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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
Geospatial Agriculture and Environment89IMPACT SIGNAL
Regional model-validation evidence

GEDI–Sentinel Model Maps Northeast Thai Rubber at 82.63% Accuracy but Struggles With Young Plantations

This study mapped 2024 rubber distribution and age structure across Northeast Thailand using Random Forest in Google Earth Engine, combining Sentinel-1, Sentinel-2, vegetation indices, and a GEDI-trained canopy-height model. Three-class rubber mapping reached 82.63% overall accuracy and about 0.84 F1; three-group age classification reached 83.39%. Plantations older than seven years dominated and were classified more reliably than young stands. The output is a regional monitoring baseline, not an error-free parcel-level decision map.

Thai researchersSavittri Ratanopad Suwanlee · Muhammad Hanif · Surasak Keawsomsee · Kemin Kasa · Narissara Nuthammachot · Sarawut Ninsawat · Jantima Polpinij · Jaturong Som-Ard
Medical Education and Serious-Illness Care89IMPACT SIGNAL
Longitudinal training evidence

Advance-Care-Planning Training Raised Residents’ Knowledge From 7.74 to 8.65, but Had No Control Group

This mixed-methods evaluation tested an Advance Care Planning programme combining role-play, personal-value reflection, and two Circle of Learning sessions with an entire cohort of 50 first-year internal-medicine residents. Longitudinal analysis used 34 complete cases through 15 months, and 10 residents were interviewed. Knowledge rose from 7.74 to 8.65 out of 9, alongside several attitude and confidence improvements. Interviewees said role-play bridged theory and practice but identified a need for ongoing workplace support. The evidence concerns learner readiness, not observed conversation quality or patient outcomes.

Thai researchersThagoon Kanjanopas · Smuch Siramongkholkarn · Wanna Jarusomboon · Ekkapop Sittiwantana · Arisa Phochaisarn · Saipin Hathirat · Saran Thanapluetiwong
Public Health and Migrant Health92IMPACT SIGNAL
Evidence of global relevance

Migrant TB Patients Chose Months-Long Sanatorium Care to Pursue Cure Amid Cost, Transport, and Documentation Barriers

This multi-perspective qualitative study at the SMRU tuberculosis sanatorium in Mae Ramat, Tak Province, examined why migrants choose long residential treatment. It included 37 unique patients—33 who chose the sanatorium and four who chose community DOTS—plus five health workers. Three themes organized the findings: desire for cure, barriers to diagnosis and treatment, and community and organizational support.

Thai researchersJindaporn Wirachonphaophong · Hai Ti Ti · Nay Kaw Htoo · Kanjana Winyoorat · Cha Ba · San Soe · Suphak Nosten · Htet Ko Ko Aung · Sein Sein Thi · Francois Nosten
Public Health and Health Systems92IMPACT SIGNAL
Qualitative evidence for service design

Patients in South Ethiopia Know How to Manage Diabetes, but Drug Shortages and Costs Undercut Self-Care

This qualitative study examined diabetes self-care in three South Ethiopian hospital clinics. Its 21 participants comprised 12 adults with type 2 diabetes and nine healthcare providers. Patients described medication, diet, physical activity, foot care, and glucose monitoring as daily work negotiated against financial pressure, drug shortages, beliefs, food costs, limited support, and health-system constraints. Patients tended to foreground structural barriers, whereas providers placed more emphasis on knowledge and forgetting advice. Continued counselling, reliable medicines, and peer support emerged as priorities, but these are interview-derived design directions rather than tested interventions.

Thai researchersTemesgen Anjulo Ageru · Cua Ngoc Le · Apichai Wattanapisit · Charuai Suwanbamrung
International Journal of Qualitative Studies on Health and Well-beingRead analysis →
Forest Policy and Bioeconomy92IMPACT SIGNAL
Evidence of global relevance

Perspectives on the forest bioeconomy: insights of stakeholders from cases in Central Europe and the Mekong region

This comparative study examines how 336 purposively recruited respondents in Czechia, Slovakia, Thailand, Laos and Vietnam understand and assess the forest bioeconomy. Respondents generally reported stronger familiarity with sustainable forest management and the circular economy than with the bioeconomy itself. Perceptions also varied across country cases, particularly within the Mekong region. A binary logistic regression identified associations between high perceived implementation and country, age, education, understanding of policy aims, support for implementation and positive assessments of forest-industry implementation. These findings describe perceptions within the recruited sample rather than national populations, and the reported associations should not be interpreted as causal effects.

