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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
Public Health74IMPACT SIGNAL
Evidence of global relevance

Severe Pregnancy-Associated Acute Kidney Injury and Maternal Vulnerability

Electronic records covering 4,094,111 US pregnancies showed severe pregnancy-associated acute kidney injury rising from 9.0 to 27.6 per 10,000 pregnancies between 2012-2013 and the COVID-19 era. Pre-existing cardiometabolic vulnerability was associated with risk, but observational data cannot separate infection, access, testing, and secular trends.

Thai researchersNattachai Srisawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Integrative hematological and transcriptomic analysis reveals monocyte alterations and molecular signatures of inflammatory-coagulation crosstalk in long COVID

A comparison of 21 people with long COVID and 24 asymptomatic controls found lower white-cell, monocyte, and platelet counts and longer APTT. Integrated with a separate public transcriptomic dataset, the findings support a proposed inflammation-coagulation model, but the small and non-identical datasets cannot establish mechanism.

Thai researchersParin Kamseng · Namngern Chantaramanee · Rittikorn Sompan · Sarayot Rareongjai
Public Health74IMPACT SIGNAL
Evidence of global relevance

Toxicological Assessment of Oligofructans Derived from Raw Sugar Fermentation by Bacillus subtilis TISTR 001 and Their Modulatory Effects on Rat Gut Microbiota

Thai researchers evaluated oligofructans produced from raw sugar using Bacillus subtilis TISTR 001. Rats showed no treatment-related mortality or toxicity at doses up to 2,000 mg/kg/day for 90 days, alongside reported shifts in gut microbial taxa. These are preclinical animal findings and do not establish human safety or benefit.

Thai researchersSirinya Taya · Boontiwa Ninchan · Sonthaya Umsumarng · Jutamat Klinsoda · Rawiwan Wongpoomchai · Charatda Punvittayagul
Environment and Engineering74IMPACT SIGNAL
Evidence of global relevance

A Multi-Frequency SAR Framework for Methane Emission Estimation in Thai Rice Paddies

A GISTDA-led framework combines Sentinel-1 and ALOS-2 radar with IPCC accounting to detect crop timing, classify water regimes, and estimate methane from irrigated rice in Thailand's central plain. Mean absolute error was 18.5 kg CH4/ha, but structural uncertainty in the IPCC Tier 1 emission factor exceeded all algorithmic errors combined.

Thai researchersNuntikorn Kitratporn · Kanjana Koedkurang · Panu Nueangjamnong · Kittiphop Simachokchai · Chompunut Chayawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Predictors of Early Recurrence and Survival Outcomes Following Curative Resection for Colorectal Liver Metastases and the Role of Salvage Surgery: A Retrospective Cohort Study

In a retrospective cohort of 109 patients undergoing liver resection for colorectal liver metastases, high tumor burden, major intraoperative blood loss, T3/T4 primary disease, and RAS mutation were associated with early recurrence. Selected patients undergoing salvage re-hepatectomy had favorable long-term survival, but small subgroups and strong selection bias prevent causal conclusions.

Thai researchersPipit Burasakarn · Nisanat Thongkua · Vachiraluck Chalokool · Anuparp Thienhiran · Sermsak Hongjinda · Pusit Fuengfoo
Mental Health74IMPACT SIGNAL
Evidence of global relevance

The Study of Efficacy and Safety of a Modified Chaihu Shugan San Formula in the Treatment of Insomnia Associated with Stress: A Pilot Clinical Evaluation

A 30-participant pre-post pilot reported lower sleep-quality and stress scores after four weeks of twice-daily modified Chaihu Shugan San, without clear liver or renal safety signals. Without randomization, a control group, or placebo, the study cannot separate the formula's effect from placebo, attention, or change over time.

Thai researchersPorwarut Srihara · Cao ZuoJun · Somratchanee Srifar · Mattanapat Phraecharoen
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Benefits of three consecutive sputum inductions using nebulized racemic salbutamol versus hypertonic saline in smear-negative or sputum-scarce pulmonary tuberculosis patients: a prospective randomized, double-blind study

In a randomized double-blind trial of 345 adults with suspected smear-negative or sputum-scarce pulmonary tuberculosis, three consecutive daily inductions with nebulized racemic salbutamol produced a higher combined smear-or-culture yield and fewer adverse events than 3% hypertonic saline. The single-center study evaluates specimen collection for diagnosis, not tuberculosis treatment outcomes.

