Antenatal Fetal Lung Volume for Predicting Neonatal Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis of Diagnostic Accuracy
A seven-study diagnostic meta-analysis involving 900 pregnancies estimated antenatal ultrasound fetal-lung-volume sensitivity at 88%, specificity at 82%, and HSROC AUC at 0.93 for neonatal respiratory distress syndrome. Heterogeneity exceeded 75% and definitions and cut-offs varied, so FLV remains an exploratory adjunct rather than a stand-alone test.