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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
Geospatial Agriculture and Environment89IMPACT SIGNAL
Regional model-validation evidence

GEDI–Sentinel Model Maps Northeast Thai Rubber at 82.63% Accuracy but Struggles With Young Plantations

This study mapped 2024 rubber distribution and age structure across Northeast Thailand using Random Forest in Google Earth Engine, combining Sentinel-1, Sentinel-2, vegetation indices, and a GEDI-trained canopy-height model. Three-class rubber mapping reached 82.63% overall accuracy and about 0.84 F1; three-group age classification reached 83.39%. Plantations older than seven years dominated and were classified more reliably than young stands. The output is a regional monitoring baseline, not an error-free parcel-level decision map.

Thai researchersSavittri Ratanopad Suwanlee · Muhammad Hanif · Surasak Keawsomsee · Kemin Kasa · Narissara Nuthammachot · Sarawut Ninsawat · Jantima Polpinij · Jaturong Som-Ard
Medical Education and Serious-Illness Care89IMPACT SIGNAL
Longitudinal training evidence

Advance-Care-Planning Training Raised Residents’ Knowledge From 7.74 to 8.65, but Had No Control Group

This mixed-methods evaluation tested an Advance Care Planning programme combining role-play, personal-value reflection, and two Circle of Learning sessions with an entire cohort of 50 first-year internal-medicine residents. Longitudinal analysis used 34 complete cases through 15 months, and 10 residents were interviewed. Knowledge rose from 7.74 to 8.65 out of 9, alongside several attitude and confidence improvements. Interviewees said role-play bridged theory and practice but identified a need for ongoing workplace support. The evidence concerns learner readiness, not observed conversation quality or patient outcomes.

Thai researchersThagoon Kanjanopas · Smuch Siramongkholkarn · Wanna Jarusomboon · Ekkapop Sittiwantana · Arisa Phochaisarn · Saipin Hathirat · Saran Thanapluetiwong
Public Health and Migrant Health92IMPACT SIGNAL
Evidence of global relevance

Migrant TB Patients Chose Months-Long Sanatorium Care to Pursue Cure Amid Cost, Transport, and Documentation Barriers

This multi-perspective qualitative study at the SMRU tuberculosis sanatorium in Mae Ramat, Tak Province, examined why migrants choose long residential treatment. It included 37 unique patients—33 who chose the sanatorium and four who chose community DOTS—plus five health workers. Three themes organized the findings: desire for cure, barriers to diagnosis and treatment, and community and organizational support.

Thai researchersJindaporn Wirachonphaophong · Hai Ti Ti · Nay Kaw Htoo · Kanjana Winyoorat · Cha Ba · San Soe · Suphak Nosten · Htet Ko Ko Aung · Sein Sein Thi · Francois Nosten
Public Health and Health Systems92IMPACT SIGNAL
Qualitative evidence for service design

Patients in South Ethiopia Know How to Manage Diabetes, but Drug Shortages and Costs Undercut Self-Care

This qualitative study examined diabetes self-care in three South Ethiopian hospital clinics. Its 21 participants comprised 12 adults with type 2 diabetes and nine healthcare providers. Patients described medication, diet, physical activity, foot care, and glucose monitoring as daily work negotiated against financial pressure, drug shortages, beliefs, food costs, limited support, and health-system constraints. Patients tended to foreground structural barriers, whereas providers placed more emphasis on knowledge and forgetting advice. Continued counselling, reliable medicines, and peer support emerged as priorities, but these are interview-derived design directions rather than tested interventions.

Thai researchersTemesgen Anjulo Ageru · Cua Ngoc Le · Apichai Wattanapisit · Charuai Suwanbamrung
International Journal of Qualitative Studies on Health and Well-beingRead analysis →
Forest Policy and Bioeconomy92IMPACT SIGNAL
Evidence of global relevance

Perspectives on the forest bioeconomy: insights of stakeholders from cases in Central Europe and the Mekong region

This comparative study examines how 336 purposively recruited respondents in Czechia, Slovakia, Thailand, Laos and Vietnam understand and assess the forest bioeconomy. Respondents generally reported stronger familiarity with sustainable forest management and the circular economy than with the bioeconomy itself. Perceptions also varied across country cases, particularly within the Mekong region. A binary logistic regression identified associations between high perceived implementation and country, age, education, understanding of policy aims, support for implementation and positive assessments of forest-industry implementation. These findings describe perceptions within the recruited sample rather than national populations, and the reported associations should not be interpreted as causal effects.

