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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,037 analyses
Clinical Medicine77IMPACT SIGNAL
Evidence of global relevance

Distinct genomic landscape of colorectal signet ring cell carcinoma reveals frequent KMT2 family alterations and SMAD4 inactivation

Targeted profiling of 517 cancer genes in 39 colorectal signet-ring cell carcinomas found KMT2C and SMAD4 alterations in 49% each, while canonical drivers such as APC and KRAS appeared less often than typically reported in conventional adenocarcinoma. This points to epigenetic and TGF-β hypotheses but does not yet guide treatment.

Thai researchersKrittiya Korphaisarn · Jirapat Aiamsophon · Nuttapong Ngamphaiboon · Napat Angkathunyakul · Ananya Pongpaibul · Ekkapong Roothumnong · Charuwan Akewanlop · Manop Pithukpakorn
Environment and Engineering77IMPACT SIGNAL
Evidence of global relevance

Leakage-Aware Transfer Learning with Explainable AI and CPU-Efficient Deployment for Mango Leaf Disease Classification on the MangoLeafBD Benchmark

After detecting duplicate and near-duplicate MangoLeafBD images before group-aware splitting, EfficientNetB0 achieved 99.50% accuracy and weighted F1 on a 599-image test set, with grouped cross-validation averaging 99.63%. CPU latency averaged 25.3 ms per image. Performance is strong on the benchmark but unproven in real orchards and new regions.

Thai researchersWirapong Chansanam · Suparp Kanyacome
Digital Health77IMPACT SIGNAL
Evidence of global relevance

Feature extraction from real-world polysomnography reports of obstructive sleep apnea cohort using large language model

DBNet/EasyOCR converted image-based Thai hospital polysomnography reports to text, followed by task-specific ChatGPT-3.5 extraction. Prompt refinement reduced errors and showed potential for real-world evidence workflows, but numerical, symbol and encoding errors remained common and clinically consequential. The abstract gives no sample size or accuracy estimates.

Thai researchersBikal Shrestha · R Sr Wabina · Pawin Numthavaj · Visasiri Tantrakul · Ammarin Thakkinstian
Clinical Medicine77IMPACT SIGNAL
Evidence of global relevance

Choosing the Platinum Partner in Advanced Biliary Tract Cancer: A Propensity Score–Matched Real-World Comparison of Gemcitabine Plus Carboplatin Versus Gemcitabine Plus Cisplatin

A real-world review of 154 advanced biliary-tract cancer patients compared GemCarbo (59) with GemCis (95). After propensity matching, median survival was 8.44 versus 11.63 months, HR 1.26 (95% CI 0.84-1.90), without statistical significance. The wide interval supports consideration when cisplatin is unsuitable, not equivalence.

Thai researchersJirapat Wonglhow · Patrapim Sunpaweravong · Chirawadee Sathitruangsak · Arunee Dechaphunkul · Panu Wetwittayakhlang
Engineering64IMPACT SIGNAL
Evidence of global relevance

Global Fixed-Time Synchronization of Fractional-Order Dual-Split-Quaternion Valued Memristive Neural Networks: Full Proofs and 6D Relativistic Image Encryption

A Maejo University mathematics study introduces dual-split-quaternion algebra for fractional-order memristive neural networks, proves synchronization within an initial-condition-independent fixed upper time, and uses hyperchaotic states in a 6D colour-image encryption construction. Its main contribution is theoretical; it does not certify production-grade cryptographic security.

Thai researchersGrienggrai Rajchakit
Basic science65IMPACT SIGNAL
Evidence of global relevance

Long‐term adverse cardiovascular changes induced by cocoa shell extract administration through lactation in fetal undernourished and control rats

A rat experiment tested lactation as a developmental reprogramming window by giving dams, whose offspring had or had not experienced fetal undernutrition, cocoa-shell extract at 250 mg/kg/day. Although adult undernourished offspring had lower blood pressure, several groups developed adverse cardiac function, vascular relaxation and arterial-wall changes.

Thai researchersMetee Iampanichakul
Environment and engineering65IMPACT SIGNAL
Evidence of global relevance

Weed Seed Detection in Plant Quarantine: Practices and Emerging Molecular Technologies

This review surveys weed-seed detection in plant quarantine, from morphology and germination to DNA-based tools. Dormancy, resemblance to crop seed and zero-tolerance thresholds make detection difficult. Molecular methods may reduce ambiguity, but require reference libraries, performance validation and workable port-of-entry workflows.

