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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
STI Treatment and New Antibiotics70IMPACT SIGNAL
Phase 3 non-inferiority evidence

Single-dose oral zoliflodacin was non-inferior to ceftriaxone plus azithromycin for urogenital gonorrhoea

A phase 3 open-label trial at 17 clinics in five countries including Thailand randomized people aged 12+ with suspected uncomplicated urogenital gonorrhoea 2:1 to single oral zoliflodacin 3 g (621) or IM ceftriaxone 500 mg plus oral azithromycin 1 g (309). Day 6±2 microbiological cure in microbiological ITT was 90.9% (460/506) versus 96.2% (229/238). The comparator-minus-zoliflodacin difference was 5.3%, with upper 95% CI 8.6%, below the 12% margin. Events were mostly mild/moderate and no serious events occurred.

Thai researchersRossaphorn Kittiyaowamarn; Nittaya Phanuphak
Theoretical Cosmology71IMPACT SIGNAL
Theoretical model requiring tests

Periodic fractional-action gravity permits cyclic cosmology, with observational support still unclear

The study combines fractional-action cosmology with nonlinear periodic modified gravity in a flat FRW universe. Weighted Friedmann equations define curvature-driven acceleration, with Ricci-scalar oscillations driving expansion-contraction cycles and a fractional parameter controlling amplitude and period. Positive effective coupling and nonnegative scalaron mass support stability for small deviations. Possible star-formation, galaxy, cluster, CMB and primordial-wave signatures are proposed. However, key formulas are missing from the indexed abstract and MCMC/Hubble constraints named in the title are not reported there.

Thai researchersRami Ahmad El-Nabulsi; Waranont Anukool
Geriatric Oral Health71IMPACT SIGNAL
Systematic review and meta-analysis

Low social support is associated with edentulism and irregular dental care after age 75

A PRISMA review searched Medline, Embase and CENTRAL through November 2025 and included 40 studies of adults 75+. Low functional support, or fewer people to rely on, was associated with edentulism (OR 1.21) and irregular dental service use (OR 1.20). Low structural support in living conditions related to edentulism (OR 1.34) and lacking functional dentition (OR 1.41). Other function, behavior and quality-of-life outcomes were sparse and heterogeneous, supporting psychosocial assessment in care planning.

Thai researchersSungkrit Pojmonpiti; Murali Srinivasan; Frauke Müller
Medication and Geriatric Oral Health71IMPACT SIGNAL
Systematic review and meta-analysis

Polypharmacy is associated with roughly twice the odds of dry mouth after age 75

A review screened 3,433 records through April 2025 and included 23 studies: 21 cross-sectional and two cohorts of adults 75+. Polypharmacy was associated with dry mouth (pooled OR 2.05), with consistent links between more medicines, hyposalivation and poor OHAT scores. Multimorbidity was not consistently related to dry mouth or OHAT, and both exposures showed uncertain associations with teeth, edentulism and function. Polypharmacy may affect salivary outcomes partly beyond disease count, but longitudinal evidence is needed.

Thai researchersKittipit Srisanoi; Frauke Müller; Murali Srinivasan
AI Governance and Buddhist Ethics71IMPACT SIGNAL
Qualitative framework evidence

A Buddhist Patisambhida framework recasts university AI governance around purpose, principles, communication and judgment

This qualitative study treats AI as an institutional governance project, not only a teaching or administrative tool. Semistructured interviews with 16 informants, a focus group with nine more participants and document analysis were triangulated. Four themes framed AI as governance and a system-shaping force requiring safeguards, with participant reasoning aligned to Patisambhida: Attha as purpose, Dhamma as principles, Nirutti as communication and Patibhana as judgment, forming a Buddhist Interpretive Governance Framework.

