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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,037 analyses
Maternal Metabolic Health77IMPACT SIGNAL
Prospective biomarker cohort evidence

First-trimester plasma asprosin and its association with gestational diabetes mellitus: A prospective cohort study

This prospective cohort enrolled 302 low-risk singleton pregnancies at 10–14 weeks, measured plasma asprosin, and assessed gestational diabetes at 24–28 weeks. Ninety-eight participants (32.5%) developed GDM. Asprosin varied with BMI but did not discriminate later GDM, with an AUC of 0.516. The study provides a first-trimester reference range and evidence against using this biomarker alone for early screening.

Thai researchersSathaphone Inthavong · Phudit Jatavan · Sirinart Kumfu · Nipon Chattipakorn · Theera Tongsong
Diabetes and Complications77IMPACT SIGNAL
Local case-control evidence

Factors associated with microvascular complications in patients with type 2 diabetes in Mueang District, Phitsanulok Province

A hospital-based case-control study in Mueang Phitsanulok compared 130 patients with physician-diagnosed microvascular complications and 260 controls. Diabetes for at least seven years, blood pressure of 140/90 mmHg or higher and high stress were associated with complications. The extremely large association for no metformin use had a very wide CI and cannot establish a direct protective drug effect.

Thai researchersNathamon Kamolvoradej · Patipat Vongruang · Sakesun Thongtip · Kongprai Tunsuchart
Mental Health and Family Caregiving85IMPACT SIGNAL
Instrument development and validation evidence

Psychometric Validation of a Family Adaptation Measure for First-Episode Psychosis

Researchers developed a culturally grounded measure of family adaptation and caregiving role engagement in Thai first-episode psychosis. Focus groups with 17 caregivers, item development and piloting preceded validation in 343 caregivers from four psychiatric hospitals, split into EFA (171) and CFA (172) groups. The 23-item, four-dimension FACRI explained 68.71% of variance and had overall Cronbach's alpha of 0.94. This is preliminary validity evidence, not a diagnostic test or proof of patient benefit.

Thai researchersWilai Napa · Nantiya Ekathikhomkit · Pennapa Unsanit · Patraporn Bhatarasakoon
Water, Sediment and the Mekong Basin77IMPACT SIGNAL
Catchment-scale modelling framework

A hydrological-year stratified regionalization framework for sediment rating curves in the largest tributary of the Mekong River

In the Mun River Basin, the Mekong's largest tributary, researchers developed a sediment-rating-curve regionalisation framework for sparse monitoring conditions. Flood, normal and drought years were separated before comparing regression and catchment-similarity approaches. Sediment-discharge behaviour varied by hydrological condition, while the preferred method depended on slope and erosion-related catchment attributes, arguing against a single static curve for every place and year.

Thai researchersNantawoot Inseeyong · Pavisorn Chuenchum · Kwanchai Pakoksung · Jeerapong Laonamsai
Malaria and Vaccine Development73IMPACT SIGNAL
Sequence and computational prediction evidence

Mapping HLA-restricted T-cell epitopes within conserved regions of Plasmodium vivax circumsporozoite protein from Thailand

PvCSP sequences from 34 P. vivax-infected patients in Southern Thailand were compared with 281 public sequences from Brazil and Vanuatu. IEDB predictions mapped T-cell epitopes against prevalent Thai HLA alleles. Conserved N- and C-terminal regions contained dense CD4+ and CD8+ targets, and cumulative modelled population coverage reached 95.86% in Southeast Asia. These are vaccine-design candidates, not observed immunogenicity or protection.

