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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
Geospatial Agriculture and Environment89IMPACT SIGNAL
Regional model-validation evidence

GEDI–Sentinel Model Maps Northeast Thai Rubber at 82.63% Accuracy but Struggles With Young Plantations

This study mapped 2024 rubber distribution and age structure across Northeast Thailand using Random Forest in Google Earth Engine, combining Sentinel-1, Sentinel-2, vegetation indices, and a GEDI-trained canopy-height model. Three-class rubber mapping reached 82.63% overall accuracy and about 0.84 F1; three-group age classification reached 83.39%. Plantations older than seven years dominated and were classified more reliably than young stands. The output is a regional monitoring baseline, not an error-free parcel-level decision map.

Thai researchersSavittri Ratanopad Suwanlee · Muhammad Hanif · Surasak Keawsomsee · Kemin Kasa · Narissara Nuthammachot · Sarawut Ninsawat · Jantima Polpinij · Jaturong Som-Ard
Medical Education and Serious-Illness Care89IMPACT SIGNAL
Longitudinal training evidence

Advance-Care-Planning Training Raised Residents’ Knowledge From 7.74 to 8.65, but Had No Control Group

This mixed-methods evaluation tested an Advance Care Planning programme combining role-play, personal-value reflection, and two Circle of Learning sessions with an entire cohort of 50 first-year internal-medicine residents. Longitudinal analysis used 34 complete cases through 15 months, and 10 residents were interviewed. Knowledge rose from 7.74 to 8.65 out of 9, alongside several attitude and confidence improvements. Interviewees said role-play bridged theory and practice but identified a need for ongoing workplace support. The evidence concerns learner readiness, not observed conversation quality or patient outcomes.

Thai researchersThagoon Kanjanopas · Smuch Siramongkholkarn · Wanna Jarusomboon · Ekkapop Sittiwantana · Arisa Phochaisarn · Saipin Hathirat · Saran Thanapluetiwong
Public Health and Migrant Health92IMPACT SIGNAL
Evidence of global relevance

Migrant TB Patients Chose Months-Long Sanatorium Care to Pursue Cure Amid Cost, Transport, and Documentation Barriers

This multi-perspective qualitative study at the SMRU tuberculosis sanatorium in Mae Ramat, Tak Province, examined why migrants choose long residential treatment. It included 37 unique patients—33 who chose the sanatorium and four who chose community DOTS—plus five health workers. Three themes organized the findings: desire for cure, barriers to diagnosis and treatment, and community and organizational support.

Thai researchersJindaporn Wirachonphaophong · Hai Ti Ti · Nay Kaw Htoo · Kanjana Winyoorat · Cha Ba · San Soe · Suphak Nosten · Htet Ko Ko Aung · Sein Sein Thi · Francois Nosten
Public Health and Health Systems92IMPACT SIGNAL
Qualitative evidence for service design

Patients in South Ethiopia Know How to Manage Diabetes, but Drug Shortages and Costs Undercut Self-Care

This qualitative study examined diabetes self-care in three South Ethiopian hospital clinics. Its 21 participants comprised 12 adults with type 2 diabetes and nine healthcare providers. Patients described medication, diet, physical activity, foot care, and glucose monitoring as daily work negotiated against financial pressure, drug shortages, beliefs, food costs, limited support, and health-system constraints. Patients tended to foreground structural barriers, whereas providers placed more emphasis on knowledge and forgetting advice. Continued counselling, reliable medicines, and peer support emerged as priorities, but these are interview-derived design directions rather than tested interventions.

Thai researchersTemesgen Anjulo Ageru · Cua Ngoc Le · Apichai Wattanapisit · Charuai Suwanbamrung
International Journal of Qualitative Studies on Health and Well-beingRead analysis →
Forest Policy and Bioeconomy92IMPACT SIGNAL
Evidence of global relevance

Perspectives on the forest bioeconomy: insights of stakeholders from cases in Central Europe and the Mekong region

This comparative study examines how 336 purposively recruited respondents in Czechia, Slovakia, Thailand, Laos and Vietnam understand and assess the forest bioeconomy. Respondents generally reported stronger familiarity with sustainable forest management and the circular economy than with the bioeconomy itself. Perceptions also varied across country cases, particularly within the Mekong region. A binary logistic regression identified associations between high perceived implementation and country, age, education, understanding of policy aims, support for implementation and positive assessments of forest-industry implementation. These findings describe perceptions within the recruited sample rather than national populations, and the reported associations should not be interpreted as causal effects.

