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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

1,027 analyses
Mental Health74IMPACT SIGNAL
Evidence of global relevance

The Study of Efficacy and Safety of a Modified Chaihu Shugan San Formula in the Treatment of Insomnia Associated with Stress: A Pilot Clinical Evaluation

A 30-participant pre-post pilot reported lower sleep-quality and stress scores after four weeks of twice-daily modified Chaihu Shugan San, without clear liver or renal safety signals. Without randomization, a control group, or placebo, the study cannot separate the formula's effect from placebo, attention, or change over time.

Thai researchersPorwarut Srihara · Cao ZuoJun · Somratchanee Srifar · Mattanapat Phraecharoen
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Benefits of three consecutive sputum inductions using nebulized racemic salbutamol versus hypertonic saline in smear-negative or sputum-scarce pulmonary tuberculosis patients: a prospective randomized, double-blind study

In a randomized double-blind trial of 345 adults with suspected smear-negative or sputum-scarce pulmonary tuberculosis, three consecutive daily inductions with nebulized racemic salbutamol produced a higher combined smear-or-culture yield and fewer adverse events than 3% hypertonic saline. The single-center study evaluates specimen collection for diagnosis, not tuberculosis treatment outcomes.

Thai researchersWarangkana Keeratichananont · Suriya Keeratichananont · Natthaphon Ubonsutvanich · Jirachaya Chaisurote
Thai Fruit and Diabetic Retinal Mechanisms74IMPACT SIGNAL
Evidence of global relevance

ANTIOXIDANT AND ANTI-APOPTOTIC ACTIVITIES OF MAKIANG FRUIT EXTRACT IN ARPE-19 CELLS EXPOSED TO GLUCOSE-INDUCED CELLULAR DAMAGE

A 95% ethanol makiang-fruit extract showed antioxidant activity and, when co-administered in 30 mM glucose-exposed ARPE-19 cells, the highest 200 microgram/mL dose increased viability by 15.4%, reduced ROS by 37.8%, and lowered caspase-9 and -3 activities.

Thai researchersNuntaporn Chanpurk · Kemika Praengam · Angkalsiri Deeaum · Pasitta Panritdum · Monruedee Sukprasansap · Chawanphat Muangnoi
Green-Tea Compounds and Diabetic Kidney Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Epigallocatechin-3-gallate, l-theanine and theophylline abolish high-glucose-induced renal cell senescence and subsequent epithelial-mesenchymal transition and fibroblast activation via SIRT1/PGC-1α axis: Implications for diabetic kidney disease

High glucose induced senescence in proximal tubular cells, whose SASP-conditioned medium then triggered epithelial-mesenchymal transition in distal tubular cells and fibroblast activation. EGCG, L-theanine, and theophylline suppressed these effects while restoring SIRT1/PGC-1alpha signaling.

Thai researchersRattiyaporn Kanlaya · Sunisa Yoodee · Kanokwan Nonthawong · Chonicha Subkod · Supanan Nanthawuttiphan · Visith Thongboonkerd
Curcumin and Breast-Tumor Immunity74IMPACT SIGNAL
Evidence of global relevance

Curcumin Attenuates Breast Cancer Cell-induced Inflammasome Activation via the NOD-like receptor protein 3/Caspase-1/Interleukin-1β Axis

Breast-cancer-cell conditioned medium drove THP-1-derived macrophages toward a pro-inflammatory tumor-associated phenotype with higher IL-1beta, NLRP3, and caspase-1. Curcumin pretreatment reduced IL-1beta secretion, NLRP3 protein, and IL1B/CASP1 transcripts.

Thai researchersKhwandow Kunchana · Wattanased Jarisarapurin · Suvara K. Wattanapitayakul
Encephalitis Viruses and Cell-Death Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Inhibition of calpain-mediated BAX cleavage attenuates Japanese encephalitis virus-induced apoptosis in SH-SY5Y neuroblastoma cells

In SH-SY5Y cells, Japanese encephalitis virus activated calpain to cleave BAX into p18 BAX, which moved to mitochondria and triggered cytochrome c, caspase-3, PARP cleavage, and apoptosis. The calpain inhibitor calpeptin attenuated these signals and improved cell viability.

