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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
Geospatial Agriculture and Environment89IMPACT SIGNAL
Regional model-validation evidence

GEDI–Sentinel Model Maps Northeast Thai Rubber at 82.63% Accuracy but Struggles With Young Plantations

This study mapped 2024 rubber distribution and age structure across Northeast Thailand using Random Forest in Google Earth Engine, combining Sentinel-1, Sentinel-2, vegetation indices, and a GEDI-trained canopy-height model. Three-class rubber mapping reached 82.63% overall accuracy and about 0.84 F1; three-group age classification reached 83.39%. Plantations older than seven years dominated and were classified more reliably than young stands. The output is a regional monitoring baseline, not an error-free parcel-level decision map.

Thai researchersSavittri Ratanopad Suwanlee · Muhammad Hanif · Surasak Keawsomsee · Kemin Kasa · Narissara Nuthammachot · Sarawut Ninsawat · Jantima Polpinij · Jaturong Som-Ard
Medical Education and Serious-Illness Care89IMPACT SIGNAL
Longitudinal training evidence

Advance-Care-Planning Training Raised Residents’ Knowledge From 7.74 to 8.65, but Had No Control Group

This mixed-methods evaluation tested an Advance Care Planning programme combining role-play, personal-value reflection, and two Circle of Learning sessions with an entire cohort of 50 first-year internal-medicine residents. Longitudinal analysis used 34 complete cases through 15 months, and 10 residents were interviewed. Knowledge rose from 7.74 to 8.65 out of 9, alongside several attitude and confidence improvements. Interviewees said role-play bridged theory and practice but identified a need for ongoing workplace support. The evidence concerns learner readiness, not observed conversation quality or patient outcomes.

Thai researchersThagoon Kanjanopas · Smuch Siramongkholkarn · Wanna Jarusomboon · Ekkapop Sittiwantana · Arisa Phochaisarn · Saipin Hathirat · Saran Thanapluetiwong
Public Health and Migrant Health92IMPACT SIGNAL
Evidence of global relevance

Migrant TB Patients Chose Months-Long Sanatorium Care to Pursue Cure Amid Cost, Transport, and Documentation Barriers

This multi-perspective qualitative study at the SMRU tuberculosis sanatorium in Mae Ramat, Tak Province, examined why migrants choose long residential treatment. It included 37 unique patients—33 who chose the sanatorium and four who chose community DOTS—plus five health workers. Three themes organized the findings: desire for cure, barriers to diagnosis and treatment, and community and organizational support.

Thai researchersJindaporn Wirachonphaophong · Hai Ti Ti · Nay Kaw Htoo · Kanjana Winyoorat · Cha Ba · San Soe · Suphak Nosten · Htet Ko Ko Aung · Sein Sein Thi · Francois Nosten
Public Health and Health Systems92IMPACT SIGNAL
Qualitative evidence for service design

Patients in South Ethiopia Know How to Manage Diabetes, but Drug Shortages and Costs Undercut Self-Care

This qualitative study examined diabetes self-care in three South Ethiopian hospital clinics. Its 21 participants comprised 12 adults with type 2 diabetes and nine healthcare providers. Patients described medication, diet, physical activity, foot care, and glucose monitoring as daily work negotiated against financial pressure, drug shortages, beliefs, food costs, limited support, and health-system constraints. Patients tended to foreground structural barriers, whereas providers placed more emphasis on knowledge and forgetting advice. Continued counselling, reliable medicines, and peer support emerged as priorities, but these are interview-derived design directions rather than tested interventions.