Thai researchersKittisak Buddhachat
Basic science65IMPACT SIGNAL
Evidence of global relevance

Two new species and one new record of Perennicordyceps (Polycephalomycetaceae, Hypocreales) from China

Researchers describe two new Perennicordyceps species and one new host record from China using morphology and multilocus phylogeny across nrLSU, ITS, nrSSU, tef-1α, rpb1 and rpb2. The new taxa formed supported lineages and expand knowledge of insect- and fungus-associated members of the genus.

Thai researchersKevin D. Hyde
Social science65IMPACT SIGNAL
Evidence of global relevance

Semantic Extension and Grammaticalization of SAME in Korean Sign Language (KSL) and Korean

A linguistic comparison traces semantic extension and grammaticalisation of SAME in Korean Sign Language and kath- in spoken Korean. Both move from identity toward correctness, evidential inference and mitigation, while spoken Korean extends to similarity and KSL does not because an iconic SIMILAR sign already occupies that function.

Thai researchersSeongha Rhee
Clinical medicine65IMPACT SIGNAL
Evidence of global relevance

Exploring the potential of cognitive intra-individual variability in HIV care and research in adults with HIV: a concept analysis

A Rodgers evolutionary concept analysis examined 22 articles to clarify cognitive intra-individual variability, or inconsistency in one person's cognitive performance, in adults with HIV. IIV may be sensitive to change beyond some mean scores, but it is not yet a diagnostic test and has no ready clinical cut-off.

Thai researchersHathaichanok Phaowiriya
Digital health65IMPACT SIGNAL
Evidence of global relevance

EPECT: An Eigenvalue-Guided Positional Encoding Classification Transformer for Cross-Subject EEG-fNIRS Decoding

EPECT combines convolution, positional encoding and eigenvalue-guided attention to classify motor-imagery and cognitive tasks from EEG-fNIRS. Across two public datasets under leave-one-subject-out evaluation, reported accuracies ranged from 96.3% to 98.1%, with ablation and integrated-gradients analyses. These were research datasets, not real rehabilitation patients.

Thai researchersChayut Bunterngchit
Energy and materials65IMPACT SIGNAL
Evidence of global relevance

Effect of hybrid nano-fillers on the mechanical, thermal and viscoelastic properties of epoxy-based polymer composites for progressive applications

Epoxy composites containing a total of 1 wt% silica, alumina and carbon black at 1:1, 1:4 and 4:1 ratios, with surface-treated fillers, showed up to an 18°C rise in glass-transition temperature and a 22-42°C rise in the 5% degradation temperature. These remain laboratory-coupon results.

Thai researchersBaranitharan Paramasivam · Malinee Sriariyanun
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

3,510records
3,510 records
77IMPACT SIGNAL
Digital Health

AIoT-Based Energy-Efficient Temperature Regulation for Closed-System Greenhouses Using Classification-Based Control

ECTI Transactions on Computer and Information Technology (ECTI-CIT)

Thailand-affiliated authors
Mashida Dangsalae · Attasuntorn Traisuwan · Apidet Booranawong · Kiattisak Sengchuai · Dujdow Buranapanichkit · Nattha Jindapetch
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Multidisciplinary

Structure-Guided Optimization of a LipL32-Targeting DNA Aptamer through Molecular Dynamics and Free-Energy Analysis

ACS Omega

Thailand-affiliated authors
Tri Cao Vu · Boonchoy Soontornworajit · Pichayanoot Rotkrua · Jiraporn Arunpanichlert · Cong Quang Vu · Yuthana Tantirungrotechai
Institutions
Thammasat University
77IMPACT SIGNAL
Multidisciplinary

Bioinformatics-Driven Identification of Flooding-Tolerance Genes and Their Structural and Molecular Characterization in Soybean

ACS Omega

Thailand-affiliated authors
Supaporn Baiya · Methee Juntaropakorn · Sunan Kitjaruwankul · Malinee Promkatkaew
Institutions
Kasetsart University
77IMPACT SIGNAL
Energy and Materials

Integrated Strategy for Sustainable Outdoor Photo-Fermentative Biohydrogen Production: Sequential Optimization, Repeated-Batch Operation, Modular Bioreactor Simulation, and Biomass Valorization

Energies

Thailand-affiliated authors
Netchanok Punriboon · Polson Mahakhan · Khomsorn Lomthaisong · Kowit Suwannahong · Kandasamy Bhuvaneswari · Surachai Wongcharee · Ravinan Chaiyates · Jutaporn Sawaengkaew
Institutions
Khon Kaen University · Burapha University · Mahasarakham University
77IMPACT SIGNAL
Clinical Medicine

Machine learning‑based classification of renal cell carcinoma and upper tract urothelial carcinoma using preoperative hematological markers