Thai researchersKuntida Kitidee · Arisara Samutpong · Nattaporn Pakpian · Montri Yasawong · Prapimpun Wongchitrat
Occupational Lung Health and AI Screening74IMPACT SIGNAL
Evidence of global relevance

Artificial neural network modelling using complete blood count for the early detection of black lung disease among Indonesian coal miner: A retrospective longitudinal study

Annual health data from 807 Indonesian coal miners followed from 2013-2021 showed 13.9% cumulative black-lung incidence. A complete-blood-count neural network and Cox model both identified eosinophils and monocytes as influential predictors.

Thai researchersKurnia Ardiansyah Akbar · Kraiwuth Kallawicha · Pallop Siewchaisakul
Rational Prescribing and Medication Safety74IMPACT SIGNAL
Evidence of global relevance

Assessment of Inappropriate Omeprazole Prescribing, Associated Factors and Financial Impact in the Outpatient Department of a General Hospital in Thailand

A review of 347 outpatient prescriptions for 229 patients from January-June 2025 at one Thai general hospital classified 58.2% of omeprazole prescriptions as potentially inappropriate. Of these, 75.2% lacked an appropriate indication, followed by inappropriate duration.

Thai researchersSaranporn Srithonrat · Chayanat Pongsathabordee · Satawat Kulworahathai · Chidawan Prapat · Aticha Jamratkittiwan · Nichakan Jitakson · Taniya Paiboonvong
Endocrine Emergency Medicine74IMPACT SIGNAL
Evidence of global relevance

Prognostic factors and prognostic risk score of 30-day all-cause mortality in thyroid storm

A retrospective cohort of 115 thyroid-storm patients at a Thai tertiary center had 13% 30-day mortality. An eight-point score using male sex, hypertension, SOFA at least 2, and GCS at most 10 achieved apparent AUC 0.81 and bootstrap-corrected AUC 0.79.

Thai researchersPakpoom Chantrapitak · Worapaka Manosroi · Sittikul Thipbumrung · Pichitchai Atthakomol
Companion-Animal AMR and One Health74IMPACT SIGNAL
Evidence of global relevance

Genomic Characterization, Antimicrobial Resistance Profiles, and tetA Nucleotide Substitutions of Escherichia coli Isolated from Healthy Dogs in Thailand

Fecal samples from 200 healthy dogs at 50 clinics in Chiang Mai and Nakhon Si Thammarat during January-March 2026 yielded 66 E. coli isolates. Resistance reached 100% for ampicillin, 84.85% for piperacillin, 60.61% for ceftriaxone, 56.06% for tetracycline, and 47% multidrug resistance.

Thai researchersRavisa Warin · Naparat Suttidate · Wanna Suriyasathaporn · Witaya Suriyasathaporn · Ratchadaporn Boripun
Microalgae and Energy Harvesting74IMPACT SIGNAL
Evidence of global relevance

Immobilized microalgae-driven triboelectric nanogenerators for sustainable bioelectricity production

Thai researchers immobilized living Chlorella vulgaris TISTR 8580 at different densities on aluminum electrodes as a triboelectric layer for solid-solid and solid-liquid interactions, reporting peak output of 110 V and 330 nA.

Thai researchersChalampol Janpum · Tanakit Komkhum · Naratip Vittayakorn · Kamon Thinsurat · Chawalit Ngamcharussrivichai · Pichaya In-na
Alternative Proteins, Drying, and Flavor73IMPACT SIGNAL
Evidence of global relevance

Drying-Induced Structural and Oxidative Transformations in Sustainable Proteins: Impact on Physicochemical Properties and Flavor-Binding Functionality

This review proposes a structure-process-function framework explaining how hot-air, heat-pump, microwave, and freeze-drying differently unfold, aggregate, and oxidize plant and marine proteins, changing how volatile flavors are bound, retained, and released.

