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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
Geospatial Agriculture and Environment89IMPACT SIGNAL
Regional model-validation evidence

GEDI–Sentinel Model Maps Northeast Thai Rubber at 82.63% Accuracy but Struggles With Young Plantations

This study mapped 2024 rubber distribution and age structure across Northeast Thailand using Random Forest in Google Earth Engine, combining Sentinel-1, Sentinel-2, vegetation indices, and a GEDI-trained canopy-height model. Three-class rubber mapping reached 82.63% overall accuracy and about 0.84 F1; three-group age classification reached 83.39%. Plantations older than seven years dominated and were classified more reliably than young stands. The output is a regional monitoring baseline, not an error-free parcel-level decision map.

Thai researchersSavittri Ratanopad Suwanlee · Muhammad Hanif · Surasak Keawsomsee · Kemin Kasa · Narissara Nuthammachot · Sarawut Ninsawat · Jantima Polpinij · Jaturong Som-Ard
Medical Education and Serious-Illness Care89IMPACT SIGNAL
Longitudinal training evidence

Advance-Care-Planning Training Raised Residents’ Knowledge From 7.74 to 8.65, but Had No Control Group

This mixed-methods evaluation tested an Advance Care Planning programme combining role-play, personal-value reflection, and two Circle of Learning sessions with an entire cohort of 50 first-year internal-medicine residents. Longitudinal analysis used 34 complete cases through 15 months, and 10 residents were interviewed. Knowledge rose from 7.74 to 8.65 out of 9, alongside several attitude and confidence improvements. Interviewees said role-play bridged theory and practice but identified a need for ongoing workplace support. The evidence concerns learner readiness, not observed conversation quality or patient outcomes.

Thai researchersThagoon Kanjanopas · Smuch Siramongkholkarn · Wanna Jarusomboon · Ekkapop Sittiwantana · Arisa Phochaisarn · Saipin Hathirat · Saran Thanapluetiwong
Public Health and Migrant Health92IMPACT SIGNAL
Evidence of global relevance

Migrant TB Patients Chose Months-Long Sanatorium Care to Pursue Cure Amid Cost, Transport, and Documentation Barriers

This multi-perspective qualitative study at the SMRU tuberculosis sanatorium in Mae Ramat, Tak Province, examined why migrants choose long residential treatment. It included 37 unique patients—33 who chose the sanatorium and four who chose community DOTS—plus five health workers. Three themes organized the findings: desire for cure, barriers to diagnosis and treatment, and community and organizational support.

Thai researchersJindaporn Wirachonphaophong · Hai Ti Ti · Nay Kaw Htoo · Kanjana Winyoorat · Cha Ba · San Soe · Suphak Nosten · Htet Ko Ko Aung · Sein Sein Thi · Francois Nosten
Public Health and Health Systems92IMPACT SIGNAL
Qualitative evidence for service design

Patients in South Ethiopia Know How to Manage Diabetes, but Drug Shortages and Costs Undercut Self-Care

This qualitative study examined diabetes self-care in three South Ethiopian hospital clinics. Its 21 participants comprised 12 adults with type 2 diabetes and nine healthcare providers. Patients described medication, diet, physical activity, foot care, and glucose monitoring as daily work negotiated against financial pressure, drug shortages, beliefs, food costs, limited support, and health-system constraints. Patients tended to foreground structural barriers, whereas providers placed more emphasis on knowledge and forgetting advice. Continued counselling, reliable medicines, and peer support emerged as priorities, but these are interview-derived design directions rather than tested interventions.

Thai researchersTemesgen Anjulo Ageru · Cua Ngoc Le · Apichai Wattanapisit · Charuai Suwanbamrung
International Journal of Qualitative Studies on Health and Well-beingRead analysis →
Forest Policy and Bioeconomy92IMPACT SIGNAL
Evidence of global relevance

Perspectives on the forest bioeconomy: insights of stakeholders from cases in Central Europe and the Mekong region

This comparative study examines how 336 purposively recruited respondents in Czechia, Slovakia, Thailand, Laos and Vietnam understand and assess the forest bioeconomy. Respondents generally reported stronger familiarity with sustainable forest management and the circular economy than with the bioeconomy itself. Perceptions also varied across country cases, particularly within the Mekong region. A binary logistic regression identified associations between high perceived implementation and country, age, education, understanding of policy aims, support for implementation and positive assessments of forest-industry implementation. These findings describe perceptions within the recruited sample rather than national populations, and the reported associations should not be interpreted as causal effects.

