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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
Public Health74IMPACT SIGNAL
Evidence of global relevance

Severe Pregnancy-Associated Acute Kidney Injury and Maternal Vulnerability

Electronic records covering 4,094,111 US pregnancies showed severe pregnancy-associated acute kidney injury rising from 9.0 to 27.6 per 10,000 pregnancies between 2012-2013 and the COVID-19 era. Pre-existing cardiometabolic vulnerability was associated with risk, but observational data cannot separate infection, access, testing, and secular trends.

Thai researchersNattachai Srisawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Integrative hematological and transcriptomic analysis reveals monocyte alterations and molecular signatures of inflammatory-coagulation crosstalk in long COVID

A comparison of 21 people with long COVID and 24 asymptomatic controls found lower white-cell, monocyte, and platelet counts and longer APTT. Integrated with a separate public transcriptomic dataset, the findings support a proposed inflammation-coagulation model, but the small and non-identical datasets cannot establish mechanism.

Thai researchersParin Kamseng · Namngern Chantaramanee · Rittikorn Sompan · Sarayot Rareongjai
Public Health74IMPACT SIGNAL
Evidence of global relevance

Toxicological Assessment of Oligofructans Derived from Raw Sugar Fermentation by Bacillus subtilis TISTR 001 and Their Modulatory Effects on Rat Gut Microbiota

Thai researchers evaluated oligofructans produced from raw sugar using Bacillus subtilis TISTR 001. Rats showed no treatment-related mortality or toxicity at doses up to 2,000 mg/kg/day for 90 days, alongside reported shifts in gut microbial taxa. These are preclinical animal findings and do not establish human safety or benefit.

Thai researchersSirinya Taya · Boontiwa Ninchan · Sonthaya Umsumarng · Jutamat Klinsoda · Rawiwan Wongpoomchai · Charatda Punvittayagul
Environment and Engineering74IMPACT SIGNAL
Evidence of global relevance

A Multi-Frequency SAR Framework for Methane Emission Estimation in Thai Rice Paddies

A GISTDA-led framework combines Sentinel-1 and ALOS-2 radar with IPCC accounting to detect crop timing, classify water regimes, and estimate methane from irrigated rice in Thailand's central plain. Mean absolute error was 18.5 kg CH4/ha, but structural uncertainty in the IPCC Tier 1 emission factor exceeded all algorithmic errors combined.

Thai researchersNuntikorn Kitratporn · Kanjana Koedkurang · Panu Nueangjamnong · Kittiphop Simachokchai · Chompunut Chayawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Predictors of Early Recurrence and Survival Outcomes Following Curative Resection for Colorectal Liver Metastases and the Role of Salvage Surgery: A Retrospective Cohort Study

In a retrospective cohort of 109 patients undergoing liver resection for colorectal liver metastases, high tumor burden, major intraoperative blood loss, T3/T4 primary disease, and RAS mutation were associated with early recurrence. Selected patients undergoing salvage re-hepatectomy had favorable long-term survival, but small subgroups and strong selection bias prevent causal conclusions.

Thai researchersPipit Burasakarn · Nisanat Thongkua · Vachiraluck Chalokool · Anuparp Thienhiran · Sermsak Hongjinda · Pusit Fuengfoo
Mental Health74IMPACT SIGNAL
Evidence of global relevance

The Study of Efficacy and Safety of a Modified Chaihu Shugan San Formula in the Treatment of Insomnia Associated with Stress: A Pilot Clinical Evaluation

A 30-participant pre-post pilot reported lower sleep-quality and stress scores after four weeks of twice-daily modified Chaihu Shugan San, without clear liver or renal safety signals. Without randomization, a control group, or placebo, the study cannot separate the formula's effect from placebo, attention, or change over time.

Thai researchersPorwarut Srihara · Cao ZuoJun · Somratchanee Srifar · Mattanapat Phraecharoen
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Benefits of three consecutive sputum inductions using nebulized racemic salbutamol versus hypertonic saline in smear-negative or sputum-scarce pulmonary tuberculosis patients: a prospective randomized, double-blind study

In a randomized double-blind trial of 345 adults with suspected smear-negative or sputum-scarce pulmonary tuberculosis, three consecutive daily inductions with nebulized racemic salbutamol produced a higher combined smear-or-culture yield and fewer adverse events than 3% hypertonic saline. The single-center study evaluates specimen collection for diagnosis, not tuberculosis treatment outcomes.

