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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
Public Health74IMPACT SIGNAL
Evidence of global relevance

Severe Pregnancy-Associated Acute Kidney Injury and Maternal Vulnerability

Electronic records covering 4,094,111 US pregnancies showed severe pregnancy-associated acute kidney injury rising from 9.0 to 27.6 per 10,000 pregnancies between 2012-2013 and the COVID-19 era. Pre-existing cardiometabolic vulnerability was associated with risk, but observational data cannot separate infection, access, testing, and secular trends.

Thai researchersNattachai Srisawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Integrative hematological and transcriptomic analysis reveals monocyte alterations and molecular signatures of inflammatory-coagulation crosstalk in long COVID

A comparison of 21 people with long COVID and 24 asymptomatic controls found lower white-cell, monocyte, and platelet counts and longer APTT. Integrated with a separate public transcriptomic dataset, the findings support a proposed inflammation-coagulation model, but the small and non-identical datasets cannot establish mechanism.

Thai researchersParin Kamseng · Namngern Chantaramanee · Rittikorn Sompan · Sarayot Rareongjai
Public Health74IMPACT SIGNAL
Evidence of global relevance

Toxicological Assessment of Oligofructans Derived from Raw Sugar Fermentation by Bacillus subtilis TISTR 001 and Their Modulatory Effects on Rat Gut Microbiota

Thai researchers evaluated oligofructans produced from raw sugar using Bacillus subtilis TISTR 001. Rats showed no treatment-related mortality or toxicity at doses up to 2,000 mg/kg/day for 90 days, alongside reported shifts in gut microbial taxa. These are preclinical animal findings and do not establish human safety or benefit.

Thai researchersSirinya Taya · Boontiwa Ninchan · Sonthaya Umsumarng · Jutamat Klinsoda · Rawiwan Wongpoomchai · Charatda Punvittayagul
Environment and Engineering74IMPACT SIGNAL
Evidence of global relevance

A Multi-Frequency SAR Framework for Methane Emission Estimation in Thai Rice Paddies

A GISTDA-led framework combines Sentinel-1 and ALOS-2 radar with IPCC accounting to detect crop timing, classify water regimes, and estimate methane from irrigated rice in Thailand's central plain. Mean absolute error was 18.5 kg CH4/ha, but structural uncertainty in the IPCC Tier 1 emission factor exceeded all algorithmic errors combined.

Thai researchersNuntikorn Kitratporn · Kanjana Koedkurang · Panu Nueangjamnong · Kittiphop Simachokchai · Chompunut Chayawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Predictors of Early Recurrence and Survival Outcomes Following Curative Resection for Colorectal Liver Metastases and the Role of Salvage Surgery: A Retrospective Cohort Study

In a retrospective cohort of 109 patients undergoing liver resection for colorectal liver metastases, high tumor burden, major intraoperative blood loss, T3/T4 primary disease, and RAS mutation were associated with early recurrence. Selected patients undergoing salvage re-hepatectomy had favorable long-term survival, but small subgroups and strong selection bias prevent causal conclusions.

Thai researchersPipit Burasakarn · Nisanat Thongkua · Vachiraluck Chalokool · Anuparp Thienhiran · Sermsak Hongjinda · Pusit Fuengfoo
Mental Health74IMPACT SIGNAL
Evidence of global relevance

The Study of Efficacy and Safety of a Modified Chaihu Shugan San Formula in the Treatment of Insomnia Associated with Stress: A Pilot Clinical Evaluation

A 30-participant pre-post pilot reported lower sleep-quality and stress scores after four weeks of twice-daily modified Chaihu Shugan San, without clear liver or renal safety signals. Without randomization, a control group, or placebo, the study cannot separate the formula's effect from placebo, attention, or change over time.

Thai researchersPorwarut Srihara · Cao ZuoJun · Somratchanee Srifar · Mattanapat Phraecharoen
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Benefits of three consecutive sputum inductions using nebulized racemic salbutamol versus hypertonic saline in smear-negative or sputum-scarce pulmonary tuberculosis patients: a prospective randomized, double-blind study

In a randomized double-blind trial of 345 adults with suspected smear-negative or sputum-scarce pulmonary tuberculosis, three consecutive daily inductions with nebulized racemic salbutamol produced a higher combined smear-or-culture yield and fewer adverse events than 3% hypertonic saline. The single-center study evaluates specimen collection for diagnosis, not tuberculosis treatment outcomes.