Biomedical Reports

Thailand-affiliated authors
Kanrapee Nuwatkrisin · Chanita Panwoon · Kiartisak Senchan · Sakkarn Sangkhamanon · Wunchana Seubwai
Institutions
Khon Kaen University · Vongchavalitkul University
77IMPACT SIGNAL
Clinical Medicine

Extraction Optimization and Preliminary Neuroprotective Evaluation of Asiaticoside and Asiatic Acid from Centella asiatica (L.) Urb Using In Vitro and In Silico Approaches

International Journal of Molecular Sciences

Thailand-affiliated authors
Chaiyasit Winyuchakhrit · Sarin Tadtong · Chatchapong Tangjidapichai · Weerasak Samee
Institutions
Srinakharinwirot University
77IMPACT SIGNAL
Clinical Medicine

Rapid simultaneous detection of katG S315T and rpoB S531L mutations for molecular screening of multidrug-resistant tuberculosis using a dual LAMP-lateral flow assay

Microbiology Spectrum

Thailand-affiliated authors
Jutturong Ckumdee · Somchai Santiwatanakul · Nakarin Vutipow · Thongchai Kaewphinit
Institutions
Navamindradhiraj University · Vajira Hospital · Srinakharinwirot University · Kasetsart University
77IMPACT SIGNAL
Clinical Medicine

High diversity and novel host associations of bat haemosporidian parasites in Cambodia: insights from a nationwide bat survey and multilocus analyses

Parasites & Vectors

Thailand-affiliated authors
Awatsaya Pimsai
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Chronic Erosive Dermatopathy (CED) Associated with Ectoparasite Infestation in Nile Tilapia Post-Larvae (Oreochromis niloticus Linnaeus, 1758)

Veterinary Sciences

Thailand-affiliated authors
Pornpawit Tanpichai · Onanong Charoenwai · Sayamon Srisuwatanasagul · Patharapol Piamsomboon
Institutions
Mahanakorn University of Technology · Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Sesamin Attenuates Interleukin-1β-Induced Inflammation in Human Synovial Cells: Involvement of the Nrf2/HO-1 Pathway and NLRP3 Expression

ACS Omega

Thailand-affiliated authors
Benjawan Wudtiwai · Atitaya Wayupat · Aitthiphon Chongchai · Prachya Kongtawelert · Peraphan Pothacharoen · Thanyaluck Phitak
Institutions
Chiang Mai University · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Possible Links Between PM2.5-Induced NLRP3 Inflammasome Activation and Its Role in Lung Cancer Progression and Drug Resistance

International Journal of Molecular Sciences

Thailand-affiliated authors
Thanaphat Worawichitchaikun · Pitchapa Wantanachaisaeng · Teerapat Teeppaibul · Prasit Suwannalert
Institutions
Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Serum FTIR spectral features associated with HDRA-defined gemcitabine sensitivity in cholangiocarcinoma

Biomolecules and Biomedicine

Thailand-affiliated authors
Kanokporn Matra · Patutong Chatchawal · Molin Wongwattanakul · Patipat Rachawangmuang · Sutthiwan Janthamala · Thanaphong Rattanathip · Sirinart Chio‐Srichan · Chanchai Hongsa · Malinee Thanee · Supakan Amontailak · Juthamas Jaimanee · Piyapong Simtong · Anchalee Techasen
Institutions
Khon Kaen University · Synchrotron Light Research Institute
77IMPACT SIGNAL
Clinical Medicine

Image-derived conjunctival hyperemia and clinical ocular surface changes after initiation of topical glaucoma therapy: a prospective longitudinal pilot study

Scientific Reports

Thailand-affiliated authors
Linda Hansapinyo · Nicha Pianwichanpong · Kessara Pathanapitoon · Chanut Hansapinyo · Nutt Hansapinyo · Pichaya Kulniwatcharoen · Karn Patanukhom
Institutions
Chiang Mai University · Rangsit University
77IMPACT SIGNAL
Clinical Medicine

Predictors of the need for airway adjuncts during mask ventilation in Thai adult patients undergoing general anesthesia: A prospective observational study

PLoS ONE

Thailand-affiliated authors
Orarat Karnjanawanichkul · Chanikarn Nuanthong · Ngamjit Pattaravit · Wirat Wasinwong · Sawitree Sricharoenpongchai · Anongluk Samakkee
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Efficacy and safety of tocilizumab for refractory postsurgical cystoid macular edema

Journal of Ophthalmic Inflammation and Infection

Thailand-affiliated authors
Prapatsorn Ongpalakorn
Institutions
Nopparat Rajathanee Hospital
77IMPACT SIGNAL
Multidisciplinary