Thai researchersWarangkana Keeratichananont · Suriya Keeratichananont · Natthaphon Ubonsutvanich · Jirachaya Chaisurote
Thai Fruit and Diabetic Retinal Mechanisms74IMPACT SIGNAL
Evidence of global relevance

ANTIOXIDANT AND ANTI-APOPTOTIC ACTIVITIES OF MAKIANG FRUIT EXTRACT IN ARPE-19 CELLS EXPOSED TO GLUCOSE-INDUCED CELLULAR DAMAGE

A 95% ethanol makiang-fruit extract showed antioxidant activity and, when co-administered in 30 mM glucose-exposed ARPE-19 cells, the highest 200 microgram/mL dose increased viability by 15.4%, reduced ROS by 37.8%, and lowered caspase-9 and -3 activities.

Thai researchersNuntaporn Chanpurk · Kemika Praengam · Angkalsiri Deeaum · Pasitta Panritdum · Monruedee Sukprasansap · Chawanphat Muangnoi
Green-Tea Compounds and Diabetic Kidney Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Epigallocatechin-3-gallate, l-theanine and theophylline abolish high-glucose-induced renal cell senescence and subsequent epithelial-mesenchymal transition and fibroblast activation via SIRT1/PGC-1α axis: Implications for diabetic kidney disease

High glucose induced senescence in proximal tubular cells, whose SASP-conditioned medium then triggered epithelial-mesenchymal transition in distal tubular cells and fibroblast activation. EGCG, L-theanine, and theophylline suppressed these effects while restoring SIRT1/PGC-1alpha signaling.

Thai researchersRattiyaporn Kanlaya · Sunisa Yoodee · Kanokwan Nonthawong · Chonicha Subkod · Supanan Nanthawuttiphan · Visith Thongboonkerd
Curcumin and Breast-Tumor Immunity74IMPACT SIGNAL
Evidence of global relevance

Curcumin Attenuates Breast Cancer Cell-induced Inflammasome Activation via the NOD-like receptor protein 3/Caspase-1/Interleukin-1β Axis

Breast-cancer-cell conditioned medium drove THP-1-derived macrophages toward a pro-inflammatory tumor-associated phenotype with higher IL-1beta, NLRP3, and caspase-1. Curcumin pretreatment reduced IL-1beta secretion, NLRP3 protein, and IL1B/CASP1 transcripts.

Thai researchersKhwandow Kunchana · Wattanased Jarisarapurin · Suvara K. Wattanapitayakul
Encephalitis Viruses and Cell-Death Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Inhibition of calpain-mediated BAX cleavage attenuates Japanese encephalitis virus-induced apoptosis in SH-SY5Y neuroblastoma cells

In SH-SY5Y cells, Japanese encephalitis virus activated calpain to cleave BAX into p18 BAX, which moved to mitochondria and triggered cytochrome c, caspase-3, PARP cleavage, and apoptosis. The calpain inhibitor calpeptin attenuated these signals and improved cell viability.

Thai researchersKuntida Kitidee · Arisara Samutpong · Nattaporn Pakpian · Montri Yasawong · Prapimpun Wongchitrat
Occupational Lung Health and AI Screening74IMPACT SIGNAL
Evidence of global relevance

Artificial neural network modelling using complete blood count for the early detection of black lung disease among Indonesian coal miner: A retrospective longitudinal study

Annual health data from 807 Indonesian coal miners followed from 2013-2021 showed 13.9% cumulative black-lung incidence. A complete-blood-count neural network and Cox model both identified eosinophils and monocytes as influential predictors.