Thai researchersWarangkana Keeratichananont · Suriya Keeratichananont · Natthaphon Ubonsutvanich · Jirachaya Chaisurote
Thai Fruit and Diabetic Retinal Mechanisms74IMPACT SIGNAL
Evidence of global relevance

ANTIOXIDANT AND ANTI-APOPTOTIC ACTIVITIES OF MAKIANG FRUIT EXTRACT IN ARPE-19 CELLS EXPOSED TO GLUCOSE-INDUCED CELLULAR DAMAGE

A 95% ethanol makiang-fruit extract showed antioxidant activity and, when co-administered in 30 mM glucose-exposed ARPE-19 cells, the highest 200 microgram/mL dose increased viability by 15.4%, reduced ROS by 37.8%, and lowered caspase-9 and -3 activities.

Thai researchersNuntaporn Chanpurk · Kemika Praengam · Angkalsiri Deeaum · Pasitta Panritdum · Monruedee Sukprasansap · Chawanphat Muangnoi
Green-Tea Compounds and Diabetic Kidney Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Epigallocatechin-3-gallate, l-theanine and theophylline abolish high-glucose-induced renal cell senescence and subsequent epithelial-mesenchymal transition and fibroblast activation via SIRT1/PGC-1α axis: Implications for diabetic kidney disease

High glucose induced senescence in proximal tubular cells, whose SASP-conditioned medium then triggered epithelial-mesenchymal transition in distal tubular cells and fibroblast activation. EGCG, L-theanine, and theophylline suppressed these effects while restoring SIRT1/PGC-1alpha signaling.

Thai researchersRattiyaporn Kanlaya · Sunisa Yoodee · Kanokwan Nonthawong · Chonicha Subkod · Supanan Nanthawuttiphan · Visith Thongboonkerd
Curcumin and Breast-Tumor Immunity74IMPACT SIGNAL
Evidence of global relevance

Curcumin Attenuates Breast Cancer Cell-induced Inflammasome Activation via the NOD-like receptor protein 3/Caspase-1/Interleukin-1β Axis

Breast-cancer-cell conditioned medium drove THP-1-derived macrophages toward a pro-inflammatory tumor-associated phenotype with higher IL-1beta, NLRP3, and caspase-1. Curcumin pretreatment reduced IL-1beta secretion, NLRP3 protein, and IL1B/CASP1 transcripts.

Thai researchersKhwandow Kunchana · Wattanased Jarisarapurin · Suvara K. Wattanapitayakul
Encephalitis Viruses and Cell-Death Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Inhibition of calpain-mediated BAX cleavage attenuates Japanese encephalitis virus-induced apoptosis in SH-SY5Y neuroblastoma cells

In SH-SY5Y cells, Japanese encephalitis virus activated calpain to cleave BAX into p18 BAX, which moved to mitochondria and triggered cytochrome c, caspase-3, PARP cleavage, and apoptosis. The calpain inhibitor calpeptin attenuated these signals and improved cell viability.

Thai researchersKuntida Kitidee · Arisara Samutpong · Nattaporn Pakpian · Montri Yasawong · Prapimpun Wongchitrat
Occupational Lung Health and AI Screening74IMPACT SIGNAL
Evidence of global relevance

Artificial neural network modelling using complete blood count for the early detection of black lung disease among Indonesian coal miner: A retrospective longitudinal study

Annual health data from 807 Indonesian coal miners followed from 2013-2021 showed 13.9% cumulative black-lung incidence. A complete-blood-count neural network and Cox model both identified eosinophils and monocytes as influential predictors.

Thai researchersKurnia Ardiansyah Akbar · Kraiwuth Kallawicha · Pallop Siewchaisakul
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
73IMPACT SIGNAL
Environmental Engineering

From Aquatic Pollution to Drinking-Water Exposure: Analytical Challenges in Detecting Nanoplastics in Drinking Water—A PRISMA-Guided Review

Molecules

Thailand-affiliated authors
José Roberto Vega‐Baudrit · Felipe Orozco
Institutions
National Nanotechnology Center
73IMPACT SIGNAL
Environmental Engineering

Life Cycle Assessment of Conventional and Organic Rice Production Under Alternative Irrigation Management in Thailand

Agriculture

Thailand-affiliated authors
Sittinun Tawkaew · Parinya Khongprom · Unchalee Suwanmanee
Institutions
Srinakharinwirot University · Prince of Songkla University
73IMPACT SIGNAL
Clinical Medicine