Thai researchersNopparat Kaakkurivaara · Alice Sharp · Prasit Wangpakapattanawong
One Health and Zoonotic-Disease Prevention92IMPACT SIGNAL
Formative evidence for One Health intervention design

Zoonotic Risk in Rural Nan Is Not Just Behavioural: Water Scarcity, Forest Change, and Food Systems Connect Five Interfaces

Researchers examined everyday practices and conditions that could enable cross-species transmission in four rural villages in Nan Province, organising findings into five interfaces: human–animal, human–environment, human-human, animal–animal, and animal–environment. The picture is not simply one of deficient knowledge. Animal contact, butchering and food preparation, water scarcity and contamination, waste, forest change, intensified agriculture, mixed-species proximity, and multilingual communication operate as a system. Community leaders and village health volunteers were viewed as trusted messengers. The study therefore recommends education that combines knowledge, skills, practical tools, and recognition of structural limits, but it neither completed nor evaluated the final intervention.

Thai researchersMonchai Phongsiri · Simaphon Tomklang · Theerayuth Labooth · Thanapat Chaibut · Pongsakon Jaruton · Kotthamon Chanprathad · Sarutaya Suphawatthanaphan · Hans Overgaard · Patcharin Lapanun
Circular Bioeconomy and Seafood Technology92IMPACT SIGNAL
Comprehensive narrative-review evidence

Crustacean By-Products Hold High-Value Compounds, but ‘Green’ Extraction Still Lacks LCA and Industrial Proof

This review compares conventional acid–alkali and solvent extraction with supercritical fluids, enzymatic hydrolysis, pulsed electric fields, ultrasound, cold plasma, microwave, high-pressure processing, and deep eutectic solvents for recovering bioactives from crustacean by-products. No technology is universally optimal: conventional methods retain advantages in simplicity and maturity, while emerging methods may reduce chemicals or better preserve product quality but face equipment, cost, energy, reproducibility, and pilot-scale constraints. The paper is therefore a map of options and evidence gaps, not proof that one technology is the ‘most sustainable.’

Thai researchersAkanksha R. Gautam · Soottawat Benjakul · Rattikarn Boonchoosri · Nilesh Nirmal · Avtar Singh
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
73IMPACT SIGNAL
Clinical Medicine

Parametric study of electrohydrodynamic flow and heat transfer in a wind tunnel using thermochromic liquid crystals and smoke tracing

Scientific Reports

Thailand-affiliated authors
K. Wongcharee · D. Chutrakul · V. Chuwattanakul · S. Eiamsa-ard
Institutions
Mahanakorn University of Technology · King Mongkut's Institute of Technology Ladkrabang
73IMPACT SIGNAL
Clinical Medicine

Evidence- and opinion-based consensus from Delphi round 1 of the Asian aplastic anemia recommendation development

International Journal of Hematology

Thailand-affiliated authors
Surapol Issaragrisil
Institutions
Siriraj Hospital · Mahidol University
73IMPACT SIGNAL
Clinical Medicine

Severe fever with thrombocytopenia syndrome complicated by invasive pulmonary aspergillosis and septic shock: a case report highlighting the role of mNGS

Frontiers in Medicine

Thailand-affiliated authors
Mingzhi Fan
Institutions
Police General Hospital
73IMPACT SIGNAL
Environmental Engineering

Biphasic Oxidative Carboxylation of Aliphatic Olefins With H 2 O 2 to Produce Useful Cyclic Carbonates

Advanced Synthesis & Catalysis

Thailand-affiliated authors
Surajchaya Kheawmuan · Suthida Kaewsai · Wuttichai Natongchai · Pipat Na Ranong · Silvano Del Gobbo · Valerio D’Elia
Institutions
Vidyasirimedhi Institute of Science and Technology
73IMPACT SIGNAL
Clinical Medicine

Multifactorial influences on lung function in farmers: personal, occupational, and health-related factors

Journal of Environmental Science and Health Part B

Thailand-affiliated authors
Patchareeya Amput · Ajchamon Thammachai · Saisunee Konsanit · Patcharin Phrompao · Sirima Wongphon
Institutions
University of Phayao
73IMPACT SIGNAL
Environmental Engineering

A novel multi-criteria group decision-making technique in traffic flow and safety assessment using interval-valued complex spherical fuzzy soft set

Scientific Reports

Thailand-affiliated authors
Saalam Ali · Hamza Naveed
Institutions
King Mongkut's University of Technology Thonburi
73IMPACT SIGNAL
Clinical Medicine

Exploring the Reasons Behind the Low Purchase Rate of CPAP Machines Among Adult Patients With Obstructive Sleep Apnea Through Qualitative Research

Social Marketing Quarterly

Thailand-affiliated authors
Bundit Sawunyavisuth · Darunee Jongudomkarn · Kittisak Sawanyawisuth
Institutions
Khon Kaen University
73IMPACT SIGNAL
Environmental Engineering

Preharvest temperature treatments influence physiological traits, secondary metabolites, and volatile compounds in holy basil under controlled environment conditions