Thai researchersKurnia Ardiansyah Akbar · Kraiwuth Kallawicha · Pallop Siewchaisakul
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
77IMPACT SIGNAL
Clinical Medicine

FACTORS ASSOCIATED WITH HOSPITAL ARRIVAL TIME IN ISCHEMIC STROKE PATIENTS AT BUDDHASOTHORN HOSPITAL: AN AMBISPECTIVE OBSERVATIONAL COHORT STUDY

Journal of Southeast Asian Medical Research

Thailand-affiliated authors
Sirinapa Saneemanomai · Phatchapong Rurgring · Thinnapat Ninthasuk · Juthatip Rooyoo · Jidaporn Burenoi · Neera Krasaesoontorn · Benjawan Saengluan · Nunnaphat Khantiviriyapanich · Kanokporne Nakboon
Institutions
Rajabhat Rajanagarindra University · Thammasat University Hospital
77IMPACT SIGNAL
Clinical Medicine

Metabolic and Inflammatory Risk Stratification in Resected Cholangiocarcinoma: A Retrospective Exploratory Analysis

Medical Sciences

Thailand-affiliated authors
Piya Prajumwongs · Attapol Titapun · Vasin Thanasukarn · Apiwat Jareanrat · Natcha Khuntikeo · Nisana Namwat · Poramate Klanrit · Arporn Wangwiwatsin · Jarin Chindaprasirt · Prakasit Sa-Ngiamwibool · Nattha Muangritdech · Sittiruk Roytrakul · Watcharin Loilome
Institutions
Khon Kaen University · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
77IMPACT SIGNAL
Clinical Medicine

Soluble C-type lectin LvLectin1 mediates recognition and agglutination of Ecytonucleospora hepatopenaei spores in Pacific white shrimp Litopenaeus vannamei

Aquaculture Reports

Thailand-affiliated authors
Warumporn Yingsunthonwattana · Kanokporn Bunyanam · Wisarut Junprung · Prakob Saman · Anchalee Tassanakajon
Institutions
Chulalongkorn University · Charoenkrung Pracharak Hospital
77IMPACT SIGNAL
Clinical Medicine

Three Decades of Outcomes in Pediatric Inborn Errors of Immunity in a Middle-Income Setting: Survival by IUIS Class and the Role of HSCT

Journal of Clinical Immunology

Thailand-affiliated authors
Chanunchida Watcharaporn · Usanarat Anurathapan · Suradej Hongeng · Samart Pakakasama · Wasu Kamchaisatian · Watcharoot Kanchongkittiphon · Wiparat Manuyakorn
Institutions
Mahidol University · Ramathibodi Hospital
77IMPACT SIGNAL
Clinical Medicine

Cooking-Induced Molecular Transformations in Foods: Matrix-Dependent Effects on Bioaccessibility, Metabolism, and Health

Food Reviews International

Thailand-affiliated authors
Muhammad Waqar
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

A rapid hybridization-free LAMP–LFB assay for the clinical detection of Neisseria gonorrhoeae in urine specimens

Scientific Reports

Thailand-affiliated authors
Jutturong Ckumdee · Somchai Santiwatanakul · Rossaphorn Kittiyaowamarn · Thongchai Kaewphinit
Institutions
Navamindradhiraj University · Vajira Hospital · Srinakharinwirot University · Ministry of Public Health
77IMPACT SIGNAL
Clinical Medicine

Effects of Ramadan Fasting on Intradialytic Hypoglycemia and Clinical Outcomes in Patients with Diabetes on Maintenance Hemodialysis: A Multicenter Prospective Cohort Study in Southern Thailand

Medical Sciences

Thailand-affiliated authors
Jayanton Patumanond · Moragot Chatatikun · Atthaphong Phongphithakchai
Institutions
Naresuan University · Walailak University · Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Diagnostic Performance of Six Tests for Helicobacter pylori Infection in Peptic Ulcer Bleeding: A Prospective Head-to-Head Comparison

Clinical and Translational Gastroenterology

Thailand-affiliated authors
Tanawat Geeratragool · Thanapat Atthakitmongkol · Supathep Tansirichaiya · Pubet Weeranawin · Somchai Leelakusolvong · Monthira Maneerattanaporn
Institutions
Siriraj Hospital
77IMPACT SIGNAL
Clinical Medicine

Epidemiology and mortality rate of thyroid storm in Thailand: Analysis using a national in-patient database