Thai researchersNopparat Kaakkurivaara · Alice Sharp · Prasit Wangpakapattanawong
One Health and Zoonotic-Disease Prevention92IMPACT SIGNAL
Formative evidence for One Health intervention design

Zoonotic Risk in Rural Nan Is Not Just Behavioural: Water Scarcity, Forest Change, and Food Systems Connect Five Interfaces

Researchers examined everyday practices and conditions that could enable cross-species transmission in four rural villages in Nan Province, organising findings into five interfaces: human–animal, human–environment, human-human, animal–animal, and animal–environment. The picture is not simply one of deficient knowledge. Animal contact, butchering and food preparation, water scarcity and contamination, waste, forest change, intensified agriculture, mixed-species proximity, and multilingual communication operate as a system. Community leaders and village health volunteers were viewed as trusted messengers. The study therefore recommends education that combines knowledge, skills, practical tools, and recognition of structural limits, but it neither completed nor evaluated the final intervention.

Thai researchersMonchai Phongsiri · Simaphon Tomklang · Theerayuth Labooth · Thanapat Chaibut · Pongsakon Jaruton · Kotthamon Chanprathad · Sarutaya Suphawatthanaphan · Hans Overgaard · Patcharin Lapanun
Circular Bioeconomy and Seafood Technology92IMPACT SIGNAL
Comprehensive narrative-review evidence

Crustacean By-Products Hold High-Value Compounds, but ‘Green’ Extraction Still Lacks LCA and Industrial Proof

This review compares conventional acid–alkali and solvent extraction with supercritical fluids, enzymatic hydrolysis, pulsed electric fields, ultrasound, cold plasma, microwave, high-pressure processing, and deep eutectic solvents for recovering bioactives from crustacean by-products. No technology is universally optimal: conventional methods retain advantages in simplicity and maturity, while emerging methods may reduce chemicals or better preserve product quality but face equipment, cost, energy, reproducibility, and pilot-scale constraints. The paper is therefore a map of options and evidence gaps, not proof that one technology is the ‘most sustainable.’

Thai researchersAkanksha R. Gautam · Soottawat Benjakul · Rattikarn Boonchoosri · Nilesh Nirmal · Avtar Singh
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
74IMPACT SIGNAL
Clinical Medicine

Ambient PM2.5 and respiratory tract disorder–related outpatient visits among healthcare workers: an ecological time-series study

BMC Public Health

Thailand-affiliated authors
Chaturon Tangsangwornthamma · Sivakorn Suntinipanon · Chathaya Wongrathanandha · Natnaree Aimyong
Institutions
Ramathibodi Hospital · Mahidol University
74IMPACT SIGNAL
Clinical Medicine

Clinical Prognostic Factors and Survival Risk Stratification for Advanced Biliary Tract Cancer Treated with Gemcitabine-Based Palliative Chemotherapy: A Real-World Retrospective Study

Life

Thailand-affiliated authors
Jirapat Wonglhow · Arunee Dechaphunkul · Patrapim Sunpaweravong · Chirawadee Sathitruangsak · Panu Wetwittayakhlang
Institutions
Prince of Songkla University
74IMPACT SIGNAL
Clinical Medicine

A Proteomic Study Reveals the Relationship Between Arterial Stiffness and Hyperglycemia in Middle-Aged Obese Men

Clinical Diabetology

Thailand-affiliated authors
Thanutchaporn Nutmakul · Nontawit Auppawat · Sittiruk Roytrakul · Jintana Sirivarasai · Sirasa Ruangritchankul · Wutarak Monsuwan
Institutions
Ramathibodi Hospital · National Science and Technology Development Agency
74IMPACT SIGNAL
Clinical Medicine

Skipjack tuna bone-derived biocalcium ameliorates osteoblast and osteoclast differentiation through microRNA21 regulation

iScience

Thailand-affiliated authors
Sompot Jantarawong · Sudarat Phuntong · Saowapak Kanobthammakul · Papitchaya Watcharanurak · Jidapa Szekely · Jedsada Kaewrakmuk · Eakolarn Chotianuson · Doungporn Amornlerdpison · Chutima S. Vaddhanaphuti · Theeraphol Senphan · Yutthana Pengjam
Institutions
Prince of Songkla University · Suan Sunandha Rajabhat University · Maejo University · Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Effects of Fine Particulate Matter on Systemic Inflammatory Biomarkers in Elderly Patients with Chronic Obstructive Pulmonary Disease Versus the Healthy Elderly: A Pilot Study