Thai researchersWarangkana Keeratichananont · Suriya Keeratichananont · Natthaphon Ubonsutvanich · Jirachaya Chaisurote
Thai Fruit and Diabetic Retinal Mechanisms74IMPACT SIGNAL
Evidence of global relevance

ANTIOXIDANT AND ANTI-APOPTOTIC ACTIVITIES OF MAKIANG FRUIT EXTRACT IN ARPE-19 CELLS EXPOSED TO GLUCOSE-INDUCED CELLULAR DAMAGE

A 95% ethanol makiang-fruit extract showed antioxidant activity and, when co-administered in 30 mM glucose-exposed ARPE-19 cells, the highest 200 microgram/mL dose increased viability by 15.4%, reduced ROS by 37.8%, and lowered caspase-9 and -3 activities.

Thai researchersNuntaporn Chanpurk · Kemika Praengam · Angkalsiri Deeaum · Pasitta Panritdum · Monruedee Sukprasansap · Chawanphat Muangnoi
Green-Tea Compounds and Diabetic Kidney Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Epigallocatechin-3-gallate, l-theanine and theophylline abolish high-glucose-induced renal cell senescence and subsequent epithelial-mesenchymal transition and fibroblast activation via SIRT1/PGC-1α axis: Implications for diabetic kidney disease

High glucose induced senescence in proximal tubular cells, whose SASP-conditioned medium then triggered epithelial-mesenchymal transition in distal tubular cells and fibroblast activation. EGCG, L-theanine, and theophylline suppressed these effects while restoring SIRT1/PGC-1alpha signaling.

Thai researchersRattiyaporn Kanlaya · Sunisa Yoodee · Kanokwan Nonthawong · Chonicha Subkod · Supanan Nanthawuttiphan · Visith Thongboonkerd
Curcumin and Breast-Tumor Immunity74IMPACT SIGNAL
Evidence of global relevance

Curcumin Attenuates Breast Cancer Cell-induced Inflammasome Activation via the NOD-like receptor protein 3/Caspase-1/Interleukin-1β Axis

Breast-cancer-cell conditioned medium drove THP-1-derived macrophages toward a pro-inflammatory tumor-associated phenotype with higher IL-1beta, NLRP3, and caspase-1. Curcumin pretreatment reduced IL-1beta secretion, NLRP3 protein, and IL1B/CASP1 transcripts.

Thai researchersKhwandow Kunchana · Wattanased Jarisarapurin · Suvara K. Wattanapitayakul
Encephalitis Viruses and Cell-Death Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Inhibition of calpain-mediated BAX cleavage attenuates Japanese encephalitis virus-induced apoptosis in SH-SY5Y neuroblastoma cells

In SH-SY5Y cells, Japanese encephalitis virus activated calpain to cleave BAX into p18 BAX, which moved to mitochondria and triggered cytochrome c, caspase-3, PARP cleavage, and apoptosis. The calpain inhibitor calpeptin attenuated these signals and improved cell viability.

Thai researchersKuntida Kitidee · Arisara Samutpong · Nattaporn Pakpian · Montri Yasawong · Prapimpun Wongchitrat
Occupational Lung Health and AI Screening74IMPACT SIGNAL
Evidence of global relevance

Artificial neural network modelling using complete blood count for the early detection of black lung disease among Indonesian coal miner: A retrospective longitudinal study

Annual health data from 807 Indonesian coal miners followed from 2013-2021 showed 13.9% cumulative black-lung incidence. A complete-blood-count neural network and Cox model both identified eosinophils and monocytes as influential predictors.

Thai researchersKurnia Ardiansyah Akbar · Kraiwuth Kallawicha · Pallop Siewchaisakul
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
75IMPACT SIGNAL
Clinical Medicine

Single-cell transcriptomic analysis of cutaneous squamous cell carcinoma identifies an NR1H3-associated angiogenic macrophage state

Frontiers in Immunology

Thailand-affiliated authors
Yong He · Ting Tian · Liming Li · Leqi Qian · Tian Tian · Xiaoke Wang · Yuancheng Li · Mingjun Jiang
Institutions
Institute of Dermatology
75IMPACT SIGNAL
Clinical Medicine

Hybrid artificial intelligence framework for patient emotion recognition in dentistry

Frontiers in Oral Health

Thailand-affiliated authors
Kanoksak Wattanachote · Taechinee Ratanawimon · Phawit Phanchantraurai · Wanlida Suphasri-itsara · Panupat Phumpatrakom · Samroeng Inglam · Siriwan Suebnukarn
Institutions
Mahidol University · Thammasat University
75IMPACT SIGNAL
Clinical Medicine

Dual bispecific protein engagers targeting mesothelin and NECTIN2 deliver CD3/CD28 signals to activate cytotoxic T cells against colorectal cancer patient-derived organoids

Scientific Reports

Thailand-affiliated authors
Suyanee Thongchot · Kamonlapat Supimon · Nattaporn Phanthaphol · Pattara Kanoksing · Titaporn Mitchasin · Woramin Riansuwan · Siriluck Prapasrivorakul · Pornraksa Ovartchaiyapong · Aitsariya Mongkhonsupphawan · Surat Phumphuang · Mutita Junking · Pa-thai Yenchitsomanus · Peti Thuwajit · Chanitra Thuwajit
Institutions
Siriraj Hospital · Mahidol University · Naresuan University
75IMPACT SIGNAL
Clinical Medicine