Thai researchersSvangnabha Tuanpusa; Thongdee Sritragarn; Yudthavee Kaewthongyai; Pongpith Tuenpusa
Journal of Interdisciplinary Research in Artificial Intelligence and SocietyRead analysis →
Energy Policy Modeling71IMPACT SIGNAL
National scenario-model evidence

A Thailand 2065 model prioritizes solar, biomass and participation, without yet proving a net-zero pathway

The study develops a GMM-based path model with exogenous variables for Thailand's 2025-2065 policy planning using mixed methods. Technology and energy were most responsive, followed by the social sector. New scenarios emphasize solar adoption, biomass and public participation beyond BCG alone. Final energy use grows 31.75% and GHG emissions 42.35%, or 389.45 MtCO2e, yet the authors classify this below a carrying-capacity threshold and compatible with long-term objectives.

Thai researchersPruethsan Sutthichaimethee; Jindamas Sutthichaimethee; Supakorn Ukumphan; Worawat Sa-Ngiamvibool; Buncha Wattana; Supannika Wattana
AI Literacy and Higher Education71IMPACT SIGNAL
Survey and measurement-model evidence

A four-domain AI-literacy model links use, creation, design and governance with university innovation

Faculty and administrators in private institutions in Sichuan completed a four-domain AILit measure: Engaging, Creating, Designing and Managing. CFA supported reliability (alpha 0.86-0.93); SEM linked all domains to innovation at p0.95, TLI>0.94 and RMSEA

Thai researchersChi Che
Protein Nutrition71IMPACT SIGNAL
Expert critical assessment

Experts pressure-tested common protein claims and found many still under-supported

A February 2025 Indiana University workshop asked over twenty international experts to pressure-test propositions about dietary protein: methodological limitations, ‘optimal’ intake for muscle synthesis, accretion, growth and repair, needs during weight loss, anabolic thresholds and potentially harmful high intakes. Experts rated evidence from strong support to sufficient to rule out. Most propositions required more research because studies lacked rigor, sample size, duration or relied on surrogate outcomes.

Thai researchersWantanee Kriengsinyos
Regional Energy-System Modeling71IMPACT SIGNAL
Systematic modeling review

Asian energy models focus on electricity while underrepresenting long storage, demand and just transition

A systematic review of 97 South and Southeast Asian energy-system modeling studies mapped sectors, time, space, technologies, tools and alignment with national targets. Models overwhelmingly focused on electricity and solar, wind, hydro and biomass. Long-duration storage, carbon removal, demand flexibility, cross-border trade, socioeconomic co-benefits and just-transition metrics were rare. National long-term scales limited subnational and near-term use. India, Indonesia and Vietnam led, while Brunei, Cambodia, Myanmar and Sri Lanka lacked comparable coverage.

Thai researchersFiruz Ahamed Nahid; Ninaad Desai; Joyashree Roy
Climate and Geotechnical Engineering71IMPACT SIGNAL
Field-calibrated simulation evidence

Climate projections suggest shallower wetting in expansive soils and shorter design piers through 2100

Expansive soils shrink and swell with moisture. A finite-element long-term water-migration model was calibrated with laboratory and TRACON building field data at Denver International Airport, then applied to Colorado Front Range profiles through 2100 under SSP1-2.6 and SSP5-8.5. Compared with a traditional climate approach, wetting depth was 4% shallower in shallow clay and 8% in deep clay. Depths were similar between scenarios, but SSP5-8.5 had lower saturation. Air temperature dominated rainfall. Climate-adjusted profiles reduced pier length 3-6% with rigid and 5-12% with elastic design.

Thai researchersKuo Chieh Chao
AI Commerce and Privacy71IMPACT SIGNAL
Survey structural-model evidence

AI personalization may increase travel-platform use despite continuing autonomy and privacy concerns

Using SOR and Psychological Reactance Theory, the study proposes a Threat-Substitution Mechanism for high-involvement online travel decisions. PLS-SEM on 488 Chinese Gen Y/Z OTA users found AI personalization increased usage intention and reduced reactance, with partial mediation. Privacy concern strengthened the negative AIP-reactance relationship, interpreted as heightened threat-appraisal sensitivity rather than uniform resistance.