Thai researchersTemesgen Anjulo Ageru · Cua Ngoc Le · Apichai Wattanapisit · Charuai Suwanbamrung
International Journal of Qualitative Studies on Health and Well-beingRead analysis →
Forest Policy and Bioeconomy92IMPACT SIGNAL
Evidence of global relevance

Perspectives on the forest bioeconomy: insights of stakeholders from cases in Central Europe and the Mekong region

This comparative study examines how 336 purposively recruited respondents in Czechia, Slovakia, Thailand, Laos and Vietnam understand and assess the forest bioeconomy. Respondents generally reported stronger familiarity with sustainable forest management and the circular economy than with the bioeconomy itself. Perceptions also varied across country cases, particularly within the Mekong region. A binary logistic regression identified associations between high perceived implementation and country, age, education, understanding of policy aims, support for implementation and positive assessments of forest-industry implementation. These findings describe perceptions within the recruited sample rather than national populations, and the reported associations should not be interpreted as causal effects.

Thai researchersNopparat Kaakkurivaara · Alice Sharp · Prasit Wangpakapattanawong
One Health and Zoonotic-Disease Prevention92IMPACT SIGNAL
Formative evidence for One Health intervention design

Zoonotic Risk in Rural Nan Is Not Just Behavioural: Water Scarcity, Forest Change, and Food Systems Connect Five Interfaces

Researchers examined everyday practices and conditions that could enable cross-species transmission in four rural villages in Nan Province, organising findings into five interfaces: human–animal, human–environment, human-human, animal–animal, and animal–environment. The picture is not simply one of deficient knowledge. Animal contact, butchering and food preparation, water scarcity and contamination, waste, forest change, intensified agriculture, mixed-species proximity, and multilingual communication operate as a system. Community leaders and village health volunteers were viewed as trusted messengers. The study therefore recommends education that combines knowledge, skills, practical tools, and recognition of structural limits, but it neither completed nor evaluated the final intervention.

Thai researchersMonchai Phongsiri · Simaphon Tomklang · Theerayuth Labooth · Thanapat Chaibut · Pongsakon Jaruton · Kotthamon Chanprathad · Sarutaya Suphawatthanaphan · Hans Overgaard · Patcharin Lapanun
Circular Bioeconomy and Seafood Technology92IMPACT SIGNAL
Comprehensive narrative-review evidence

Crustacean By-Products Hold High-Value Compounds, but ‘Green’ Extraction Still Lacks LCA and Industrial Proof

This review compares conventional acid–alkali and solvent extraction with supercritical fluids, enzymatic hydrolysis, pulsed electric fields, ultrasound, cold plasma, microwave, high-pressure processing, and deep eutectic solvents for recovering bioactives from crustacean by-products. No technology is universally optimal: conventional methods retain advantages in simplicity and maturity, while emerging methods may reduce chemicals or better preserve product quality but face equipment, cost, energy, reproducibility, and pilot-scale constraints. The paper is therefore a map of options and evidence gaps, not proof that one technology is the ‘most sustainable.’

Thai researchersAkanksha R. Gautam · Soottawat Benjakul · Rattikarn Boonchoosri · Nilesh Nirmal · Avtar Singh
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
77IMPACT SIGNAL
Clinical Medicine

FACTORS ASSOCIATED WITH HOSPITAL ARRIVAL TIME IN ISCHEMIC STROKE PATIENTS AT BUDDHASOTHORN HOSPITAL: AN AMBISPECTIVE OBSERVATIONAL COHORT STUDY

Journal of Southeast Asian Medical Research

Thailand-affiliated authors
Sirinapa Saneemanomai · Phatchapong Rurgring · Thinnapat Ninthasuk · Juthatip Rooyoo · Jidaporn Burenoi · Neera Krasaesoontorn · Benjawan Saengluan · Nunnaphat Khantiviriyapanich · Kanokporne Nakboon
Institutions
Rajabhat Rajanagarindra University · Thammasat University Hospital
77IMPACT SIGNAL
Clinical Medicine

Metabolic and Inflammatory Risk Stratification in Resected Cholangiocarcinoma: A Retrospective Exploratory Analysis