Development of a prognostic prediction model for tumor recurrence or progression in gastrointestinal stromal tumors: integrating inflammatory blood indices with 5 mm 2 versus 50 high-power field mitotic counts

Journal of Pathology and Translational Medicine

Thailand-affiliated authors
Waratchaya Tirasarnvong · Thammasin Ingviya · Paramee Thongsuksai
Institutions
Prince of Songkla University
73IMPACT SIGNAL
Environmental Engineering

Crossbred boars achieve greater semen-collection training success than purebreds, independent of environmental enrichment

Frontiers in Animal Science

Thailand-affiliated authors
Ariane Cristina de Castro · Robson Mateus Freitas Silveira · Daniela Silveria de Lana · Iran José Oliveira Silva
Institutions
Department of Livestock Development
73IMPACT SIGNAL
Clinical Medicine

BifunctionalLaser-Induced Graphene Platforms forIntegrated Electrochemical Sensing and Matrix-Free LDI-MS Quantitationof Sarcosine

Analytical Chemistry

Thailand-affiliated authors
Wimala Karintrithip · Pumidech Puthongkham · Pranee Rattanawaleedirojn · Narong Praphairaksit · Nadnudda Rodthongkum
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Long-term outcomes of asymptomatic microscopic haematuria in an outpatient department

Journal of Health Research

Thailand-affiliated authors
Chidjan Prommajan · Tharntip Sangsuwan · Silom Jamulitrat
Institutions
Prince of Songkla University
73IMPACT SIGNAL
Clinical Medicine

Association between anthropometric measures and abdominal wall thickness in patients with obesity: A cross-sectional CT study

PLoS ONE

Thailand-affiliated authors
Prasit Mahawongkajit · Porrawat Rodsa · Saritphat Orrapin
Institutions
Thammasat University · Thammasat University Hospital
73IMPACT SIGNAL
Clinical Medicine

Navigation-Assisted Unilateral Biportal Endoscopic Decompression of Far-Out Compression in Bertolotti Syndrome: A Technical Note

Journal of Minimally Invasive Spine Surgery and Technique

Thailand-affiliated authors
Warayos Trathitephun · Jackapol Kamolpak · Rathapoom Suwanaratana · Siravich Suvithayasiri
Institutions
Chulabhorn Hospital
73IMPACT SIGNAL
Clinical Medicine

Overcoming the Challenge of Controlled Total Facetectomy in Uniportal Endoscopic Transforaminal Interbody Fusion: A Direct-Visualization Crown-Reaming Technique

Journal of Minimally Invasive Spine Surgery and Technique

Thailand-affiliated authors
Warayos Trathitephun · Jackapol Kamolpak · Rathapoom Suwanaratana · Siravich Suvithayasiri
Institutions
Chonburi Hospital · Chulabhorn Hospital
73IMPACT SIGNAL
Clinical Medicine

A multicenter study of crisaborole use in pediatric patients with atopic dermatitis in real-world setting in Thailand.

PubMed

Thailand-affiliated authors
Susheera Chatproedprai · Nootchanard Rujimethapass · Patawee Na Bangxang · Siriwan Wananukul · Wanida Limpongsanurak · Wanee Wisuthsarewong · Srisupalak Singalavanija · Karaked Chantawarangul · Kantima Kanchanapoomi · Therdpong Tempark · Chonnakarn Sukneewat · Rattanavalai Nitiyarom
Institutions
Chulalongkorn University · Queen Sirikit National Institute of Child Health · Siriraj Hospital · Mahidol University
73IMPACT SIGNAL
Clinical Medicine

In Situ Fabrication of Bacterial Cellulose–Polyhydroxyalkanoate Composite Membranes from Coconut Water: Mechanical Performance and Life Cycle Assessment

Gels

Thailand-affiliated authors
Panuvit Rienpradub · Suphuttra Boonmak · Anuchan Panaksri · Sani Boonyagul · Patnarin Worajittiphon · Woradej Pichaiaukrit · Ghit Laungsopapun · Korawan Sringarm · Pornchai Rachtanapun · Kittisak Jantanasakulwong · Nuttapol Tanadchangsaeng
Institutions
Rangsit University · Chiang Mai University · Thailand Institute of Scientific and Technological Research
73IMPACT SIGNAL
Clinical Medicine

