Journal
Machine Learning and Knowledge Extraction
Thai researchers
Suphatchakorn Limhengha · Supattarachai Sudsawat
Thai institutions
Prince of Songkla University · Suratthani Rajabhat University · King Mongkut's University of Technology North Bangkok