Thai researchersNopparat Kaakkurivaara · Alice Sharp · Prasit Wangpakapattanawong
One Health and Zoonotic-Disease Prevention92IMPACT SIGNAL
Formative evidence for One Health intervention design

Zoonotic Risk in Rural Nan Is Not Just Behavioural: Water Scarcity, Forest Change, and Food Systems Connect Five Interfaces

Researchers examined everyday practices and conditions that could enable cross-species transmission in four rural villages in Nan Province, organising findings into five interfaces: human–animal, human–environment, human-human, animal–animal, and animal–environment. The picture is not simply one of deficient knowledge. Animal contact, butchering and food preparation, water scarcity and contamination, waste, forest change, intensified agriculture, mixed-species proximity, and multilingual communication operate as a system. Community leaders and village health volunteers were viewed as trusted messengers. The study therefore recommends education that combines knowledge, skills, practical tools, and recognition of structural limits, but it neither completed nor evaluated the final intervention.

Thai researchersMonchai Phongsiri · Simaphon Tomklang · Theerayuth Labooth · Thanapat Chaibut · Pongsakon Jaruton · Kotthamon Chanprathad · Sarutaya Suphawatthanaphan · Hans Overgaard · Patcharin Lapanun
Circular Bioeconomy and Seafood Technology92IMPACT SIGNAL
Comprehensive narrative-review evidence

Crustacean By-Products Hold High-Value Compounds, but ‘Green’ Extraction Still Lacks LCA and Industrial Proof

This review compares conventional acid–alkali and solvent extraction with supercritical fluids, enzymatic hydrolysis, pulsed electric fields, ultrasound, cold plasma, microwave, high-pressure processing, and deep eutectic solvents for recovering bioactives from crustacean by-products. No technology is universally optimal: conventional methods retain advantages in simplicity and maturity, while emerging methods may reduce chemicals or better preserve product quality but face equipment, cost, energy, reproducibility, and pilot-scale constraints. The paper is therefore a map of options and evidence gaps, not proof that one technology is the ‘most sustainable.’

Thai researchersAkanksha R. Gautam · Soottawat Benjakul · Rattikarn Boonchoosri · Nilesh Nirmal · Avtar Singh
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
77IMPACT SIGNAL
Clinical Medicine

Purifying Selection and Interspecific Differentiation at the Myf5 Locus Inform Hybrid Identification and Genetic Management of Thai Clariid Resources

Genes

Thailand-affiliated authors
Phonemany Thammachak · Ton Huu Duc Nguyen · Rinrapat Nitipatpornpanya · Anh Huynh Luu · Edem Uduak Linus · Thitipong Panthum · Kednapat Sriphairoj · Sittichai Hatachote · Satid Chatchaiphan · Chaiwut Grudpan · Jarungjit Grudpan · S. Kiriratnikom · Jiraboon Prasanpan · Orathai Sawatdichaikul · Worapong Singchat · Kornsorn Srikulnath
Institutions
Kasetsart University · Sakon Nakhon Rajabhat University · Ubon Ratchathani University · Thaksin University · Kalasin University
77IMPACT SIGNAL
Clinical Medicine

Long-acting reversible contraceptive use in postpartum and postabortion adolescents: initiation, predictors, and continuation outcomes

Reproductive Health

Thailand-affiliated authors
Paparnin Sangvornrungsie · Nalinee Panichyawat · Thanyarat Wongwananuruk · Nichamon Parkpinyo · Julaporn Pooliam · Marisa Vongsiri · Jaratporn Inthawong
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Proteomic Analysis of Urinary Extracellular Vesicles Reveals Estrogen/Progesterone Status-Associated Biomarkers of Breast Cancer Patients: Potential Roles in Diagnosis and Prognosis

Journal of Health Science and Medical Research

Thailand-affiliated authors
Rassanee Bissanum · Nilobon Jeanmard · Hutcha Sriplung · Sawanya Charoenlappanit · Sittiruk Roytrakul · Raphatphorn Navakanitworakul
Institutions
Prince of Songkla University · National Science and Technology Development Agency
77IMPACT SIGNAL
Clinical Medicine

New Host and Geographic Records of Epifoliar Fungi on Cinnamomum loureiroi from Thailand

Phytotaxa

Thailand-affiliated authors
Asieh Vasighzadeh · Alireza Armand · Ruvishika S. Jayawardena · Kevin D. Hyde
Institutions
Mae Fah Luang University
77IMPACT SIGNAL
Clinical Medicine

Organization of the Digestive Tract and Localization of Protein Fibre in Electrophorus sp. (Gymnotiformes: Gymnotidae)