Thai researchersYoon Hlaine Barani · Passakorn Kingwascharapong · Saroat Rawdkuen
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

2,955records
2,955 records
77IMPACT SIGNAL
Clinical Medicine

Efficacy and safety of tocilizumab for refractory postsurgical cystoid macular edema

Journal of Ophthalmic Inflammation and Infection

Thailand-affiliated authors
Prapatsorn Ongpalakorn
Institutions
Nopparat Rajathanee Hospital
77IMPACT SIGNAL
Multidisciplinary

A Hierarchical Computer Vision Framework for Continuous Dairy Cow Behavior Monitoring in an Obstructed Free-Stall Barns

Smart Agricultural Technology

Thailand-affiliated authors
Aqeel Raza · Kumail Abbas · H. Hogeveen · Chaidate Inchaisri
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Metabolomic and lipidomic analyses reveal phosphatidylcholine–lysophosphatidylcholine axis alterations in sorafenib-persistent hepatocellular carcinoma

Biomedicine & Pharmacotherapy

Thailand-affiliated authors
Meng Chieh Yang · Nichawadee Sandech · Sucheewin Krobthong · Likit Rangsirattanakul · Wisuit Pradidarcheep · Arnatchai Maiuthed
Institutions
Srinakharinwirot University · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Patient safety events and outcomes in brain tumor surgery : A retrospective cohort study

Journal of Neurosciences in Rural Practice

Thailand-affiliated authors
Kanisorn Sungkaro · Pannawit Chumchue · Thara Tunthanathip · Supaporn Sainamsai
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Development and evaluation of a drug–herb interaction alert system integrated into a hospital electronic health record

Pharmacia

Thailand-affiliated authors
Thanatcha Songmuang · Ananya Songmuang · Chonladda Pitchayajittipong · Teeraporn Sadira Supapaan
Institutions
Warin Chamrap Hospital · Ubon Ratchathani University
77IMPACT SIGNAL
Clinical Medicine

Association of adipocyte hypertrophy and ultrasound severity score in lymphedematous limb: a cross-sectional study

Scientific Reports

Thailand-affiliated authors
Parkpoom Piyaman · Panitta Sitthinamsuwan · Sirin Apichonbancha · Nutcha Yodrabum
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Phosphoprotein-enriched proteomics identifies heat shock cognate 71 protein as a host factor supporting chikungunya virus replication in macrophages

Scientific Reports

Thailand-affiliated authors
Nattaya Kamchompoo · Songkran Thongon · Artittaya Athipanyasilp · Tipparat Thiangtrongjit · Kawin Chantima · Onrapak Reamtong · Kobporn Boonnak
Institutions
Siriraj Hospital · Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
77IMPACT SIGNAL
Clinical Medicine

Multidisciplinary providers’ perspectives on timely predialysis arteriovenous access preparation: An exploratory mixed-methods study in upper Northern Thailand

PLoS ONE

Thailand-affiliated authors
Amaraporn Rerkasem · Kochaphan Phirom · Pak Thaichana · Prit Kusirisin · Puntapong Taruangsri · Suwinai Saengyo · Sasinat Pongtam · Wanicha Pungchompoo · Kittipan Rerkasem
Institutions
Chiang Mai University · Nakornping Hospital · Maharaj Nakorn Chiang Mai Hospital
77IMPACT SIGNAL
Clinical Medicine

Lung Function-Based Assessment of Small Airway Dysfunction in Chronic Respiratory Diseases

Biology

Thailand-affiliated authors
Chalerm Liwsrisakun · Athavudh Deesomchok · Chaicharn Pothirat · Warawut Chaiwong
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Baseline characteristics and practice patterns in geriatric vs. non-geriatric hemodialysis patients: initial results from a Thai nationwide multicenter prospective cohort (Thai-HDcohort)