Thai researchersHongmei Duan; Ahmad Yahya Dawod
Influenza and Antiviral Trials71IMPACT SIGNAL
Prospective kinetics and simulation evidence

Thai adult data estimate a 10.3-hour influenza clearance half-life to guide antiviral trials

Eighty untreated low-risk Thai adults with acute influenza provided duplicate daily oropharyngeal swabs for 14 days with qPCR viral density. Growth-and-decay fit best, while exponential decay was most parsimonious. Median half-life was 10.3 hours: 9.6 for influenza A and 14.0 for B. Simulations suggested 148 per arm gives over 90% power to detect 40% faster clearance; more variability raises sample needs, while four swabs per day could reduce them to 81 per arm at over 80% power.

Thai researchersPhrutsamon Wongnak; Tim Seers; Podjanee Jittamala; Mallika Imwong; William Schilling; Nicholas J. White
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
75IMPACT SIGNAL
Clinical Medicine

Single-cell transcriptomic analysis of cutaneous squamous cell carcinoma identifies an NR1H3-associated angiogenic macrophage state

Frontiers in Immunology

Thailand-affiliated authors
Yong He · Ting Tian · Liming Li · Leqi Qian · Tian Tian · Xiaoke Wang · Yuancheng Li · Mingjun Jiang
Institutions
Institute of Dermatology
75IMPACT SIGNAL
Clinical Medicine

Hybrid artificial intelligence framework for patient emotion recognition in dentistry

Frontiers in Oral Health

Thailand-affiliated authors
Kanoksak Wattanachote · Taechinee Ratanawimon · Phawit Phanchantraurai · Wanlida Suphasri-itsara · Panupat Phumpatrakom · Samroeng Inglam · Siriwan Suebnukarn
Institutions
Mahidol University · Thammasat University
75IMPACT SIGNAL
Clinical Medicine

Dual bispecific protein engagers targeting mesothelin and NECTIN2 deliver CD3/CD28 signals to activate cytotoxic T cells against colorectal cancer patient-derived organoids

Scientific Reports

Thailand-affiliated authors
Suyanee Thongchot · Kamonlapat Supimon · Nattaporn Phanthaphol · Pattara Kanoksing · Titaporn Mitchasin · Woramin Riansuwan · Siriluck Prapasrivorakul · Pornraksa Ovartchaiyapong · Aitsariya Mongkhonsupphawan · Surat Phumphuang · Mutita Junking · Pa-thai Yenchitsomanus · Peti Thuwajit · Chanitra Thuwajit
Institutions
Siriraj Hospital · Mahidol University · Naresuan University
75IMPACT SIGNAL
Clinical Medicine

Investigation of the Prevalence of the HLA‐B*15:02 Allele in the Asian Populations: A Comprehensive Analysis Through Using AFND

Health Science Reports

Thailand-affiliated authors
Mohitosh Biswas · Maliheh Ershadian · Chonlaphat Sukasem
Institutions
Mahidol University · Ramathibodi Hospital · Bumrungrad International Hospital
75IMPACT SIGNAL
Clinical Medicine

Inherited C5aR2 deficiency leads to uncontrolled inflammatory T cell responses and autoinflammatory disease 2309676

The Journal of Immunology

Thailand-affiliated authors
Ayden Case · Jubayer Rahman
Institutions
National Institute of Health of Thailand
75IMPACT SIGNAL
Clinical Medicine

Prevention of recurrence of severe combined immunodeficiency through preimplantation genetic testing: a case study of a novel IL2RG variant and confirmed maternal somatic mosaicism in Thailand

Journal of Assisted Reproduction and Genetics

Thailand-affiliated authors
Napadon Yaibuates · Pongpet Benjaponwattana · Busarin Boonyacheeva · Jitti Saksantisuk
Institutions
Nakornthon Hospital · PTT Public Company Limited (Thailand)
75IMPACT SIGNAL
Clinical Medicine

From MyACR to MyμAlbumin: Clinical Validation of a High‐Precision, Real‐Time Immunoturbidimetric PoC Device for Early Chronic Kidney Disease Detection