Thai researchersNopparat Kaakkurivaara · Alice Sharp · Prasit Wangpakapattanawong
One Health and Zoonotic-Disease Prevention92IMPACT SIGNAL
Formative evidence for One Health intervention design

Zoonotic Risk in Rural Nan Is Not Just Behavioural: Water Scarcity, Forest Change, and Food Systems Connect Five Interfaces

Researchers examined everyday practices and conditions that could enable cross-species transmission in four rural villages in Nan Province, organising findings into five interfaces: human–animal, human–environment, human-human, animal–animal, and animal–environment. The picture is not simply one of deficient knowledge. Animal contact, butchering and food preparation, water scarcity and contamination, waste, forest change, intensified agriculture, mixed-species proximity, and multilingual communication operate as a system. Community leaders and village health volunteers were viewed as trusted messengers. The study therefore recommends education that combines knowledge, skills, practical tools, and recognition of structural limits, but it neither completed nor evaluated the final intervention.

Thai researchersMonchai Phongsiri · Simaphon Tomklang · Theerayuth Labooth · Thanapat Chaibut · Pongsakon Jaruton · Kotthamon Chanprathad · Sarutaya Suphawatthanaphan · Hans Overgaard · Patcharin Lapanun
Circular Bioeconomy and Seafood Technology92IMPACT SIGNAL
Comprehensive narrative-review evidence

Crustacean By-Products Hold High-Value Compounds, but ‘Green’ Extraction Still Lacks LCA and Industrial Proof

This review compares conventional acid–alkali and solvent extraction with supercritical fluids, enzymatic hydrolysis, pulsed electric fields, ultrasound, cold plasma, microwave, high-pressure processing, and deep eutectic solvents for recovering bioactives from crustacean by-products. No technology is universally optimal: conventional methods retain advantages in simplicity and maturity, while emerging methods may reduce chemicals or better preserve product quality but face equipment, cost, energy, reproducibility, and pilot-scale constraints. The paper is therefore a map of options and evidence gaps, not proof that one technology is the ‘most sustainable.’

Thai researchersAkanksha R. Gautam · Soottawat Benjakul · Rattikarn Boonchoosri · Nilesh Nirmal · Avtar Singh
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
73IMPACT SIGNAL
Clinical Medicine

Clonostachys kasetsartana sp. nov., a novel epiphytic fungus isolated from the mangrove leaves in Thailand

INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Thailand-affiliated authors
Ananya Sahathippayakul · Vassana Supapongsri · Nattakorn Kuncharoen · Nakarin Suwannarach · Piyangkun Lueangjaroenkit
Institutions
Kasetsart University · Chiang Mai University
73IMPACT SIGNAL
Clinical Medicine

Comparative Analytical Performance and Clinical Agreement of Chemiluminescence Microparticle Immunoassay and Electrochemiluminescence Immunoassay for CA19-9: A Diagnostic Accuracy Study

Diagnostics

Thailand-affiliated authors
Jongkonnee Wongpiyabovorn · Nasornthan Yutthakasaemsan · Sunida Vandelaer
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Citywide re-evaluation of the Bangkok air quality health index: classification performance, nonlinear same-day respiratory associations, and implications for precautionary health communication

BMC Public Health

Thailand-affiliated authors
Suwimon Kanchanasuta · Narongpon Dumavibhat · Nakarin Sansanayudh · Chathaya Wongrathanandha · Thammasin Ingviya · Piti Chalongviriyalert · Dittapol Muntham · Sarawuth Limprasert
Institutions
Mahidol University · Siriraj Hospital · Armed Forces Research Institute of Medical Science · Ramathibodi Hospital · Prince of Songkla University · Bangkok Metropolitan Administration · Charoenkrung Pracharak Hospital · Rajamangala University of Technology Suvarnabhumi · Phramongkutklao Hospital
73IMPACT SIGNAL
Clinical Medicine