Medical Sciences

Thailand-affiliated authors
Piya Prajumwongs · Attapol Titapun · Vasin Thanasukarn · Apiwat Jareanrat · Natcha Khuntikeo · Nisana Namwat · Poramate Klanrit · Arporn Wangwiwatsin · Jarin Chindaprasirt · Prakasit Sa-Ngiamwibool · Nattha Muangritdech · Sittiruk Roytrakul · Watcharin Loilome
Institutions
Khon Kaen University · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
77IMPACT SIGNAL
Clinical Medicine

Soluble C-type lectin LvLectin1 mediates recognition and agglutination of Ecytonucleospora hepatopenaei spores in Pacific white shrimp Litopenaeus vannamei

Aquaculture Reports

Thailand-affiliated authors
Warumporn Yingsunthonwattana · Kanokporn Bunyanam · Wisarut Junprung · Prakob Saman · Anchalee Tassanakajon
Institutions
Chulalongkorn University · Charoenkrung Pracharak Hospital
77IMPACT SIGNAL
Clinical Medicine

Three Decades of Outcomes in Pediatric Inborn Errors of Immunity in a Middle-Income Setting: Survival by IUIS Class and the Role of HSCT

Journal of Clinical Immunology

Thailand-affiliated authors
Chanunchida Watcharaporn · Usanarat Anurathapan · Suradej Hongeng · Samart Pakakasama · Wasu Kamchaisatian · Watcharoot Kanchongkittiphon · Wiparat Manuyakorn
Institutions
Mahidol University · Ramathibodi Hospital
77IMPACT SIGNAL
Clinical Medicine

Cooking-Induced Molecular Transformations in Foods: Matrix-Dependent Effects on Bioaccessibility, Metabolism, and Health

Food Reviews International

Thailand-affiliated authors
Muhammad Waqar
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

A rapid hybridization-free LAMP–LFB assay for the clinical detection of Neisseria gonorrhoeae in urine specimens

Scientific Reports

Thailand-affiliated authors
Jutturong Ckumdee · Somchai Santiwatanakul · Rossaphorn Kittiyaowamarn · Thongchai Kaewphinit
Institutions
Navamindradhiraj University · Vajira Hospital · Srinakharinwirot University · Ministry of Public Health
77IMPACT SIGNAL
Clinical Medicine

Effects of Ramadan Fasting on Intradialytic Hypoglycemia and Clinical Outcomes in Patients with Diabetes on Maintenance Hemodialysis: A Multicenter Prospective Cohort Study in Southern Thailand

Medical Sciences

Thailand-affiliated authors
Jayanton Patumanond · Moragot Chatatikun · Atthaphong Phongphithakchai
Institutions
Naresuan University · Walailak University · Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Diagnostic Performance of Six Tests for Helicobacter pylori Infection in Peptic Ulcer Bleeding: A Prospective Head-to-Head Comparison

Clinical and Translational Gastroenterology

Thailand-affiliated authors
Tanawat Geeratragool · Thanapat Atthakitmongkol · Supathep Tansirichaiya · Pubet Weeranawin · Somchai Leelakusolvong · Monthira Maneerattanaporn
Institutions
Siriraj Hospital
77IMPACT SIGNAL
Clinical Medicine

Epidemiology and mortality rate of thyroid storm in Thailand: Analysis using a national in-patient database

PLoS ONE

Thailand-affiliated authors
Jin Sothornwit · Suranut Charoensri · Dueanchonnee Sribenjalak · Chatlert Pongchaiyakul
Institutions
Khon Kaen University
77IMPACT SIGNAL
Global Public Health

Effectiveness of a hybrid practice-based training program for community-based elderly caregivers in Chiang Rai during the COVID-19 pandemic

Journal of Public Health and Development

Thailand-affiliated authors
Ananya Eusawat · Watcharapong Ruankham · Rawipat Pullap · Piyaporn Tamesak · Nattra Somkamlang
Institutions
Chiang Rai Rajabhat University
77IMPACT SIGNAL
Clinical Medicine