Journal of Clinical Laboratory Analysis

Thailand-affiliated authors
Tullayakorn Plengsuriyakarn · Wanna Chai่jaroenkul · Napaporn Youngvises · Kridsada Sirisabhabhorn · Waraporn Bubpha · Kesara Na‐Bangchang
Institutions
Thammasat University · Thammasat University Hospital
75IMPACT SIGNAL
Clinical Medicine

Exosomal PD-L1 level in plasma as a predictive marker for prognostic and clinical correlation in NSCLC

Scientific Reports

Thailand-affiliated authors
Krisda Jitrakbumrung · Phuritat Sookananchai · Meena Tanapirakgul · Thutchima Khieota · Poorichaya Somparn · Trairak Pisitkun · Padet Tanangterapong · Panot Sainamthip
Institutions
Chulalongkorn University
75IMPACT SIGNAL
Clinical Medicine

From biological evidence to clinical application: a scoping review of oral fluid biomarkers in type 2 diabetic periodontitis

Frontiers in Oral Health

Thailand-affiliated authors
Sukumaran Anil
Institutions
Chulalongkorn University
75IMPACT SIGNAL
Clinical Medicine

Safety and Immunogenicity of an Additional Dose of Thailand Government Pharmaceutical Organization (GPO) Inactivated NDV-HXP-S COVID-19 Vaccine (HXP-GPOVac) Administered After Primary Vaccination with HXP-GPOVac or BNT162b2: An Open-Label Phase II Extension Trial in Thai Adults

Vaccines

Thailand-affiliated authors
Prabda Praphasiri · Darunee Ditsungneon · Anusak Kerdsin · Sutthichai Nakphook · Jiraphut Kittiwatanachod · Kanlaya Sornwong · Suriya Naosri · Sarunpattori Khunarsa · Ponthip Wirachwong · Isariya Techatanawat · Piengthong Narakorn · Somchaiya Surichan · Chakrarat Pittayawonganon · Sopon Iamsirithaworn · Supakit Sirilak · Kriengkrai Prasert
Institutions
Nakhon Phanom University · Kasetsart University · Sakon Nakhon Rajabhat University · Government of Thailand · Ministry of Public Health · Health Systems Research Institute
75IMPACT SIGNAL
Clinical Medicine

Depression, anxiety, and post-traumatic stress symptoms among wildland firefighters and local residents in recurrent wildfire areas

BMC Psychology

Thailand-affiliated authors
Kanthee Anantapong · Thitiworn Choosong · Siriporn Thaiyapongsakul · Thammasin Ingviya · Udomsak Saengow
Institutions
Prince of Songkla University · Walailak University
75IMPACT SIGNAL
Global Public Health

Treatment reliability of solar septic tank systems under comparative field conditions

Scientific Reports

Thailand-affiliated authors
Tatchai Pussayanavin · Thammarat Koottatep · Sopida Khamyai · Achara Taweesan · Rawintra Eamrat · Chongrak Polprasert
Institutions
Ramkhamhaeng University · Asian Institute of Technology · Thammasat University
75IMPACT SIGNAL
Clinical Medicine

From neuraminidase inhibitors to novel mechanisms: expanding therapeutic strategies against influenza

Frontiers in Cellular and Infection Microbiology

Thailand-affiliated authors
Yan Sun · Puongtip Kunanusorn · Kuang Ming Tup · Bing Yang
Institutions
Krirk University
75IMPACT SIGNAL
Clinical Medicine

Vibrio parahaemolyticusAHPND infection altered eicosanoid biosynthesis in the gastrointestinal tract of Litopenaeus vannamei

Biochemistry and Biophysics Reports

Thailand-affiliated authors
Wananit Wimuttisuk · Pisut Yotbuntueng · Pacharawan Deenarn · Punsa Tobwor · Surasak Jiemsup · Suganya Yongkiettrakul · Kamonluk Kittiwongpukdee · Siriwan Khidprasert · Chanadda Kasamechotchung · Kitlada Srichomthong · Phawit Putprasert
Institutions
National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology · Mahidol University · Rajamangala University of Technology Tawan-ok · Thammasat University
75IMPACT SIGNAL
Clinical Medicine