Scientific Reports

Thailand-affiliated authors
P. Boonkorkaew · Niafnan Hayi-asan · Akira Thongtip · Wannida Sae-Tang · Atikorn Panya · Natthaporn Phonsatta · Sujichon Thangvichien · Prapussorn Yingcharoen · Panita Chutimanukul
Institutions
Kasetsart University · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
73IMPACT SIGNAL
Environmental Engineering

Nationwide and regional evidence on PM2.5-mortality in a tropical climate: Risks persist below standard and under climate extremes

Ecotoxicology and Environmental Safety

Thailand-affiliated authors
Phichet Khunthong · Panuwat Vittayapraparat · Sitthichok Puangthongthub
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Two Mechanisms One Molecule: Developing a ‘Truly’ Bifunctional Degrader Targeting Rpn13 and CRBN

Journal of the American Chemical Society

Thailand-affiliated authors
Cody A. Loy · Shawn E. Vinogradsky · Darci J. Trader
Institutions
Mahidol University
73IMPACT SIGNAL
Multidisciplinary

CD163+ perivascular macrophages in schizophrenia: a research framework for testing macrophage-related mechanisms

Frontiers in Psychiatry

Thailand-affiliated authors
Chavit Tunvirachaisakul · Michael Maes
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Efficacy and safety of intrathecal morphine compared to peripheral nerve blocks in patients underwent foot and ankle surgery:  A propensity score analysis

F1000Research

Thailand-affiliated authors
Preeyaphan Arunakul · Prapasri Kulalert · Marut Arunakul
Institutions
Thammasat University
73IMPACT SIGNAL
Global Public Health

Histological development of the stomach and hepatopancreas of two laboratory-reared sesarmid crabs, Episesarma species (Decapoda: sesarmidae)

Discover Developmental Biology

Thailand-affiliated authors
Chanyut Sudtongkong · Supparat Kong-oh · Piyamat Kongtueng · Anan Kenthao · W. Tongtako · Narit Thaochan · Supapong Imsonpang · Sinlapachai Senarat
Institutions
Rajamangala University of Technology Srivijaya · Chiang Mai University · Naresuan University · Prince of Songkla University
73IMPACT SIGNAL
Global Public Health

Beyond Temporary Sobriety: The Association Between Sobriety Campaign Completion and Intention to Quit Alcohol

International Journal of Environmental Research and Public Health

Thailand-affiliated authors
Nittaya Srisuk · Manolee S. Penpong · Paithoon Sonthon · Udomsak Saengow
Institutions
Rajamangala University of Technology · Suratthani Rajabhat University · Phetchabun Rajabhat University · Walailak University
73IMPACT SIGNAL
Multidisciplinary

Enhanced dichloroacetonitrile degradation via VUV/PS: radical contributions, matrix interference, and energy considerations

Sustainable Environment Research

Thailand-affiliated authors
Somphong Soontharo · Supitchaya Jenjaiwit · Pradabduang Kiattisaksiri · Sumana Siripattanakul-Ratpukdi · Thunyalux Ratpukdi
Institutions
Khon Kaen University · Thammasat University · Lampang Rajabhat University · Lampang Hospital
73IMPACT SIGNAL
Clinical Medicine

Peripheral Nerve Cross-Sectional Area in Healthy Thai Children: Reference Values for Clinical Neuromuscular Ultrasound

Journal of Clinical Neurophysiology

Thailand-affiliated authors
Tanitnun Paprad · Jakkrit Amornvit · Chernkhuan Stonsaovapak · Kamin Naothaworn · Nath Pasutharnchat · Tunchanok Paprad
Institutions
Chulalongkorn University · King Chulalongkorn Memorial Hospital
73IMPACT SIGNAL
Environmental Engineering

Stage-resolved coordination of ion homeostasis, proton transport, and redox regulation supports saline-alkaline tolerance and yield stability in rice

Journal of Plant Physiology

Thailand-affiliated authors
Thanakorn Wangsawang · Marisa Yaemsaray · Itsarapong Budjun · Natta Phadungsil · Kamonthip Jiadkong · Sumana Wangsawang
Institutions
Srinakharinwirot University · Rajamangala University of Technology Suvarnabhumi · Maharat Nakhon Ratchasima Hospital · Nakhon Ratchasima Rajabhat University · Nakhon Sawan Rajabhat University · Thaksin University
73IMPACT SIGNAL
Environmental Engineering

Extreme rainfall trends and return periods under CMIP6 scenarios in Southern Thailand

Water Science

Thailand-affiliated authors
Ketvara Sittichok · Kittiwet Kuntiyawichai · Raweepohn Narudeesri-utai
Institutions
Kasetsart University · Khon Kaen University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link