Breaking host barriers: detection of Cytauxzoon banethi in a non-felid feliform, the striped hyena (Hyaena hyaena)

International Journal for Parasitology Parasites and Wildlife

Thailand-affiliated authors
Domenico Otranto
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Energy and Materials

Heat stress-induced metabolic responses enhance antioxidant capacity, phenolic and flavonoid accumulation in Bacopa monnieri callus cultures

Folia Horticulturae

Thailand-affiliated authors
Prathan Luecha · Narisa Kunpratum · Attachai Trunjaruen · Pitakpong Maneerattanarungroj · Worasitikulya Taratima
Institutions
Khon Kaen University · Naresuan University · Burapha University
73IMPACT SIGNAL
Clinical Medicine

Epidemiology, transmission, vector and factors analysis of chikungunya outbreak in 2025, Quanzhou City of China

Frontiers in Public Health

Thailand-affiliated authors
Roger Frutos
Institutions
Ramathibodi Hospital
73IMPACT SIGNAL
Clinical Medicine

Review Article: Accelerating Coeliac Disease Clinical Trials—Beyond Celiac Meeting With Industry, Academics, Patients and the FDA

Alimentary Pharmacology & Therapeutics

Thailand-affiliated authors
Kristie Grebe
Institutions
Nation University
73IMPACT SIGNAL
Multidisciplinary

Integrative Evidence Reveals Two New Species in the Millipede Genus Coxobolellus Pimvichai, Enghoff, Panha & Backeljau, 2020 and Reassigns Benoitolus siamensis (Attems, 1936) to the Genus Pseudospirobolellus Carl, 1912 (Diplopoda: Spirobolida: Pseudospirobolellidae)

Animals

Thailand-affiliated authors
Piyatida Pimvichai
Institutions
Mahasarakham University
73IMPACT SIGNAL
Clinical Medicine

Dual bispecific protein engager–armed T cells targeting BCMA and B7-H3 overcome antigen heterogeneity in multiple myeloma

Biomedicine & Pharmacotherapy

Thailand-affiliated authors
Thanida Chanpong · Nunghathai Sawasdee · Kamonlapat Supimon · Thanich Sangsuwannukul · Thaweesak Chieochansin · Pa‐thai Yenchitsomanus · Mutita Junking
Institutions
Siriraj Hospital
73IMPACT SIGNAL
Clinical Medicine

Evaluation of acoustic pulse and cold laser therapies for the treatment of dairy cows with subclinical mastitis under organic management conditions

Frontiers in Veterinary Science

Thailand-affiliated authors
Guy Jodarski
Institutions
Ministry of Agriculture and Cooperatives
73IMPACT SIGNAL
Multidisciplinary

Just how far off target are we? Measuring unmet pre-exposure prophylaxis need among men who have sex with men and transgender women in Asia-Pacific

Sexual Health

Thailand-affiliated authors
Nittaya Phanuphak
Institutions
Bangkok University
73IMPACT SIGNAL
Digital Health

An analogical argumentation framework for argumentative local explainers

Argument & Computation

Thailand-affiliated authors
Nguyen Duy Hung · Thanaruk Theeramunkong
Institutions
Thammasat University · The Royal College Of Anesthesiologists Of Thailand
73IMPACT SIGNAL
Clinical Medicine

Alpha-Mangostin in Acute Kidney Injury: Molecular Mechanisms, Regulated Cell Death, and Translational Opportunities

Antioxidants

Thailand-affiliated authors
Atthaphong Phongphithakchai · Nawanwat C. Pattaranggoon · Kraiyasak Wongna · Ratana Netphakdee · Aman Tedasen · Chutima Jansakun · Wiyada Kwanhian Klangbud · Jongkonnee Thanasai · Moragot Chatatikun
Institutions
Prince of Songkla University · Walailak University · Nakhon Phanom University · Mahasarakham University
73IMPACT SIGNAL
Global Public Health

Biotechnological Advances of Lactic Acid Bacteria in Maghrebian Countries: An Updated Review

Biotechnology and Applied Biochemistry

Thailand-affiliated authors
Pankaj Koirala · Nilesh Prakash Nirmal
Institutions
Mahidol University
73IMPACT SIGNAL
Energy and Materials

Fe-doped BiVO4/g-C3N4 heterojunction for efficient tetracycline degradation under low-intensity UV irradiation

Scientific Reports

Thailand-affiliated authors
Supakorn Boonyuen
Institutions
Thammasat University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link