Knowledge, attitudes, and practices (KAP) of caregivers regarding PM2.5 exposure among children in Northern Thailand: a cross-sectional study on the knowledge–practice gap

The Journal of Climate Change and Health

Thailand-affiliated authors
Suparat Phuanukoonnon · Pyae Linn Aung · Wissanupong Kliengchuay · Sarima Niampardit · Nuttapohn Kiangkoo · Rachaneekorn Mingkhwan · Paweena Aendo · Sawaeng Kawichai · Kotchakorn Khammoon · Tippawan Prapamontol · Nguyen Thi Kim Oanh · Walaiporn Phonphan · Kraichat Tantrakarnapa
Institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit · Chiang Mai University · Asian Institute of Technology · Suan Sunandha Rajabhat University
73IMPACT SIGNAL
Clinical Medicine

Association between Warfarin Exposure and Intracranial Arterial Calcification in 645 Patients without Trauma

Asian Journal of Neurosurgery

Thailand-affiliated authors
Chanya Chotchungchutchaval · Chaithud Kerdtubtim · Bunpot Sitthinamsuwan · Chanon Ngamsombat · Chottiwat Tansirisithikul · Sarun Nunta-aree
Institutions
Siriraj Hospital · Mahidol University
73IMPACT SIGNAL
Global Public Health

Transcriptome profiling analysis of heat-adapted and heat-sensitive breeder hen jejunal mucosal tissues in response to acute heat stress

BMC Veterinary Research

Thailand-affiliated authors
Yongcai Zhu · Satoshi Kubota · Phocharapon Pasri · Sitthipong Rakngam · Sutisa Khempaka
Institutions
Suranaree University of Technology
73IMPACT SIGNAL
Clinical Medicine

Cannabinoid therapeutics in the 21st century: from molecular mechanisms to equitable clinical integration

Exploration of Drug Science

Thailand-affiliated authors
Mohamed Mustaf Ahmed
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Impact of Copper and Melezitose Supplementation on Adalimumab Production and N-linked Glycosylation in Chinese Hamster Ovary Cell Culture

Chiang Mai Journal of Science

Thailand-affiliated authors
Montarop Yamabhai
Institutions
Suranaree University of Technology
73IMPACT SIGNAL
Clinical Medicine

Complete metabolic response in stage IV Merkel cell carcinoma after combined avelumab and radiotherapy: a case report suggestive of an abscopal effect

Frontiers in Oncology

Thailand-affiliated authors
Mariana Cecilia Macías-Flores
Institutions
Surin Hospital
73IMPACT SIGNAL
Global Public Health

Prevalence, multi-drug resistance, and public health risks of Salmonella Enterica in poultry farms and markets of Nekemte, Ethiopia: a cross-sectional study

Scientific Reports

Thailand-affiliated authors
Hunde Weyuma Balcha
Institutions
Department of Livestock Development
73IMPACT SIGNAL
Multidisciplinary

Acute and Chronic Toxicity Tests and Assessment of In Vitro and In Vivo Anti-Allergic Effects of Prabchompoothaweep Remedy

International Journal of Molecular Sciences

Thailand-affiliated authors
Sunita Makchuchit · Pattarapol Pusiripinyo · Areeratna Jai-uea · Pranporn Kuropakornpong · Seewaboon Sireeratawong · Parirat Khonsung · Arunporn Itharat
Institutions
Thammasat University · Chiang Mai University
73IMPACT SIGNAL
Multidisciplinary

Corn Stover-DerivedLewis Acid Carbon Catalyst forEfficient Hantzsch Synthesis of 1,4-Dihydropyridines

ACS Omega

Thailand-affiliated authors
Kanyaphat Torboon · Chatthai Kaewtong · Supinya Nijpanich · Nopbhasinthu Patdhanagul · Prasong Srihanam · Andrew J. Hunt · Pakin Noppawan
Institutions
Mahasarakham University · Synchrotron Light Research Institute · Kasetsart University · Khon Kaen University
73IMPACT SIGNAL
Clinical Medicine

Prediction of 1500 m freestyle performance in age-group swimmers based on synthetic data and symbolic regression