Thai researchersPongsakorn Thawornpan · Sasicha Suksapan · Thiranai Kitingen · Piyawan Kochayoo · Pachara Tianpothong · Patchanee Chootong
Crop Protection and Agricultural Bioproducts72IMPACT SIGNAL
Laboratory antagonism and preliminary toxicity evidence

Antagonistic Activity and Preliminary Toxicity Assessment of a Bacillus subtilis TU089 Bioproduct Against Phytophthora palmivora Causing Durian Root and Stem Rot

Five Bacillus strains were screened against Phytophthora palmivora MNP13, which causes durian root and stem rot. B. subtilis TU089 inhibited growth by 76.56±0.23% on plates and was developed into an encapsulated product at about 10^8 CFU/mL that retained activity comparable to fresh cells. Cell assays yielded IC10 values of 1,090 µg/mL in MRC-5 and 309.82 µg/mL in HaCaT cells; acute oral testing found no significant adverse effects under the studied conditions. Efficacy remains laboratory-based and safety preliminary.

Thai researchersPonchanok Datmanee · Apipu Ariyachayut · Thunyatorn Yimsoo · Dusit Athinuwat · Wilawan Chuaboon
Malaria and Adjunctive Treatment82IMPACT SIGNAL
Phase I safety and dose evidence

Sevuparin in children with severe malaria: a phase I safety and dose-finding trial

A phase I trial in Kenyan and Zambian children hospitalised with severe malaria tested adjunctive sevuparin as three infusions at 0, 8 and 16 hours. Twenty-three children were enrolled and 20 were included in the primary analysis. Model-guided escalation and dose-limiting APTT prolongation led to a maximum tolerated dose of 3 mg/kg per infusion. This is an early safety and dose-finding result, not evidence of clinical efficacy.

Thai researchersNicholas P. J. Day · Arjen M. Dondorp
Air Pollution and Health85IMPACT SIGNAL
Provincial observational time-series evidence

Health risks and lag effects of ambient PM2.5 exposure on respiratory and cardiovascular mortality and morbidity in Ratchaburi, Thailand

Using a distributed lag non-linear model, the study linked ambient PM2.5 with respiratory and cardiovascular mortality and morbidity in Ratchaburi during 2015–2019, from the exposure day through seven subsequent days. Across all ages and genders, each 10 µg/m³ increase was associated with 5.42% higher respiratory mortality at lag 0 and 2.69% higher respiratory morbidity over lag 0–6.

Thai researchersSitthipong Pengjan · Sébastien Bonnet · Savitri Garivait
Maternal Health and High-Risk Pregnancy77IMPACT SIGNAL
Multi-hospital case-control evidence

Predictors of preeclampsia with severe features: A multi-center analysis of maternal and health system factors in Thai tertiary hospitals

Across four Thai tertiary hospitals, a case-control study compared 156 postpartum women with preeclampsia: 52 with and 104 without severe features, alongside data from 111 nurse-midwives. After adjustment for antenatal visits and gravidity, prior preeclampsia was associated with 5.99-fold higher odds of severe features. Moderate knowledge and higher BMI showed inverse associations, which should not be treated as causal protection.

Thai researchersTippawan Boonyaporn · Piyanun Limruangrong · Ameporn Ratinthorn · Thitipong Tankumpuan
Ethnic Health and Non-Communicable Disease81IMPACT SIGNAL
Grounded-theory qualitative evidence

Balancing tradition, modernity, and spirituality: A grounded theory of non-communicable disease management in the Tai Saek Ethnic Group of Thailand

A qualitative study of 18 Tai Saek adults from two Nakhon Phanom villages described NCD management as a non-linear negotiation among traditional lifeways, changing agriculture and diet, generational relations, spirituality and biomedicine. Participants did not simply reject modern care; they selectively combined ancestor worship with clinical treatment. This could support cultural empowerment, while heavy reliance on rituals could delay biomedical care.

Thai researchersAmornrat Sangsaikaew · Wasana Ruaisungnoen
Cancer Supportive Care89IMPACT SIGNAL
Mixed-methods evidence synthesis

Experiences and coping strategies among cancer patients with cancer-related cognitive impairment treated with chemotherapy: a mixed-methods systematic review

This mixed-methods systematic review synthesized 21 studies of chemotherapy-treated cancer patients with cancer-related cognitive impairment. Memory, concentration, and executive-function problems affected daily life, work, relationships, and emotions. Coping included memory aids, self-regulation, task modification, lifestyle changes, and social support. Perceived benefit is not trial-proven clinical efficacy.