Renal Failure

Thailand-affiliated authors
Wanjak Pongsittisak · Jeerath Phannajit · Wonngarm Kittanamongkolchai · Theerasak Tangwonglert · Thawee Chanchairujira · Kraiwiporn Kiattisunthorn · Kornchanok Vareesangthip · Bongkod Surattichaiyakul · Arkom Nongnuch · Surachet Vongsanim · Pantipa Tonsawan · Pornpen Sangthawan · Siribha Changsirikulchai · Phanupong Phutrakool · Peerapat Thanapongsatorn · Pichaya Tantiyavarong · Talerngsak Kanjanabuch · Khajohn Tiranathanagul · Suchai Sritippayawan · Suree Yoowannakul · Vuddhidej Ophascharoensuk · Paweena Susantitaphong
Institutions
Navamindradhiraj University · Chulalongkorn University · King Chulalongkorn Memorial Hospital · Phramongkutklao Hospital · Siriraj Hospital · Rajamangala Institute of kidney disease · Mahidol University · Ramathibodi Hospital · Chiang Mai University · Khon Kaen University · Prince of Songkla University · Srinakharinwirot University · Thammasat University · Bhumibol Adulyadej Hospital
77IMPACT SIGNAL
Clinical Medicine

Elevated Lipoprotein(a) in Asian Populations and its Implications for Cardiovascular Disease

JACC Asia

Thailand-affiliated authors
Rungroj Krittayaphong
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Multidisciplinary

Multiobjective V H H discovery through integrated high-throughput screening and AlphaFold3-guided structural prioritization

Science Advances

Thailand-affiliated authors
Suthimon Thumtecho
Institutions
King Chulalongkorn Memorial Hospital
77IMPACT SIGNAL
Environmental Engineering

Growth, Antioxidant, and Physiological Responses Associated with Tuber Yield in Cassava Under Irrigation and Late-Season Drought Conditions in a Tropical Savanna Climate

Plants

Thailand-affiliated authors
Supranee Santanoo · Passamon Ittipong · Nimitr Vorasoot · Sanun Jogloy · Kochaphan Vongcharoen · Piyada Theerakulpisut · Poramate Banterng
Institutions
Khon Kaen University · Kalasin University
77IMPACT SIGNAL
Clinical Medicine

Reduced Plasma Cardiac Myosin-Binding Protein-C Concentrations in Cats with Hypertrophic Cardiomyopathy: Evidence from Chronic, Treated Disease

Animals

Thailand-affiliated authors
Nutcha Tanakwang · Natcha Sakunasing · Sarawut Kumphune · Raktham Mektrirat · Kannika Na Lampang · Chavalit Boonyapakorn · Wanpitak Pongkan
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Computational Investigation of S781F Mutation-Induced Remodeling of the Staphylococcal Nuclease Domain-Containing Protein 1–Argonaute 2 Interface

International Journal of Molecular Sciences

Thailand-affiliated authors
Jittasak Khowsathit · Manu Deeudom · Warinda Prommachote · Bishant Pokharel · Pimpisid Koonyosying · Somdet Srichairatanakool
Institutions
Chiang Mai University · Walailak University
77IMPACT SIGNAL
Clinical Medicine

Parental Experiences of Anesthesia Consent for Children with Retinoblastoma Undergoing Ophthalmologic Examinations under Anesthesia: A Qualitative Interview Study

Journal of Health Science and Medical Research

Thailand-affiliated authors
Sutida Boonkamjad · Kholid Karunan · Darunee Sripadungkul · Kotchakron Palachewa · Laksanawadee Chairatana
Institutions
Khon Kaen University · Boromarajonani College of Nursing
77IMPACT SIGNAL
Clinical Medicine

Revisiting Asymptomatic Pulmonary Tuberculosis with Cavitary Lesion Detected During Routine Chest Radiography in a Healthcare Worker: A Case in Point

