Phetchabun Screens 97.3% for HCV; 96.4% of SVR12-Evaluable Patients Are Cured, but Transmission Elimination Is Unproven
Phetchabun’s micro-elimination programme linked fingerstick anti-HCV testing, HCV-RNA confirmation, and 12-week sofosbuvir/velpatasvir treatment through primary-care and district-hospital services across all 11 districts under universal health coverage. From 2020 to April 2026, 389,547 of 400,567 targeted people were screened (97.25%); 14,845 of 18,340 anti-HCV-reactive participants received RNA confirmation (80.94%), identifying 10,996 active infections. Of 8,961 treatment-eligible patients, 8,842 received therapy (98.67%); among 6,719 evaluated at SVR12, 6,474 were cured (96.35%). The programme demonstrates province-scale test-to-treat feasibility, but not yet the incidence or mortality reductions required for elimination.
Wijitra Phaengkha · Pornjarim Nilyanimit · Nungruthai Suntronwong · Jiratchaya Puenpa · Duong Hoang Huy Le · Saranya Ngamnimit · Pattama Janpathip · Lapasrada Kamput · Kawin Thongnoi · Wanalee Toomta · Phatcha Wohanklong · Jarunlak Saokeaw · Niphapornt Thammajit · Suwannee Rerngleum · Ananyalak Yoisara · Nitiya Srisuk · Jidapa Suwannachat · Anchalee Karagate · Rujipat Wasitthankasem · Yong PoovorawanNam Nao Hospital, Phetchabun · Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University · Phetchabun Provincial Public Health Office · Phetchabun Hospital · Buengsamphan Hospital · Lomsak Hospital · Chondaen Hospital · Si Thep Hospital · Wang Pong Hospital · Wichianburi Hospital · Lomkao Crown Prince Hospital · Nongphai Hospital · Khao Kho Hospital · National Center for Genetic Engineering and Biotechnology, NSTDA · The Royal Society of Thailand
Paired samples from treatment-naïve gastric-cancer patients and controls showed substantially higher richness and diversity with mucosal brushing than biopsy. Brushing detected lower diversity and altered composition in cancer, whereas biopsy did not. Sampling method shapes microbiome signals, but causation and diagnostic utility are unproven.
Gizzard lesions in Thai chickens contained intranuclear inclusions, in-situ hybridization signal and PCR-confirmed fowl adenovirus. Hexon and fibre sequencing identified FAdV-8a strain FAdV8a_NPT_KU001_25, closer to a gizzard-tropic than an inclusion-body-hepatitis strain. Association is supported, but causation remains unproven.
A two-clinic Chiang Mai study of 150 MSM and transgender women found clinically significant depression in 5.3% of PrEP users and 13.3% of non-users. Mean depression was lower among PrEP users, while suicidal ideation occurred in 5.3% with no group difference.
An exploratory case-control study of 37 Thai adults with confirmed beta-lactam hypersensitivity identified HLA-DQA1*01:04 and HLA-DQA1*05:05 candidate signals after Bonferroni correction, with the latter stronger for immediate reactions. Small size, population controls and sensitivity-instability mean the findings are not ready for screening or drug avoidance.
Twenty male esports players were randomised to cup stacking three days weekly for four weeks or usual training. Post-intervention salivary alpha-amylase fell within the experimental group and differed significantly from controls.
Giant freshwater prawns received control diets or 10% and 20% fishmeal replacement with L. plantarum TISTR1284-fermented Leucaena for two weeks. Fermented diets increased immune markers and reduced post-A. hydrophila mortality by 26.14%, with normal intestinal morphology.
The systematic review identified 17 reports representing 15 randomised trials with 6,256 participants; 2,216 contributed to overweight subgroup analyses. The meta-analysis included 12 studies and 1,728 pregnant women with overweight. Interventions combined diet and physical activity, often with goal setting, self-monitoring and digital or remote follow-up.
A seven-country prospective cohort of 1,703 adults with HIV found Mycobacterium tuberculosis bloodstream infection predominantly among inpatients and associated it with higher 30-day mortality.