Thai researchersJing Li · Wasana Ruaisungnoen · Supan Unjai · Parichat Wonggom
Environment and Risk Management89IMPACT SIGNAL
Regional model-validation evidence

The Socio-Economic Asymmetry Index (SEA): A Framework for Identifying Vulnerability–Exposure Mismatch in Flood-Prone Agricultural Landscapes

This study introduces the Socio-Economic Asymmetry Index (SEA) to identify agricultural areas where socioeconomic vulnerability outweighs physical flood exposure. The framework was tested at 63,010 sampling points in Thailand's Upper Chi River Basin using satellite and land-use data, six composite indices, Random Forest, and SHAP. About one quarter of the study area fell into high or very high asymmetry classes. The result is a spatial modelling tool for prioritising field assessment and support; it does not establish which factors causally produce flood losses.

Thai researchersPatiwat Littidej · Jiradech Majandang · Benjamabhorn Pumhirunroj
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

3,510records
3,510 records
74IMPACT SIGNAL
Clinical Medicine

Ambient PM2.5 and respiratory tract disorder–related outpatient visits among healthcare workers: an ecological time-series study

BMC Public Health

Thailand-affiliated authors
Chaturon Tangsangwornthamma · Sivakorn Suntinipanon · Chathaya Wongrathanandha · Natnaree Aimyong
Institutions
Ramathibodi Hospital · Mahidol University
74IMPACT SIGNAL
Clinical Medicine

Clinical Prognostic Factors and Survival Risk Stratification for Advanced Biliary Tract Cancer Treated with Gemcitabine-Based Palliative Chemotherapy: A Real-World Retrospective Study

Life

Thailand-affiliated authors
Jirapat Wonglhow · Arunee Dechaphunkul · Patrapim Sunpaweravong · Chirawadee Sathitruangsak · Panu Wetwittayakhlang
Institutions
Prince of Songkla University
74IMPACT SIGNAL
Clinical Medicine

A Proteomic Study Reveals the Relationship Between Arterial Stiffness and Hyperglycemia in Middle-Aged Obese Men

Clinical Diabetology

Thailand-affiliated authors
Thanutchaporn Nutmakul · Nontawit Auppawat · Sittiruk Roytrakul · Jintana Sirivarasai · Sirasa Ruangritchankul · Wutarak Monsuwan
Institutions
Ramathibodi Hospital · National Science and Technology Development Agency
74IMPACT SIGNAL
Clinical Medicine

Skipjack tuna bone-derived biocalcium ameliorates osteoblast and osteoclast differentiation through microRNA21 regulation

iScience

Thailand-affiliated authors
Sompot Jantarawong · Sudarat Phuntong · Saowapak Kanobthammakul · Papitchaya Watcharanurak · Jidapa Szekely · Jedsada Kaewrakmuk · Eakolarn Chotianuson · Doungporn Amornlerdpison · Chutima S. Vaddhanaphuti · Theeraphol Senphan · Yutthana Pengjam
Institutions
Prince of Songkla University · Suan Sunandha Rajabhat University · Maejo University · Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Effects of Fine Particulate Matter on Systemic Inflammatory Biomarkers in Elderly Patients with Chronic Obstructive Pulmonary Disease Versus the Healthy Elderly: A Pilot Study

International Journal of Molecular Sciences

Thailand-affiliated authors
Warawut Chaiwong · Chalerm Liwsrisakun · Pilaiporn Duangjit · Juthamas Inchai · Chaiwat Bumroongkit · Athavudh Deesomchok · Theerakorn Theerakittikul · Atikun Limsukon · Pattraporn Tajarernmuang · Nutchanok Niyatiwatchanchai · Konlawij Trongtrakul · Chittrawadee Chitchun · Nipon Chattipakorn · Siriporn C. Chattipakorn · Nattayaporn Apaijai · Chaicharn Pothirat
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Abalone-derived dermatopontin and its RFK-containing peptide promote osteogenesis via TGF-β/Smad signaling pathway