THE BANGKOK MEDICAL JOURNAL

Thailand-affiliated authors
Charnarong Khajornsuwan · Narongpon Dumavibhat · Supakorn Chansaengpetch · Wipaporn Homchan · Nisa Muangman · Krittachat Butnian · Benjawan Inkham · Tirathat Virojskulchai · Thirajit Boonsaen · Pennapa Kaweewongprasert · Sitthiphon Bunman · Sichon Luerithiphong
Institutions
Chulalongkorn University · Siriraj Hospital · Mahidol University · Thammasat University
77IMPACT SIGNAL
Clinical Medicine

Effect of derotation boot versus skin traction on pain in patients with intertrochanteric fractures a randomized controlled trial

Scientific Reports

Thailand-affiliated authors
Sanzhar Artykbay · Saran Tantavisut · Chavarin Amarase · Pariwat Taweekitikul · Techit Leelasestaporn · Supacheep Viriyakorkitkul
Institutions
Chulalongkorn University · Queen Savang Vadhana Memorial Hospital · King Mongkut Memorial Hospital
77IMPACT SIGNAL
Environmental Engineering

Extraction and Reuse of Disperse Dyes from Polyethylene Terephthalate (PET) Fabric in a Subsequent Dyeing Process

Textiles

Thailand-affiliated authors
Jantip Setthayanond · Potjanart Suwanruji · Piyaporn Kampeerapappun · Thitinun Monhaphol Karpkird · Porntip Tooptompong
Institutions
Kasetsart University · Rajamangala University of Technology Krungthep
77IMPACT SIGNAL
Energy and Materials

Fe-Doped TiO2/Hard Carbon-Coated PLA 3D-Printed Structures for Synergistic Adsorption–Photocatalytic Removal of Methylene Blue and Tetracycline in Water

Catalysts

Thailand-affiliated authors
Oratai Jongprateep · Pohnpairin Saengkla · Chanakan Permmit · Tyme Hetrakul · Parichart CHAUM · Benjaporn Inseemeesak · Angsuthorn Ngamprasit · Kulanit Lanamkham · Natthaphong Thanawatchaimongkol · Jittikorn Sakul-ala · Jirayu Kongtip · Ratchatee Techapiesancharoenkij · Gasidit Panomsuwan
Institutions
Kasetsart University · Bangkok University
77IMPACT SIGNAL
Clinical Medicine

Adjunctive Cold Atmospheric Plasma Therapy for Tracheostomy Wound Healing in Critically Ill Patients: A Pilot Randomised Controlled Trial

International Wound Journal

Thailand-affiliated authors
Lalita Jaingim · Kanlayanee Sittiwat · Kotchawan Nongyam · Konlawij Trongtrakul
Institutions
Chiang Mai University · Maharaj Nakorn Chiang Mai Hospital
77IMPACT SIGNAL
Clinical Medicine

Evaluating the diagnostic value of shear wave elastography in early systemic sclerosis: a case-control study

Scientific Reports

Thailand-affiliated authors
Punthip Thammaroj · Sudarat Hongchokthavee · Chawiporn Muktabhant · Chingching Foocharoen · Wiraphong Sucharit
Institutions
Khon Kaen University
77IMPACT SIGNAL
Clinical Medicine

PAH genotypes and their impact on sapropterin responsiveness in Thai patients with phenylalanine hydroxylase deficiency

˜The œItalian Journal of Pediatrics/Italian journal of pediatrics

Thailand-affiliated authors
Dhachdanai Dhachpramuk · N. Densupsoontorn · Napat Sittanomai · Khunton Wichajarn · Thipwimol Tim‐Aroon · Duangrurdee Wattanasirichaigoon · Lukana Ngiwsara · Somporn Liammongkolkul · Hathaichanok Rukprayoon · Sudarat Sirisakpanit · Souwaluck Ratanamalaya · Nithiwat Vatanavicharn
Institutions
Siriraj Hospital · Mahidol University · Khon Kaen University · Ramathibodi Hospital · Chulabhorn Research Institute
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link