Gelatin Hydrolysate from Bigeye Snapper (Priacanthus tayenus) Skin Attenuates the Progression of Diabetic Nephropathy in Rats by Modulating Oxidative Stress, Inflammatory Responses, and Endoplasmic Reticulum Stress Signaling Pathways

International Journal of Molecular Sciences

Thailand-affiliated authors
Krit Jaikumkao · Khin Thandar Htun · Nattavadee Pengrattanachot · Prempree Sutthasupha · Sasivimon Promsan · Napatsorn Montha · Onanong Jaruan · Rarin Suriyalungka · Phassaraporn Khadtha · Sompong Sriburee · S. Kothan · Sutee Wangtueai · Anusorn Lungkaphin
Institutions
Chiang Mai University · Kasetsart University · University of Phayao
77IMPACT SIGNAL
Energy and Materials

Unlocking High-Valent Chalcogen Redox with Halide-Rich Electrolytes for High-Energy Lithium Batteries

Nature Communications

Thailand-affiliated authors
Jiaqian Qin
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Prediction model for survival outcome in patients with acute myeloid leukemia: a multicenter prospective cohort study from Thai Acute Leukemia Working Group

Frontiers in Oncology

Thailand-affiliated authors
Pirun Saelue · Jakrawadee Julamanee · Adisak Tantiworawit · Thanawat Rattanathammethee · Weerapat Owattanapanich · Smith Kungwankiattichai · Chantiya Chanswangphuwana · Chantana Polprasert · Wasithep Limvorapitak · Supawee Saengboon · Kannadit Prayongratana · Chantrapa Sriswasdi · Pimjai Niparuck · Teeraya Puavilai · Chajchawan Nakhakes · Chinadol Wanitpongpun
Institutions
Prince of Songkla University · Chiang Mai University · Siriraj Hospital · Chulalongkorn University · King Chulalongkorn Memorial Hospital · Thammasat University · Phramongkutklao Hospital · Ramathibodi Hospital · Rajavithi Hospital · Khon Kaen University
77IMPACT SIGNAL
Clinical Medicine

Immune response and durability of human papillomavirus antibodies in vaccinated adolescents after hematopoietic stem cell transplantation: a pilot study

BMC Infectious Diseases

Thailand-affiliated authors
Benjaporn Wangviboonchai · Phuwakrit Nithirungruang · Usanarat Anurathapan · Samart Pakakasama · Suradej Hongeng · Chompunuch Klinmalai · Nopporn Apiwattanakul
Institutions
Mahidol University · Ramathibodi Hospital
77IMPACT SIGNAL
Environmental Engineering

Culturable mycota from Karst caves in Yunnan Province, China

IMA Fungus

Thailand-affiliated authors
Xiang-Fu Liu · K. W. Thilini Chethana · Lu Li · Kevin D. Hyde · Wenhua Lu · Rui-Fang Xu · Xue-Mei Chen · Xian Zhang · Xing-Juan Xiao · Tian‐Ye Du · Nakarin Suwannarach · Jaturong Kumla
Institutions
Mae Fah Luang University · Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Association of Vitamin D Intake, VDR Levels, and Relevant Gene Polymorphisms in Early-Stage Thai Colorectal Cancer Patients Following Vitamin D3 Supplementation

Medical Sciences

Thailand-affiliated authors
Natthaporn Kuendee · Aunchana Rodrungnok · Kamphon Intharanut · Alisa Naladta · Oytip Nathalang · Sakda Daduang · Sophida Sukprasert
Institutions
Rajamangala University of Technology Tawan-ok · Thammasat University · Khon Kaen University
77IMPACT SIGNAL
Clinical Medicine

Expanding the Diversity of Penicillium in Thailand: New Records and Habitat—Substrate Associations

Phytotaxa

Thailand-affiliated authors
SUBASINGHA A.D. THAKSHILA · Chitrabhanu S. Bhunjun
Institutions
Mae Fah Luang University
77IMPACT SIGNAL
Global Public Health