An evaluation of 1,838 stored sera from seven countries found that a second-generation Hcp1 antibody test had sensitivity ranging from 48% to 92%, with specificity varying by country and comparison group.
Thai researchersHasyanee Binmaeil · Thanakon Bunsong · Mary N. Burtnick · Paul J. Brett · Narisara Chantratita
Analysis of Thai national claims from 2015–2023 identified 60,916 paediatric hepatobiliary admissions. Admission rates were broadly stable and in-hospital mortality declined, while hepatic failure remained a high-risk condition.
An international expert statement spanning 22 countries reviews links among food systems, cardiometabolic health and the Sustainable Development Goals. It advocates plant-forward traditional diets rich in whole grains, legumes, vegetables, fruit, nuts and spices, with meat used sparingly.
The multicentre survey analysed 604 patients from 25 Thai hospitals between December 2023 and March 2024. SSRIs accounted for 70.2% of prescriptions, followed by TCAs at 13.9% and trazodone at 12.7%. The most common diagnoses were depressive disorders (55.0%), substance use disorders (15.2%) and psychotic disorders (13.7%). Clinicians cited limited availability (21.9%), reimbursement arrangements (36.3%) and patient finances (33.9%) as prescribing constraints.
Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.
3,510records
3,510 records
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Clinical Medicine
Clinical Characteristics, Antimicrobial Susceptibility, Treatment, and Outcomes of Achromobacter Bacteremia: A 20-Year Retrospective Cohort Study
Khon Kaen University · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
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Clinical Medicine
Soluble C-type lectin LvLectin1 mediates recognition and agglutination of Ecytonucleospora hepatopenaei spores in Pacific white shrimp Litopenaeus vannamei
Navamindradhiraj University · Vajira Hospital · Srinakharinwirot University · Ministry of Public Health
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Clinical Medicine
Effects of Ramadan Fasting on Intradialytic Hypoglycemia and Clinical Outcomes in Patients with Diabetes on Maintenance Hemodialysis: A Multicenter Prospective Cohort Study in Southern Thailand
Gelatin Hydrolysate from Bigeye Snapper (Priacanthus tayenus) Skin Attenuates the Progression of Diabetic Nephropathy in Rats by Modulating Oxidative Stress, Inflammatory Responses, and Endoplasmic Reticulum Stress Signaling Pathways
Chiang Mai University · Kasetsart University · University of Phayao
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Energy and Materials
Unlocking High-Valent Chalcogen Redox with Halide-Rich Electrolytes for High-Energy Lithium Batteries
Nature Communications
Thailand-affiliated authors
Jiaqian Qin
Institutions
Chulalongkorn University
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Clinical Medicine
Prediction model for survival outcome in patients with acute myeloid leukemia: a multicenter prospective cohort study from Thai Acute Leukemia Working Group
Prince of Songkla University · Chiang Mai University · Siriraj Hospital · Chulalongkorn University · King Chulalongkorn Memorial Hospital · Thammasat University · Phramongkutklao Hospital · Ramathibodi Hospital · Rajavithi Hospital · Khon Kaen University
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Clinical Medicine
Immune response and durability of human papillomavirus antibodies in vaccinated adolescents after hematopoietic stem cell transplantation: a pilot study
Culturable mycota from Karst caves in Yunnan Province, China
IMA Fungus
Thailand-affiliated authors
Xiang-Fu Liu · K. W. Thilini Chethana · Lu Li · Kevin D. Hyde · Wenhua Lu · Rui-Fang Xu · Xue-Mei Chen · Xian Zhang · Xing-Juan Xiao · Tian‐Ye Du · Nakarin Suwannarach · Jaturong Kumla
Institutions
Mae Fah Luang University · Chiang Mai University
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Clinical Medicine
Association of Vitamin D Intake, VDR Levels, and Relevant Gene Polymorphisms in Early-Stage Thai Colorectal Cancer Patients Following Vitamin D3 Supplementation