Investigation of the Prevalence of the HLA‐B*15:02 Allele in the Asian Populations: A Comprehensive Analysis Through Using AFND

Health Science Reports

Thailand-affiliated authors
Mohitosh Biswas · Maliheh Ershadian · Chonlaphat Sukasem
Institutions
Mahidol University · Ramathibodi Hospital · Bumrungrad International Hospital
75IMPACT SIGNAL
Clinical Medicine

Inherited C5aR2 deficiency leads to uncontrolled inflammatory T cell responses and autoinflammatory disease 2309676

The Journal of Immunology

Thailand-affiliated authors
Ayden Case · Jubayer Rahman
Institutions
National Institute of Health of Thailand
75IMPACT SIGNAL
Clinical Medicine

Prevention of recurrence of severe combined immunodeficiency through preimplantation genetic testing: a case study of a novel IL2RG variant and confirmed maternal somatic mosaicism in Thailand

Journal of Assisted Reproduction and Genetics

Thailand-affiliated authors
Napadon Yaibuates · Pongpet Benjaponwattana · Busarin Boonyacheeva · Jitti Saksantisuk
Institutions
Nakornthon Hospital · PTT Public Company Limited (Thailand)
75IMPACT SIGNAL
Clinical Medicine

From MyACR to MyμAlbumin: Clinical Validation of a High‐Precision, Real‐Time Immunoturbidimetric PoC Device for Early Chronic Kidney Disease Detection

Journal of Clinical Laboratory Analysis

Thailand-affiliated authors
Tullayakorn Plengsuriyakarn · Wanna Chai่jaroenkul · Napaporn Youngvises · Kridsada Sirisabhabhorn · Waraporn Bubpha · Kesara Na‐Bangchang
Institutions
Thammasat University · Thammasat University Hospital
75IMPACT SIGNAL
Clinical Medicine

Exosomal PD-L1 level in plasma as a predictive marker for prognostic and clinical correlation in NSCLC

Scientific Reports

Thailand-affiliated authors
Krisda Jitrakbumrung · Phuritat Sookananchai · Meena Tanapirakgul · Thutchima Khieota · Poorichaya Somparn · Trairak Pisitkun · Padet Tanangterapong · Panot Sainamthip
Institutions
Chulalongkorn University
75IMPACT SIGNAL
Clinical Medicine

From biological evidence to clinical application: a scoping review of oral fluid biomarkers in type 2 diabetic periodontitis

Frontiers in Oral Health

Thailand-affiliated authors
Sukumaran Anil
Institutions
Chulalongkorn University
75IMPACT SIGNAL
Clinical Medicine

Safety and Immunogenicity of an Additional Dose of Thailand Government Pharmaceutical Organization (GPO) Inactivated NDV-HXP-S COVID-19 Vaccine (HXP-GPOVac) Administered After Primary Vaccination with HXP-GPOVac or BNT162b2: An Open-Label Phase II Extension Trial in Thai Adults

Vaccines

Thailand-affiliated authors
Prabda Praphasiri · Darunee Ditsungneon · Anusak Kerdsin · Sutthichai Nakphook · Jiraphut Kittiwatanachod · Kanlaya Sornwong · Suriya Naosri · Sarunpattori Khunarsa · Ponthip Wirachwong · Isariya Techatanawat · Piengthong Narakorn · Somchaiya Surichan · Chakrarat Pittayawonganon · Sopon Iamsirithaworn · Supakit Sirilak · Kriengkrai Prasert
Institutions
Nakhon Phanom University · Kasetsart University · Sakon Nakhon Rajabhat University · Government of Thailand · Ministry of Public Health · Health Systems Research Institute
75IMPACT SIGNAL
Clinical Medicine

Depression, anxiety, and post-traumatic stress symptoms among wildland firefighters and local residents in recurrent wildfire areas

BMC Psychology

Thailand-affiliated authors
Kanthee Anantapong · Thitiworn Choosong · Siriporn Thaiyapongsakul · Thammasin Ingviya · Udomsak Saengow
Institutions
Prince of Songkla University · Walailak University
75IMPACT SIGNAL
Global Public Health

Treatment reliability of solar septic tank systems under comparative field conditions

Scientific Reports

Thailand-affiliated authors
Tatchai Pussayanavin · Thammarat Koottatep · Sopida Khamyai · Achara Taweesan · Rawintra Eamrat · Chongrak Polprasert
Institutions
Ramkhamhaeng University · Asian Institute of Technology · Thammasat University
75IMPACT SIGNAL
Clinical Medicine