HIV disclosure and stigma among couples in Muslim communities in Indonesia: a qualitative study

BMC Public Health

Thailand-affiliated authors
Eka Sari Ridwan · Sarunya Benjakul · Mondha Kengganpanich · Chanuantong Tanasugarn
Institutions
Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Ingredient characterization and preclinical evaluation of a standardized crude hydrolyzed yeast β-glucan preparation (crude-HBGs) derived from insoluble yeast β-glucans: Cerebrovascular outcomes in HFD/STZ-induced diabetic rats

Food Bioscience

Thailand-affiliated authors
Wipapan Khimmaktong · Nissara Lorthong · Abdulhakam Dumidae · Pannawich Sukprasirt · Rapepun Wititsuwannakul · Aratee Aroonkesorn · Thanawat Pitakpornpreecha
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

A study protocol of the additional human albumin during resuscitation in patients with surgical septic shock: A randomized controlled trial (the ALBumin Use in Surgical septic shock, ALBUS study)

Clinical Critical Care

Thailand-affiliated authors
Nattachai Hemtanon · Nuanprae Kitisin · Thassayu Yuyen · Nattaya Raykateeraroj · Patipan Toomtong · Prasert Sawasdiwipachai · Onuma Chaiwat · Annop Piriyapatsom · Karuna Wongtangman · Nonthida Rojanapithayakorn · Suchanun Lao-amornphunkul · Thirada Srinil · Napat Thikom · Chayanan Thanakiattiwibun · Paramet Bumroongsawat · Ornsuma Tansritrang · Julalak Sobha
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Blood metabolomes distinguish malnutrition and reflect treatment response in adult thalassemia patients: a randomized controlled trial

Scientific Reports

Thailand-affiliated authors
Chanisa Thonusin · Rattana Weerasathain · Pokpong Piriyakhuntorn · Supawan Buranapin · Thanawat Rattanathammethee · Sasinee Hantrakool · Chatree Chai‐Adisaksopha · Ekarat Rattarittamrong · Lalita Norasetthada · Nonthakorn Hantrakun · Teerachat Punnachet · Nuttanun Wongsarikan · Wichwara Nawara · Nipon Chattipakorn · Adisak Tantiworawit · Siriporn C. Chattipakorn
Institutions
Chiang Mai University · The Royal College Of Anesthesiologists Of Thailand
77IMPACT SIGNAL
Multidisciplinary

Knotless barbed suture is associated with fewer short-term cesarean scar defects compared with conventional suture in a randomized controlled trial

Scientific Reports

Thailand-affiliated authors
Supapun Wattanacharoen · Chada Burapasikarin · Wirun Thongchumnum · Kittisak Sawanyawisuth
Institutions
Vachira Phuket Hospital · Khon Kaen University
77IMPACT SIGNAL
Clinical Medicine

Neutropenia in adult patients with thalassemia receiving deferiprone: a 10-year experience from a large thalassemia cohort

Blood Research

Thailand-affiliated authors
Ploylarp Lertvipapath · Weerapat Owatanapanich · Waratchaya Uawattanasakul · Smith Kungwankiattichai
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Effects of Adding BreatheMAX-Assisted Deep Breathing to Home-Based Spot Marching on Maximal Voluntary Ventilation and Peak Expiratory Flow in Young Adults with Overweight or Obesity: A Randomized Controlled Trial

International Journal of Environmental Research and Public Health

Thailand-affiliated authors
Sujittra Kluayhomthong · Nontanat Sathaporn · Parkpoom Pipatbanjong · Umaporn Panpang · Kanyanat Kanka · Noppasorn Promman · Phanpan Inthajark · Sasit Sutawong · Pakhin Thamwiwat · Suntichai Prachumkhong · Vitsarut Buttagat
Institutions
Mae Fah Luang University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link