International Journal of Molecular Sciences

Thailand-affiliated authors
Warawut Chaiwong · Chalerm Liwsrisakun · Pilaiporn Duangjit · Juthamas Inchai · Chaiwat Bumroongkit · Athavudh Deesomchok · Theerakorn Theerakittikul · Atikun Limsukon · Pattraporn Tajarernmuang · Nutchanok Niyatiwatchanchai · Konlawij Trongtrakul · Chittrawadee Chitchun · Nipon Chattipakorn · Siriporn C. Chattipakorn · Nattayaporn Apaijai · Chaicharn Pothirat
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine

Abalone-derived dermatopontin and its RFK-containing peptide promote osteogenesis via TGF-β/Smad signaling pathway

International Journal of Biological Macromolecules

Thailand-affiliated authors
Purimpuch Soongnart · Supawich Boonkua · Orawan Thongsum · Rueangtip Chantunmapitak · Primwadee Wichienwat · Pan Soonsawad · Wattana Weerachatyanukul · Aungkura Supokawej · Somluk Asuvapongpatana
Institutions
Mahidol University · Thammasat University · Mahamakut Buddhist University
74IMPACT SIGNAL
Multidisciplinary

Nanoclay, calcium alginate, and composite soil amendments mitigate drought effects on wheat growth and water-use efficiency

Frontiers in Plant Science

Thailand-affiliated authors
Khalifa M. Alteneiji · Razan F. Alhammadi · Lamya Alsuwaidi · Walid Abo Baker · Mohammad A. Al-Faqieh
Institutions
Department of Livestock Development
74IMPACT SIGNAL
Clinical Medicine

Organic UV Filter Exposure in Children of Indonesia, Thailand, and Saudi Arabia – Urinary Concentrations, Risks, and Potential Sources

Integrated Environmental Assessment and Management

Thailand-affiliated authors
Kraichat Tantrakarnapa · Wissanupong Kliengchuay
Institutions
Mahidol Oxford Tropical Medicine Research Unit
74IMPACT SIGNAL
Clinical Medicine

Investigation of Oncogenic Gene Mutation and Associated Protein Expression in Ameloblastic Carcinoma

Oral Diseases

Thailand-affiliated authors
Puangwan Lapthanasupkul · Jintana Pankam · Siribang-on Piboonniyom Khovidhunkit · Prapapun Seneetuntigul · Nakarin Kitkumthorn
Institutions
Mahidol University · Ministry of Public Health · Burapha University
74IMPACT SIGNAL
Clinical Medicine

Late-follicular androgen and estrogen rise associated with clinical pregnancy in IVF/ICSI with granulosa cell studies

Reproduction and Fertility

Thailand-affiliated authors
Rungnapa Sririwichitchai · Chantacha Sitticharoon · Issarawan Keadkraichaiwat · Pailin Maikaew · Suchawadee Chanheng · Somsin Petyim
Institutions
Siriraj Hospital
74IMPACT SIGNAL
Clinical Medicine

Combined podocyte, fibrotic and echocardiographic correlates of an operationally defined subclinical cardiorenal phenotype in chronic kidney disease: an exploratory study

Renal Failure

Thailand-affiliated authors
Ulugbek Ochilov
Institutions
Asia Pacific International University
73IMPACT SIGNAL
Global Public Health

Distinctive Patterns of Gut Bifidobacterium Diversity in Mongolian Adults: Regional Variation and Dairy Intake Associations

Nutrients

Thailand-affiliated authors
Sabri Bromage
Institutions
Mahidol University
73IMPACT SIGNAL
Clinical Medicine

Efficacy and Safety of Phikud Tri-Phon Herbal Decoction for Weight Management in Young Adult Thai Females: A Double-Blind, Randomized Controlled Trial

International Journal of Environmental Research and Public Health

Thailand-affiliated authors
Naparat Doungchan · Marisa Poomiphak Na Nongkhai · Sulukkana Noiprasert · Ngamrayu Ngamdokmai
Institutions
Walailak University · Mae Fah Luang University · Burapha University
73IMPACT SIGNAL
Global Public Health

Spatial determinants of disability prevalence in myanmar: A district-level spatial regression analysis

Journal of Public Health and Development

Thailand-affiliated authors
Wor Mi Thi · Kyaw Min Htike
Institutions
Khon Kaen University
73IMPACT SIGNAL
Clinical Medicine

Faecal microbiota transplantation for skin disease: intriguing biology, premature therapy?