PLoS ONE

Thailand-affiliated authors
Jin Sothornwit · Suranut Charoensri · Dueanchonnee Sribenjalak · Chatlert Pongchaiyakul
Institutions
Khon Kaen University
77IMPACT SIGNAL
Global Public Health

Effectiveness of a hybrid practice-based training program for community-based elderly caregivers in Chiang Rai during the COVID-19 pandemic

Journal of Public Health and Development

Thailand-affiliated authors
Ananya Eusawat · Watcharapong Ruankham · Rawipat Pullap · Piyaporn Tamesak · Nattra Somkamlang
Institutions
Chiang Rai Rajabhat University
77IMPACT SIGNAL
Clinical Medicine

Gelatin Hydrolysate from Bigeye Snapper (Priacanthus tayenus) Skin Attenuates the Progression of Diabetic Nephropathy in Rats by Modulating Oxidative Stress, Inflammatory Responses, and Endoplasmic Reticulum Stress Signaling Pathways

International Journal of Molecular Sciences

Thailand-affiliated authors
Krit Jaikumkao · Khin Thandar Htun · Nattavadee Pengrattanachot · Prempree Sutthasupha · Sasivimon Promsan · Napatsorn Montha · Onanong Jaruan · Rarin Suriyalungka · Phassaraporn Khadtha · Sompong Sriburee · S. Kothan · Sutee Wangtueai · Anusorn Lungkaphin
Institutions
Chiang Mai University · Kasetsart University · University of Phayao
77IMPACT SIGNAL
Energy and Materials

Unlocking High-Valent Chalcogen Redox with Halide-Rich Electrolytes for High-Energy Lithium Batteries

Nature Communications

Thailand-affiliated authors
Jiaqian Qin
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Prediction model for survival outcome in patients with acute myeloid leukemia: a multicenter prospective cohort study from Thai Acute Leukemia Working Group

Frontiers in Oncology

Thailand-affiliated authors
Pirun Saelue · Jakrawadee Julamanee · Adisak Tantiworawit · Thanawat Rattanathammethee · Weerapat Owattanapanich · Smith Kungwankiattichai · Chantiya Chanswangphuwana · Chantana Polprasert · Wasithep Limvorapitak · Supawee Saengboon · Kannadit Prayongratana · Chantrapa Sriswasdi · Pimjai Niparuck · Teeraya Puavilai · Chajchawan Nakhakes · Chinadol Wanitpongpun
Institutions
Prince of Songkla University · Chiang Mai University · Siriraj Hospital · Chulalongkorn University · King Chulalongkorn Memorial Hospital · Thammasat University · Phramongkutklao Hospital · Ramathibodi Hospital · Rajavithi Hospital · Khon Kaen University
77IMPACT SIGNAL
Clinical Medicine

Immune response and durability of human papillomavirus antibodies in vaccinated adolescents after hematopoietic stem cell transplantation: a pilot study

BMC Infectious Diseases

Thailand-affiliated authors
Benjaporn Wangviboonchai · Phuwakrit Nithirungruang · Usanarat Anurathapan · Samart Pakakasama · Suradej Hongeng · Chompunuch Klinmalai · Nopporn Apiwattanakul
Institutions
Mahidol University · Ramathibodi Hospital
77IMPACT SIGNAL
Environmental Engineering

Culturable mycota from Karst caves in Yunnan Province, China

IMA Fungus

Thailand-affiliated authors
Xiang-Fu Liu · K. W. Thilini Chethana · Lu Li · Kevin D. Hyde · Wenhua Lu · Rui-Fang Xu · Xue-Mei Chen · Xian Zhang · Xing-Juan Xiao · Tian‐Ye Du · Nakarin Suwannarach · Jaturong Kumla
Institutions
Mae Fah Luang University · Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Association of Vitamin D Intake, VDR Levels, and Relevant Gene Polymorphisms in Early-Stage Thai Colorectal Cancer Patients Following Vitamin D3 Supplementation

Medical Sciences

Thailand-affiliated authors
Natthaporn Kuendee · Aunchana Rodrungnok · Kamphon Intharanut · Alisa Naladta · Oytip Nathalang · Sakda Daduang · Sophida Sukprasert
Institutions
Rajamangala University of Technology Tawan-ok · Thammasat University · Khon Kaen University
77IMPACT SIGNAL
Clinical Medicine

