Lactobacillus acidophilus abolishes oxalate-mediated renal epithelial barrier disruption and calcium oxalate monohydrate crystal adhesion to renal epithelial cells
In a renal epithelial cell model, sodium oxalate disrupted barrier integrity, reduced ZO-1 and increased annexin A2-mediated crystal adhesion. Co-culture with Lactobacillus acidophilus prevented these changes and reduced oxalate in artificial urine.