International Journal of Biological Macromolecules

Thailand-affiliated authors
Purimpuch Soongnart · Supawich Boonkua · Orawan Thongsum · Rueangtip Chantunmapitak · Primwadee Wichienwat · Pan Soonsawad · Wattana Weerachatyanukul · Aungkura Supokawej · Somluk Asuvapongpatana
Institutions
Mahidol University · Thammasat University · Mahamakut Buddhist University
74IMPACT SIGNAL
Multidisciplinary

Nanoclay, calcium alginate, and composite soil amendments mitigate drought effects on wheat growth and water-use efficiency

Frontiers in Plant Science

Thailand-affiliated authors
Khalifa M. Alteneiji · Razan F. Alhammadi · Lamya Alsuwaidi · Walid Abo Baker · Mohammad A. Al-Faqieh
Institutions
Department of Livestock Development
74IMPACT SIGNAL
Clinical Medicine

Organic UV Filter Exposure in Children of Indonesia, Thailand, and Saudi Arabia – Urinary Concentrations, Risks, and Potential Sources

Integrated Environmental Assessment and Management

Thailand-affiliated authors
Kraichat Tantrakarnapa · Wissanupong Kliengchuay
Institutions
Mahidol Oxford Tropical Medicine Research Unit
74IMPACT SIGNAL
Clinical Medicine

Investigation of Oncogenic Gene Mutation and Associated Protein Expression in Ameloblastic Carcinoma

Oral Diseases

Thailand-affiliated authors
Puangwan Lapthanasupkul · Jintana Pankam · Siribang-on Piboonniyom Khovidhunkit · Prapapun Seneetuntigul · Nakarin Kitkumthorn
Institutions
Mahidol University · Ministry of Public Health · Burapha University
74IMPACT SIGNAL
Clinical Medicine

Late-follicular androgen and estrogen rise associated with clinical pregnancy in IVF/ICSI with granulosa cell studies

Reproduction and Fertility

Thailand-affiliated authors
Rungnapa Sririwichitchai · Chantacha Sitticharoon · Issarawan Keadkraichaiwat · Pailin Maikaew · Suchawadee Chanheng · Somsin Petyim
Institutions
Siriraj Hospital
74IMPACT SIGNAL
Clinical Medicine

Combined podocyte, fibrotic and echocardiographic correlates of an operationally defined subclinical cardiorenal phenotype in chronic kidney disease: an exploratory study

Renal Failure

Thailand-affiliated authors
Ulugbek Ochilov
Institutions
Asia Pacific International University
73IMPACT SIGNAL
Fundamental Science

L-shell X-ray production cross sections for thick silver targets induced by MeV Cuq+ ions with velocities well below the Ag L-shell Bohr velocity

Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms

Thailand-affiliated authors
J. Hussain · L.D. Yu · U. Tippawan
Institutions
Chiang Mai University · Thailand Center of Excellence in Physics
73IMPACT SIGNAL
Multidisciplinary

Effects of Reactive Footwork Training Versus Simple-Reaction Training on Lower-Extremity Motor Coordination, Dynamic Balance, and Cognitive Screening Scores in University Sport Science Students: A Pilot Randomised Controlled Trial

Sports

Thailand-affiliated authors
Arisa Sespheng · Kantapong Kaewmuan · Pitak Chaimiphak · Thanakrit Mekkeaw · Suttinee Petmunee · Saithip Piyatammakun · Thanatchaporn Putthikrittayakarn · Nurfajjaree Loteh · Natkanlaya Nonthanapapol
Institutions
Walailak University
73IMPACT SIGNAL
Multidisciplinary

PHOTOLUMINESCENCE AND SCINTILLATION PROPERTIES OF CE-DOPED Lu0.5Gd0.5AlO3 SINGLE CRYSTALS GROWTH BY FLOATING ZONE METHOD

Suranaree Journal of Science and Technology

Thailand-affiliated authors
Tharittawat Tharasook · Prom Kantuptim
Institutions
Kasetsart University
73IMPACT SIGNAL
Clinical Medicine