Expanding the Diversity of Penicillium in Thailand: New Records and Habitat—Substrate Associations

Phytotaxa

Thailand-affiliated authors
SUBASINGHA A.D. THAKSHILA · Chitrabhanu S. Bhunjun
Institutions
Mae Fah Luang University
77IMPACT SIGNAL
Global Public Health

HIV disclosure and stigma among couples in Muslim communities in Indonesia: a qualitative study

BMC Public Health

Thailand-affiliated authors
Eka Sari Ridwan · Sarunya Benjakul · Mondha Kengganpanich · Chanuantong Tanasugarn
Institutions
Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Ingredient characterization and preclinical evaluation of a standardized crude hydrolyzed yeast β-glucan preparation (crude-HBGs) derived from insoluble yeast β-glucans: Cerebrovascular outcomes in HFD/STZ-induced diabetic rats

Food Bioscience

Thailand-affiliated authors
Wipapan Khimmaktong · Nissara Lorthong · Abdulhakam Dumidae · Pannawich Sukprasirt · Rapepun Wititsuwannakul · Aratee Aroonkesorn · Thanawat Pitakpornpreecha
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

A study protocol of the additional human albumin during resuscitation in patients with surgical septic shock: A randomized controlled trial (the ALBumin Use in Surgical septic shock, ALBUS study)

Clinical Critical Care

Thailand-affiliated authors
Nattachai Hemtanon · Nuanprae Kitisin · Thassayu Yuyen · Nattaya Raykateeraroj · Patipan Toomtong · Prasert Sawasdiwipachai · Onuma Chaiwat · Annop Piriyapatsom · Karuna Wongtangman · Nonthida Rojanapithayakorn · Suchanun Lao-amornphunkul · Thirada Srinil · Napat Thikom · Chayanan Thanakiattiwibun · Paramet Bumroongsawat · Ornsuma Tansritrang · Julalak Sobha
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Blood metabolomes distinguish malnutrition and reflect treatment response in adult thalassemia patients: a randomized controlled trial

Scientific Reports

Thailand-affiliated authors
Chanisa Thonusin · Rattana Weerasathain · Pokpong Piriyakhuntorn · Supawan Buranapin · Thanawat Rattanathammethee · Sasinee Hantrakool · Chatree Chai‐Adisaksopha · Ekarat Rattarittamrong · Lalita Norasetthada · Nonthakorn Hantrakun · Teerachat Punnachet · Nuttanun Wongsarikan · Wichwara Nawara · Nipon Chattipakorn · Adisak Tantiworawit · Siriporn C. Chattipakorn
Institutions
Chiang Mai University · The Royal College Of Anesthesiologists Of Thailand
77IMPACT SIGNAL
Multidisciplinary

Knotless barbed suture is associated with fewer short-term cesarean scar defects compared with conventional suture in a randomized controlled trial

Scientific Reports

Thailand-affiliated authors
Supapun Wattanacharoen · Chada Burapasikarin · Wirun Thongchumnum · Kittisak Sawanyawisuth
Institutions
Vachira Phuket Hospital · Khon Kaen University
77IMPACT SIGNAL
Clinical Medicine

Neutropenia in adult patients with thalassemia receiving deferiprone: a 10-year experience from a large thalassemia cohort

Blood Research

Thailand-affiliated authors
Ploylarp Lertvipapath · Weerapat Owatanapanich · Waratchaya Uawattanasakul · Smith Kungwankiattichai
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Effects of Adding BreatheMAX-Assisted Deep Breathing to Home-Based Spot Marching on Maximal Voluntary Ventilation and Peak Expiratory Flow in Young Adults with Overweight or Obesity: A Randomized Controlled Trial

International Journal of Environmental Research and Public Health

Thailand-affiliated authors
Sujittra Kluayhomthong · Nontanat Sathaporn · Parkpoom Pipatbanjong · Umaporn Panpang · Kanyanat Kanka · Noppasorn Promman · Phanpan Inthajark · Sasit Sutawong · Pakhin Thamwiwat · Suntichai Prachumkhong · Vitsarut Buttagat
Institutions
Mae Fah Luang University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link