British Journal of Dermatology

Thailand-affiliated authors
John A. McGrath
Institutions
Institute of Dermatology
73IMPACT SIGNAL
Global Public Health

Impact of pedigree completeness on genomic–polygenic evaluations for milk yield, fat percentage, and age at first calving in Thai multibreed dairy cattle

Archives animal breeding/Archiv für Tierzucht

Thailand-affiliated authors
Danai Jattawa · Praew Thiengpimol · Thanathip Suwanasopee · Thawee Laodim · Skorn Koonawootrittriron
Institutions
Kasetsart University · Thammasat University
73IMPACT SIGNAL
Digital Health

Machine learning-based solar radiation prediction across heterogeneous climatic zones using NASA POWER data: a case study in Nigeria

Frontiers in Artificial Intelligence

Thailand-affiliated authors
Laemthong Laokhongthavorn · Viroon Kamchoom
Institutions
King Mongkut's Institute of Technology Ladkrabang
73IMPACT SIGNAL
Global Public Health

The Future of Suvanrnabhumi Airport as an Air Logistics Hub in Southeast Asia

TEM Journal

Thailand-affiliated authors
Kritsana Lakkhongkha · Akkarat Poolkrajang · Pusit Pupapassiri · Ratchapol Kladchuen
Institutions
Mahidol University · Rajamangala University of Technology · Bangkok University · Nakhon Pathom Rajabhat University
73IMPACT SIGNAL
Clinical Medicine

Integrated Phytochemical Characterization, Formulation Engineering, and Stability Assessment of a Spray-Based Dermocosmetic Delivery System Incorporating Plectranthus amboinicus Leaf Extract

Cosmetics

Thailand-affiliated authors
Nustha Kitprathaung · P. Poungthong
Institutions
Shinawatra University · King Mongkut's Institute of Technology Ladkrabang
73IMPACT SIGNAL
Clinical Medicine

The Role of Mesenchymal Stem Cells in Regenerative Medicine: From Biology to Clinical Applications

Indonesian Journal of Biotechnology (Universitas Gadjah Mada)

Thailand-affiliated authors
Đăng Quỳnh Lê
Institutions
Chulalongkorn University
73IMPACT SIGNAL
Clinical Medicine

Dicharax pallgergelyi Jirapatrasilp & Inkhavilay 2026, sp. nov.

Open MIND

Thailand-affiliated authors
Parin Jirapatrasilp · Teerangkul Janjai · Ekgachai Jeratthitikul · Natdanai Likhitrakarn · Ruttapon Srisonchai · Chirasak Sutcharit
Institutions
Chulalongkorn University · Mahidol University · Maejo University · Khon Kaen University
73IMPACT SIGNAL
Multidisciplinary

Metalycaeus Pilsbry 1900

Open MIND

Thailand-affiliated authors
Parin Jirapatrasilp · Teerangkul Janjai · Ekgachai Jeratthitikul · Natdanai Likhitrakarn · Ruttapon Srisonchai · Chirasak Sutcharit
Institutions
Chulalongkorn University · Mahidol University · Maejo University · Khon Kaen University
73IMPACT SIGNAL
Clinical Medicine

Safety and Efficacy of a Hydrolyzed Collagen Formulation (HYCOS) for Facial Skin Elasticity and Wrinkles: A Randomized, Double‐Blind, Placebo‐Controlled Trial

Journal of Cosmetic Dermatology

Thailand-affiliated authors
Sutthinee Wisutthathum · Preeyanuch Pimjuk · Nitina Yeesibsean · Katechan Jampachaisri · Panlop Chakkavittumrong · Warisara Pasri · Pichet Kittikun · Supaporn Tuanthai · Thanwarat Suebwongfag · Tanyarat Sutti · Anjana Fuangchan · Neti Waranuch
Institutions
Naresuan University · Thammasat University
73IMPACT SIGNAL
Clinical Medicine

A new species of the Ovophis tonkinensis species complex (Serpentes, Viperidae) from the Langbian Plateau, southern Vietnam

Herpetozoa

Thailand-affiliated authors
Parinya Pawangkhanant · Chatmongkon Suwannapoom
Institutions
University of Phayao
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link