Acta Zoologica

Thailand-affiliated authors
Sinlapachai Senarat · Narit Thaochan · Kitiya Kongthong · Peerapon Sornying · Piyakorn Boonyoung
Institutions
Prince of Songkla University · Naresuan University
77IMPACT SIGNAL
Clinical Medicine

Multi-Targeted Neuroprotection by Areca catechu Against Cisplatin-Induced Neurotoxicity: Cellular, Caenorhabditis elegans, and Metabolomic Evidence

International Journal of Molecular Sciences

Thailand-affiliated authors
Kishoree Krishna Kumaree · Clerance Su Yee Cheong · Kanika Verma · Kartina Nadyani · Nureesun Mahamud · Pornpimol Mahamad · Tewin Tencomnao · Anchalee Prasansuklab · James Michael Brimson
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Investigation of Cytokine Profiles, the Expression of Genes Involved in Somatic Hypermutation and Peripheral Tolerance, and Their Correlation with Autoantibody Levels in Northern-Thai Immunodeficient Patients Carrying Anti-Interferon-γ Autoantibodies

International Journal of Molecular Sciences

Thailand-affiliated authors
Kritsadee Rattanathammethee · Kriangkrai Chawansuntati · Nongkran Lumjuan · Nattaya Nusartsang · Romanee Chaiwarith · Jutarat Praparattanapan · Khuanchai Supparatpinyo · Jiraprapa Wipasa
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Real-world evidence on off-label underdosing of direct oral anticoagulants in Asian patients with atrial fibrillation: prescribing patterns, determinants, and outcomes

Future Science OA

Thailand-affiliated authors
Supisara Pholprasittito · Supharat Wattanasombat · Natrawee Bureekam
Institutions
Lampang Hospital · ChiangRai Prachanukroh Hospital
77IMPACT SIGNAL
Clinical Medicine

Elevated lipoprotein(a), trimethylamine n-oxide, and gut dysbiosis are associated with subclinical coronary atherosclerosis independent of metabolic dysfunction-associated steatotic liver disease

Scientific Reports

Thailand-affiliated authors
Pairoj Chattranukulchai · Monravee Tumkosit · Pattida Kongsomboonchoke · Pinidphon Prombutara · Anchalee Avihingsanon · Isawan Petchlorlian · Kearkiat Praditpornsilpa · Pisit Tangkijvanich
Institutions
Chulalongkorn University · King Chulalongkorn Memorial Hospital · Thai Red Cross Society · HIV Netherlands Australia Thailand Research Collaboration
77IMPACT SIGNAL
Clinical Medicine

Potent Cross-SerotypeDengue Neutralization with LowADE by AG-Strand-Targeting Anti-EDIII Antibodies

ACS Omega

Thailand-affiliated authors
Napon Nilchan · Anunyaporn Phungsom · Mongkhonphan Tantiwatcharakunthon · Prasit Luangaram · Pattarakul Pakchotanon · Thaneeya Duangchinda · Romchat Kraivong · Tanapan Prommool · Chatchawan Srisawat · Chunya Puttikhunt
Institutions
National Science and Technology Development Agency · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Unexpected diversity of flower-associated Aureobasidium reveals sixteen novel species from northern Thailand

IMA Fungus

Thailand-affiliated authors
Chanokned Senwanna · Pratthana Kodchasee · Chirayut Kathongthung · Milan C. Samarakoon · Pannida Khunnamwong · Jaturong Kumla · Nakarin Suwannarach
Institutions
Chiang Mai University · Kasetsart University
77IMPACT SIGNAL
Clinical Medicine

Becker Muscular Dystrophy with Exon 27-43 Deletion: Clinical andGenetic Insights in a Pediatric Case: A Case Report

Medical Journal of Armed Police Force Nepal

Thailand-affiliated authors
Sri Ram K. C. · Bharat Chand · Drishti Poudel · Prakash Man Shah · Rajani Karki
Institutions
Police General Hospital
77IMPACT SIGNAL
Clinical Medicine

Intelligent Diagnosis of Periapical Pathologies in Dental Radiographs Using an Optimized Triple-Ensemble Deep Learning Framework with Real-World Clinical Validation

Intelligent Systems with Applications

Thailand-affiliated authors
Rapeepan Pitakaso · Kittipit Klanliang · Peerawat Luesak · Sarayut Gonwirat · Chutchai Kaewta · Prem Enkvetchakul · Chawis Boonmee
Institutions
Ubon Ratchathani University · Chiang Mai University · Rajamangala University of Technology Lanna · Kalasin University · Ubon Ratchathani Rajabhat University · Buriram Rajabhat University
77IMPACT SIGNAL
Clinical Medicine