Experimental and Computational Evaluation of Hybrid Bi2O3/WO3 Nanoparticle-Filled Epoxy Composites for Lead-Free Tc-99m Gamma-Ray Shielding in Occupational Radiation Protection

Polymers

Thailand-affiliated authors
Suphalak Khamruang Marshall · Phuchisa Tepnarin · Wuttipat Wattanaphonpinich · Waritthon Atsawasetthini
Institutions
Prince of Songkla University
75IMPACT SIGNAL
Multidisciplinary

Evidence of Crystallization from Amorphous VOx to VO2 (M1) Thin Film Investigated by in-situ LEEM and NEXAFS Techniques

Chiang Mai Journal of Science

Thailand-affiliated authors
Ukit Rittihong · Napatsakorn Sarapat · Thipusa Wongpinij · Chanan Euaruksakul · Saksorn Limwichean · Mati Horprathum · Prayoon Songsiriritthigul
Institutions
Suranaree University of Technology · Synchrotron Light Research Institute · National Electronics and Computer Technology Center
75IMPACT SIGNAL
Global Public Health

Seasonal transport, retention, and river-to-ocean transfer dynamics of floating macro-debris in the Umgeni River and estuarine lagoon, South Africa

Scientific Reports

Thailand-affiliated authors
Thomas Mani
Institutions
Chulalongkorn University
75IMPACT SIGNAL
Engineering

Characterizing Sensory Drivers of Acceptance, Purchase Intent, and Emotional Responses to Plant-Based Milk Alternatives in Chilled Sweetened Coffee Among Thai Consumers

Foods

Thailand-affiliated authors
Anh Luu Hoang Nguyen · Siriporn Siralertmukul · Sarisuk Sittiketgorn · Aussama Soontrunnarudrungsri · Suntaree Suwonsichon
Institutions
Kasetsart University
75IMPACT SIGNAL
Clinical Medicine

Multifunctional Bacillus Strains for Integrated Fruit Rot Management and Improved Soil Phosphorus Availability in Longan Orchards

Journal of Fungi

Thailand-affiliated authors
Pisi Suksakol · Chananbhorn Thongrote · Tatiya Bansra · Kanlayawat Intha · Jirapinya Liamkraituan · S. Mahadtanapuk
Institutions
University of Phayao · Ministry of Public Health · Kanchanaburi Rajabhat University
75IMPACT SIGNAL
Multidisciplinary

Effects of La2O3 on the Structure and Durability of Alkali Zirconium Silicate Glasses

Chiang Mai Journal of Science

Thailand-affiliated authors
Worapong Thiemsorn · Pinit Kidkhunthod · Nattapol Laorodphan · Ativit Denprawat
Institutions
Chiang Mai University · Synchrotron Light Research Institute · Maejo University
75IMPACT SIGNAL
Global Public Health

Remote Sensing Indices for Drought Characterization in Northeast Thailand: Provisional Descriptive Reference Points and Implications for Drought Monitoring

Sustainability

Thailand-affiliated authors
Narueset Prasertsri · Patiwat Littidej · Benjamabhorn Pumhirunroj
Institutions
Mahasarakham University · Sakon Nakhon Rajabhat University
75IMPACT SIGNAL
Environmental Engineering

Performance and Microstructure Evaluation of Lightweight Low-Heat Roof Tile Using Crushed Coconut Shell as Fine Aggregate

Journal of Materials in Civil Engineering

Thailand-affiliated authors
Tratnaphan Thiparphon · Apichat Suddeepong · Suksun Horpibulsuk · Kongsak Akkharawongwhatthana · Teerasak Yaowarat · Apinun Buritatum
Institutions
Suranaree University of Technology · The Royal College Of Anesthesiologists Of Thailand
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link