From neuraminidase inhibitors to novel mechanisms: expanding therapeutic strategies against influenza

Frontiers in Cellular and Infection Microbiology

Thailand-affiliated authors
Yan Sun · Puongtip Kunanusorn · Kuang Ming Tup · Bing Yang
Institutions
Krirk University
75IMPACT SIGNAL
Clinical Medicine

Vibrio parahaemolyticusAHPND infection altered eicosanoid biosynthesis in the gastrointestinal tract of Litopenaeus vannamei

Biochemistry and Biophysics Reports

Thailand-affiliated authors
Wananit Wimuttisuk · Pisut Yotbuntueng · Pacharawan Deenarn · Punsa Tobwor · Surasak Jiemsup · Suganya Yongkiettrakul · Kamonluk Kittiwongpukdee · Siriwan Khidprasert · Chanadda Kasamechotchung · Kitlada Srichomthong · Phawit Putprasert
Institutions
National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology · Mahidol University · Rajamangala University of Technology Tawan-ok · Thammasat University
75IMPACT SIGNAL
Clinical Medicine

Experimental and Computational Evaluation of Hybrid Bi2O3/WO3 Nanoparticle-Filled Epoxy Composites for Lead-Free Tc-99m Gamma-Ray Shielding in Occupational Radiation Protection

Polymers

Thailand-affiliated authors
Suphalak Khamruang Marshall · Phuchisa Tepnarin · Wuttipat Wattanaphonpinich · Waritthon Atsawasetthini
Institutions
Prince of Songkla University
75IMPACT SIGNAL
Multidisciplinary

Evidence of Crystallization from Amorphous VOx to VO2 (M1) Thin Film Investigated by in-situ LEEM and NEXAFS Techniques

Chiang Mai Journal of Science

Thailand-affiliated authors
Ukit Rittihong · Napatsakorn Sarapat · Thipusa Wongpinij · Chanan Euaruksakul · Saksorn Limwichean · Mati Horprathum · Prayoon Songsiriritthigul
Institutions
Suranaree University of Technology · Synchrotron Light Research Institute · National Electronics and Computer Technology Center
75IMPACT SIGNAL
Global Public Health

Seasonal transport, retention, and river-to-ocean transfer dynamics of floating macro-debris in the Umgeni River and estuarine lagoon, South Africa

Scientific Reports

Thailand-affiliated authors
Thomas Mani
Institutions
Chulalongkorn University
75IMPACT SIGNAL
Engineering

Characterizing Sensory Drivers of Acceptance, Purchase Intent, and Emotional Responses to Plant-Based Milk Alternatives in Chilled Sweetened Coffee Among Thai Consumers

Foods

Thailand-affiliated authors
Anh Luu Hoang Nguyen · Siriporn Siralertmukul · Sarisuk Sittiketgorn · Aussama Soontrunnarudrungsri · Suntaree Suwonsichon
Institutions
Kasetsart University
75IMPACT SIGNAL
Clinical Medicine

Multifunctional Bacillus Strains for Integrated Fruit Rot Management and Improved Soil Phosphorus Availability in Longan Orchards

Journal of Fungi

Thailand-affiliated authors
Pisi Suksakol · Chananbhorn Thongrote · Tatiya Bansra · Kanlayawat Intha · Jirapinya Liamkraituan · S. Mahadtanapuk
Institutions
University of Phayao · Ministry of Public Health · Kanchanaburi Rajabhat University
75IMPACT SIGNAL
Multidisciplinary

Effects of La2O3 on the Structure and Durability of Alkali Zirconium Silicate Glasses

Chiang Mai Journal of Science

Thailand-affiliated authors
Worapong Thiemsorn · Pinit Kidkhunthod · Nattapol Laorodphan · Ativit Denprawat
Institutions
Chiang Mai University · Synchrotron Light Research Institute · Maejo University
75IMPACT SIGNAL
Global Public Health

Remote Sensing Indices for Drought Characterization in Northeast Thailand: Provisional Descriptive Reference Points and Implications for Drought Monitoring

Sustainability

Thailand-affiliated authors
Narueset Prasertsri · Patiwat Littidej · Benjamabhorn Pumhirunroj
Institutions
Mahasarakham University · Sakon Nakhon Rajabhat University
75IMPACT SIGNAL
Environmental Engineering

Performance and Microstructure Evaluation of Lightweight Low-Heat Roof Tile Using Crushed Coconut Shell as Fine Aggregate

Journal of Materials in Civil Engineering

Thailand-affiliated authors
Tratnaphan Thiparphon · Apichat Suddeepong · Suksun Horpibulsuk · Kongsak Akkharawongwhatthana · Teerasak Yaowarat · Apinun Buritatum
Institutions
Suranaree University of Technology · The Royal College Of Anesthesiologists Of Thailand
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link