Journal of Sports Sciences

Thailand-affiliated authors
Phornpot Chainok · Radomyos Matjiur
Institutions
Burapha University
73IMPACT SIGNAL
Environmental Engineering

Heavy Metal Contamination and Water Quality Deterioration Along the River–Estuary Continuum of the Cisadane River, Indonesia

Environmental Forensics

Thailand-affiliated authors
Triyoni Purbonegoro
Institutions
Department of Marine and Coastal Resources
73IMPACT SIGNAL
Energy and Materials

Extemporaneous dual-drug-loaded contact lenses containing ceftazidime and cefazolin for perforated bacterial keratitis

Scientific Reports

Thailand-affiliated authors
Pratthana Chomchalao · Aphiradee Boonkham · Waree Tiyaboonchai · Rossukon Khotcharrat
Institutions
Ubon Ratchathani University · Rambhai Barni Rajabhat University · Naresuan University
73IMPACT SIGNAL
Energy and Materials

Growth of Single and Bimetallic Nickel and Cobalt Compounds for High Performance Supercapacitors via Fluoride-Based Structure-Directing Regulation

ACS Applied Energy Materials

Thailand-affiliated authors
Chutima Kongvarhodom
Institutions
King Mongkut's University of Technology Thonburi
73IMPACT SIGNAL
Environmental Engineering

Trimeric autotransporter adhesins driving chain-like adhesion diversify surface colonization strategies in Shiga toxin-producing Escherichia coli

Nature Communications

Thailand-affiliated authors
Yukihiro Akeda
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

A Plasmodium vivax Case Identified Solely via the Use of Next-Generation Sequencing

American Journal of Tropical Medicine and Hygiene

Thailand-affiliated authors
Christen Rune Stensvold
Institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
73IMPACT SIGNAL
Global Public Health

Effect of Brief Pharmacist Counseling on Knowledge, Perception, Adherence, and Hemoglobin in Second-Trimester Pregnancy at a Community Health Center

INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal)

Thailand-affiliated authors
Win Win Khaing Shwe
Institutions
Mahidol University
73IMPACT SIGNAL
Clinical Medicine

From Glycocodeto Precision Oncology: TherapeuticStrategies Targeting Aberrant O -GalNAc Glycosylationin Cancer

Chemical Reviews

Thailand-affiliated authors
Thapakorn Jaroentomeechai
Institutions
Mahidol University
73IMPACT SIGNAL
Clinical Medicine

Effect of Nine-Square Counting Dance on Physical and Cognitive Function in Older Adults with Mild Cognitive Impairment: A Randomized Controlled Trial

Asian Health, Science and Technology Reports

Thailand-affiliated authors
Donlaya Promkeaw · Chartnakrop Laksanakunlabutr · Natthaporn Muangsuk · Sithanan Promsri · Ampha Pumpho · Titi Phanjaroen · Theerasak BOONWANG
Institutions
Mae Fah Luang University
73IMPACT SIGNAL
Energy and Materials

Electrolyte Development for LFP//Graphite Cells: Attempts to stop Fe dissolution from LFP

Journal of The Electrochemical Society

Thailand-affiliated authors
Thitiphum Sangsanit · Montree Sawangphruk
Institutions
Vidyasirimedhi Institute of Science and Technology
73IMPACT SIGNAL
Digital Health

Smart Geospatial Analytics for Maladaptation Hotspot Detection: Integrating Trajectory Classification, Random Forest, and SHAP

Sensors

Thailand-affiliated authors
Nutchanat Buasri · Patiwat Littidej · Benjamabhorn Pumhirunroj · Kaveepoj Banluewong
Institutions
Mahasarakham University · Sakon Nakhon Rajabhat University
73IMPACT SIGNAL
Digital Health

Lightweight Deep Learning Models for Six-Stage Maturity Classification of Arabica Coffee Cherries Using RGB Imaging

Smart Agricultural Technology

Thailand-affiliated authors
Phuangphet Hemrattrakun · Phonkrit Maniwara · Nuttapon Khongdee · Krit Khetanun · Thanchanok Yosen · Butian Wang · Chawakorn Sri-Ngernyuang
Institutions
Chiang Mai University · Maejo University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link