A Hierarchical Computer Vision Framework for Continuous Dairy Cow Behavior Monitoring in an Obstructed Free-Stall Barns

Smart Agricultural Technology

Thailand-affiliated authors
Aqeel Raza · Kumail Abbas · H. Hogeveen · Chaidate Inchaisri
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Metabolomic and lipidomic analyses reveal phosphatidylcholine–lysophosphatidylcholine axis alterations in sorafenib-persistent hepatocellular carcinoma

Biomedicine & Pharmacotherapy

Thailand-affiliated authors
Meng Chieh Yang · Nichawadee Sandech · Sucheewin Krobthong · Likit Rangsirattanakul · Wisuit Pradidarcheep · Arnatchai Maiuthed
Institutions
Srinakharinwirot University · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Patient safety events and outcomes in brain tumor surgery : A retrospective cohort study

Journal of Neurosciences in Rural Practice

Thailand-affiliated authors
Kanisorn Sungkaro · Pannawit Chumchue · Thara Tunthanathip · Supaporn Sainamsai
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Development and evaluation of a drug–herb interaction alert system integrated into a hospital electronic health record

Pharmacia

Thailand-affiliated authors
Thanatcha Songmuang · Ananya Songmuang · Chonladda Pitchayajittipong · Teeraporn Sadira Supapaan
Institutions
Warin Chamrap Hospital · Ubon Ratchathani University
77IMPACT SIGNAL
Clinical Medicine

Association of adipocyte hypertrophy and ultrasound severity score in lymphedematous limb: a cross-sectional study

Scientific Reports

Thailand-affiliated authors
Parkpoom Piyaman · Panitta Sitthinamsuwan · Sirin Apichonbancha · Nutcha Yodrabum
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Phosphoprotein-enriched proteomics identifies heat shock cognate 71 protein as a host factor supporting chikungunya virus replication in macrophages

Scientific Reports

Thailand-affiliated authors
Nattaya Kamchompoo · Songkran Thongon · Artittaya Athipanyasilp · Tipparat Thiangtrongjit · Kawin Chantima · Onrapak Reamtong · Kobporn Boonnak
Institutions
Siriraj Hospital · Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
77IMPACT SIGNAL
Clinical Medicine

Multidisciplinary providers’ perspectives on timely predialysis arteriovenous access preparation: An exploratory mixed-methods study in upper Northern Thailand

PLoS ONE

Thailand-affiliated authors
Amaraporn Rerkasem · Kochaphan Phirom · Pak Thaichana · Prit Kusirisin · Puntapong Taruangsri · Suwinai Saengyo · Sasinat Pongtam · Wanicha Pungchompoo · Kittipan Rerkasem
Institutions
Chiang Mai University · Nakornping Hospital · Maharaj Nakorn Chiang Mai Hospital
77IMPACT SIGNAL
Clinical Medicine

Lung Function-Based Assessment of Small Airway Dysfunction in Chronic Respiratory Diseases

Biology

Thailand-affiliated authors
Chalerm Liwsrisakun · Athavudh Deesomchok · Chaicharn Pothirat · Warawut Chaiwong
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Baseline characteristics and practice patterns in geriatric vs. non-geriatric hemodialysis patients: initial results from a Thai nationwide multicenter prospective cohort (Thai-HDcohort)

Renal Failure

Thailand-affiliated authors
Wanjak Pongsittisak · Jeerath Phannajit · Wonngarm Kittanamongkolchai · Theerasak Tangwonglert · Thawee Chanchairujira · Kraiwiporn Kiattisunthorn · Kornchanok Vareesangthip · Bongkod Surattichaiyakul · Arkom Nongnuch · Surachet Vongsanim · Pantipa Tonsawan · Pornpen Sangthawan · Siribha Changsirikulchai · Phanupong Phutrakool · Peerapat Thanapongsatorn · Pichaya Tantiyavarong · Talerngsak Kanjanabuch · Khajohn Tiranathanagul · Suchai Sritippayawan · Suree Yoowannakul · Vuddhidej Ophascharoensuk · Paweena Susantitaphong
Institutions
Navamindradhiraj University · Chulalongkorn University · King Chulalongkorn Memorial Hospital · Phramongkutklao Hospital · Siriraj Hospital · Rajamangala Institute of kidney disease · Mahidol University · Ramathibodi Hospital · Chiang Mai University · Khon Kaen University · Prince of Songkla University · Srinakharinwirot University · Thammasat University · Bhumibol Adulyadej Hospital
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link