Vitamin D and adverse pathologic features in patients undergoing radical prostatectomy in the contemporary magnetic resonance imaging‐guided management era

BJUI Compass

Thailand-affiliated authors
Sarita Chitjaroen · Kantima Jongjitaree · Varat Woranisarakul · Siros Jitpraphai · Tawatchai Taweemonkongsap · Sunai Leewansangtong · Sittiporn Srinualnad · Thitipat Hansomwong
Institutions
Siriraj Hospital
77IMPACT SIGNAL
Clinical Medicine

Can NEWS predict hospital mortality in patients who left the medical ICU? A retrospective cohort study in resource-limited setting

Annals of critical care

Thailand-affiliated authors
Seksan Chaisuksant · Watchara Boonsawat · Sittichai Khamsai · Kittisak Sawanyawisuth
Institutions
Khon Kaen University
77IMPACT SIGNAL
Clinical Medicine

Acute erythroid leukaemia transformation in polycythaemia vera with leukemic involvement in liver and ascites

BMJ Case Reports

Thailand-affiliated authors
Allison Kaye Lombridas Pagarigan · Natcha Sumpansirikul · Ekapun Karoopongse · Sanya Sukpanichnant
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

SUSTAINED CLINICAL REMISSION AND LONG-TERM SAFETY OF MOLNUPIRAVIR AS FIRST-LINE THERAPY FOR EFFUSIVE FELINE INFECTIOUS PERITONITIS: A 40-WEEK RETROSPECTIVE STUDY

Veterinary and Animal Science

Thailand-affiliated authors
Thiti Surakitkoson · Phuttipan Channgam · Walasinee Sakcamduang · Jeerawat Soonthornsit · Rungrote Osathanon
Institutions
Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Complete mitochondrial genome characterization of the haemosporidian parasite Nycteria heischi in bats Megaderma spasma in Thailand

Current Research in Parasitology and Vector-Borne Diseases

Thailand-affiliated authors
Pattaranatcha Charnwichai · Juthathip Poofery · Dimas Novianto · Siwaporn Tuangpermsub · Thongchai Ngamprasertwong · Morakot Kaewthamasorn
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Accelerating Evidence-Based Practices in Acute Kidney Injury

Clinical Journal of the American Society of Nephrology

Thailand-affiliated authors
Nattachai Srisawat
Institutions
Chulalongkorn University · The Royal College Of Anesthesiologists Of Thailand
77IMPACT SIGNAL
Clinical Medicine

ALY688 confers cardioprotection through macrophage TGFβ-mediated Treg/Th17 dependent multi-organ responses

Pharmacological Research

Thailand-affiliated authors
Sasipat Teerawongsuwan · Ruttachuk Rungsiwiwut · Sivaporn Wannaiampikul
Institutions
Srinakharinwirot University
77IMPACT SIGNAL
Multidisciplinary

Innovative extraction technology and sustainable valorization of industrially-generated longan waste stream

Discover Food

Thailand-affiliated authors
Idris Kaida Zubairu · Noppol Leksawasdi · Sutee Wangtueai · Suphat Phongthai · Abubakar Ibrahim Garba · Yuthana Phimolsiripol
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Effects of a Tubtim Chumphae Rice Extract Facial Serum on Skin Biophysical Properties in Healthy Middle-Aged Adults: A Split-Face Controlled Clinical Trial

Cosmetics

Thailand-affiliated authors
Thapanee Roengrit · Thirapit Subongkot · Thanchanok Sirirak · Suwipa Intakhiao · Jatuporn Phoemsapthawee · Piyapong Prasertsri
Institutions
Suranaree University of Technology · Burapha University · Kasetsart University
77IMPACT SIGNAL
Clinical Medicine

Impact of bacterial infection on native liver survival in children with cirrhosis due to biliary atresia

Clinical and Experimental Pediatrics

Thailand-affiliated authors
Varissara Kaewchaivijit · Pornthep Tanpowpong · Songpon Getsuwan · Sophida Boonsathorn · Chatmanee Lertudomphonwanit · Suporn Treepongkaruna
Institutions
Mahidol University · Ramathibodi Hospital
77IMPACT SIGNAL
Clinical Medicine

Antimicrobial peptide LL-37 promotes proliferation of human bone marrow-derived mesenchymal stem cells

Scientific Reports

Thailand-affiliated authors
Putida Pinthonglor · Pareena Chotjumlong · Dumnoensun Pruksakorn · Jeerawan Klangjorhor · Patcharawadee Thongkumkoon · Worakanya Buranaphatthana · Sarawut Kumphune · Chayarop Supanchart
Institutions
Chiang Mai University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link