Evaluation of pyocin activity and pyocin-related gene distribution in multidrug- and extensively drug-resistant Pseudomonas aeruginosa isolates from Thailand

PeerJ

Thailand-affiliated authors
Phatcharin Laosena · Punthira Suppaiboolkij · Pornpavee Nualnisachol · Jiraphan Premsuriya
Institutions
Chulabhorn Royal Academy · Kasetsart University · Chulabhorn Graduate Institute · Chulabhorn Hospital
73IMPACT SIGNAL
Clinical Medicine

Foot Shape in Women With and Without Hallux Valgus Determined Using 3‐Dimensional Foot Scanning

Journal of Foot and Ankle Research

Thailand-affiliated authors
Hylton B. Menz
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Optimized Self‐Healing and Antioxidant Hydrogels Based on Gallic Acid–Blended Quaternized Chitosan and Oxidized Pectin for Potential Wound Dressing Applications

Journal of Biomedical Materials Research Part A

Thailand-affiliated authors
Porntipa Pankongadisak · Kitipong Kiti · Pimpakan Faijai · Mueanchan Chanmontri · Orawan Suwantong
Institutions
Mae Fah Luang University
73IMPACT SIGNAL
Multidisciplinary

Development of Indomethacin Nanostructure Lipid Carrier Incorporated in Emulgel

Journal of Health Science and Medical Research

Thailand-affiliated authors
Kanokwan Singpanna · Prasopchai Patrojanasophon · Chaiyakarn Pornpitchanarong · Nattanit Aekwattanaphol · Chanwit Changcharoensuk · Peerapat Chidchai
Institutions
Siam University · Silpakorn University · Prince of Songkla University
73IMPACT SIGNAL
Clinical Medicine

Dysregulation of the miR-29c-3p/collagen axis induces spermatogenic failure in heat stress and non-obstructive azoospermia

Asian Journal of Andrology

Thailand-affiliated authors
Shou‐Bo Zhang
Institutions
Police General Hospital
73IMPACT SIGNAL
Clinical Medicine

UHPLC/QTOF-mass spectrometry-based metabolomic analysis of Riceberry during simulated in vitro digestion

Acta Alimentaria

Thailand-affiliated authors
S. Punyauppa-Path · S. Phupaboon · W. Pilap · U. Thonsri · P. Kiatprasert · Patcharee Boonsiri
Institutions
Rajamangala University of Technology Isan, Surin Campus · Mahasarakham University · Thammasat University · Khon Kaen University
73IMPACT SIGNAL
Clinical Medicine

Caregiver Coaching in Occupational Therapy–Led Early Intervention: A Scoping Review

Child Care Health and Development

Thailand-affiliated authors
Krongporn Chinchai · Thapanee Panunpang · Chirathip Thawisuk · Rujira Jaikaew
Institutions
Chiang Mai University
73IMPACT SIGNAL
Engineering

Coupled effects of center-of-gravity position and added mass on vortex-induced vibration and galloping-based hydrokinetic piezoelectric energy harvesting

Applied Physics Letters

Thailand-affiliated authors
Patcharakon Siriyothai · Chartsiri Rujasiri · Chawalit Kittichaikarn
Institutions
Kasetsart University
73IMPACT SIGNAL
Global Public Health

Molecular detection and multilocus genotyping of Toxoplasma gondii in archived stray-cat fecal DNA from central and western Thailand

Veterinary World

Thailand-affiliated authors
Ruenruetai Udonsom · Aongart Mahittikorn · Supaluk Popruk
Institutions
Mahidol University
73IMPACT SIGNAL
Digital Health

Representation learning for low-data protein fitness prediction using sequence–structure embeddings and graph neural networks

Scientific Reports

Thailand-affiliated authors
Chanoknun Phunnasorn · Narupat Hongdilokkul · Wasakorn Laesanklang · Charin Modchang · Tipaluck Krityakierne
Institutions
Mahidol University · Centre of Excellence in Mathematics · Ministry of Higher Education, Science, Research and Innovation
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link