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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
Public Health74IMPACT SIGNAL
Evidence of global relevance

Severe Pregnancy-Associated Acute Kidney Injury and Maternal Vulnerability

Electronic records covering 4,094,111 US pregnancies showed severe pregnancy-associated acute kidney injury rising from 9.0 to 27.6 per 10,000 pregnancies between 2012-2013 and the COVID-19 era. Pre-existing cardiometabolic vulnerability was associated with risk, but observational data cannot separate infection, access, testing, and secular trends.

Thai researchersNattachai Srisawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Integrative hematological and transcriptomic analysis reveals monocyte alterations and molecular signatures of inflammatory-coagulation crosstalk in long COVID

A comparison of 21 people with long COVID and 24 asymptomatic controls found lower white-cell, monocyte, and platelet counts and longer APTT. Integrated with a separate public transcriptomic dataset, the findings support a proposed inflammation-coagulation model, but the small and non-identical datasets cannot establish mechanism.

Thai researchersParin Kamseng · Namngern Chantaramanee · Rittikorn Sompan · Sarayot Rareongjai
Public Health74IMPACT SIGNAL
Evidence of global relevance

Toxicological Assessment of Oligofructans Derived from Raw Sugar Fermentation by Bacillus subtilis TISTR 001 and Their Modulatory Effects on Rat Gut Microbiota

Thai researchers evaluated oligofructans produced from raw sugar using Bacillus subtilis TISTR 001. Rats showed no treatment-related mortality or toxicity at doses up to 2,000 mg/kg/day for 90 days, alongside reported shifts in gut microbial taxa. These are preclinical animal findings and do not establish human safety or benefit.

Thai researchersSirinya Taya · Boontiwa Ninchan · Sonthaya Umsumarng · Jutamat Klinsoda · Rawiwan Wongpoomchai · Charatda Punvittayagul
Environment and Engineering74IMPACT SIGNAL
Evidence of global relevance

A Multi-Frequency SAR Framework for Methane Emission Estimation in Thai Rice Paddies

A GISTDA-led framework combines Sentinel-1 and ALOS-2 radar with IPCC accounting to detect crop timing, classify water regimes, and estimate methane from irrigated rice in Thailand's central plain. Mean absolute error was 18.5 kg CH4/ha, but structural uncertainty in the IPCC Tier 1 emission factor exceeded all algorithmic errors combined.

Thai researchersNuntikorn Kitratporn · Kanjana Koedkurang · Panu Nueangjamnong · Kittiphop Simachokchai · Chompunut Chayawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Predictors of Early Recurrence and Survival Outcomes Following Curative Resection for Colorectal Liver Metastases and the Role of Salvage Surgery: A Retrospective Cohort Study

In a retrospective cohort of 109 patients undergoing liver resection for colorectal liver metastases, high tumor burden, major intraoperative blood loss, T3/T4 primary disease, and RAS mutation were associated with early recurrence. Selected patients undergoing salvage re-hepatectomy had favorable long-term survival, but small subgroups and strong selection bias prevent causal conclusions.

Thai researchersPipit Burasakarn · Nisanat Thongkua · Vachiraluck Chalokool · Anuparp Thienhiran · Sermsak Hongjinda · Pusit Fuengfoo
Mental Health74IMPACT SIGNAL
Evidence of global relevance

The Study of Efficacy and Safety of a Modified Chaihu Shugan San Formula in the Treatment of Insomnia Associated with Stress: A Pilot Clinical Evaluation

A 30-participant pre-post pilot reported lower sleep-quality and stress scores after four weeks of twice-daily modified Chaihu Shugan San, without clear liver or renal safety signals. Without randomization, a control group, or placebo, the study cannot separate the formula's effect from placebo, attention, or change over time.

Thai researchersPorwarut Srihara · Cao ZuoJun · Somratchanee Srifar · Mattanapat Phraecharoen
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Benefits of three consecutive sputum inductions using nebulized racemic salbutamol versus hypertonic saline in smear-negative or sputum-scarce pulmonary tuberculosis patients: a prospective randomized, double-blind study

In a randomized double-blind trial of 345 adults with suspected smear-negative or sputum-scarce pulmonary tuberculosis, three consecutive daily inductions with nebulized racemic salbutamol produced a higher combined smear-or-culture yield and fewer adverse events than 3% hypertonic saline. The single-center study evaluates specimen collection for diagnosis, not tuberculosis treatment outcomes.

Thai researchersWarangkana Keeratichananont · Suriya Keeratichananont · Natthaphon Ubonsutvanich · Jirachaya Chaisurote
Thai Fruit and Diabetic Retinal Mechanisms74IMPACT SIGNAL
Evidence of global relevance

ANTIOXIDANT AND ANTI-APOPTOTIC ACTIVITIES OF MAKIANG FRUIT EXTRACT IN ARPE-19 CELLS EXPOSED TO GLUCOSE-INDUCED CELLULAR DAMAGE

A 95% ethanol makiang-fruit extract showed antioxidant activity and, when co-administered in 30 mM glucose-exposed ARPE-19 cells, the highest 200 microgram/mL dose increased viability by 15.4%, reduced ROS by 37.8%, and lowered caspase-9 and -3 activities.

Thai researchersNuntaporn Chanpurk · Kemika Praengam · Angkalsiri Deeaum · Pasitta Panritdum · Monruedee Sukprasansap · Chawanphat Muangnoi
Green-Tea Compounds and Diabetic Kidney Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Epigallocatechin-3-gallate, l-theanine and theophylline abolish high-glucose-induced renal cell senescence and subsequent epithelial-mesenchymal transition and fibroblast activation via SIRT1/PGC-1α axis: Implications for diabetic kidney disease

High glucose induced senescence in proximal tubular cells, whose SASP-conditioned medium then triggered epithelial-mesenchymal transition in distal tubular cells and fibroblast activation. EGCG, L-theanine, and theophylline suppressed these effects while restoring SIRT1/PGC-1alpha signaling.

Thai researchersRattiyaporn Kanlaya · Sunisa Yoodee · Kanokwan Nonthawong · Chonicha Subkod · Supanan Nanthawuttiphan · Visith Thongboonkerd
Curcumin and Breast-Tumor Immunity74IMPACT SIGNAL
Evidence of global relevance

Curcumin Attenuates Breast Cancer Cell-induced Inflammasome Activation via the NOD-like receptor protein 3/Caspase-1/Interleukin-1β Axis

Breast-cancer-cell conditioned medium drove THP-1-derived macrophages toward a pro-inflammatory tumor-associated phenotype with higher IL-1beta, NLRP3, and caspase-1. Curcumin pretreatment reduced IL-1beta secretion, NLRP3 protein, and IL1B/CASP1 transcripts.

Thai researchersKhwandow Kunchana · Wattanased Jarisarapurin · Suvara K. Wattanapitayakul
Encephalitis Viruses and Cell-Death Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Inhibition of calpain-mediated BAX cleavage attenuates Japanese encephalitis virus-induced apoptosis in SH-SY5Y neuroblastoma cells

In SH-SY5Y cells, Japanese encephalitis virus activated calpain to cleave BAX into p18 BAX, which moved to mitochondria and triggered cytochrome c, caspase-3, PARP cleavage, and apoptosis. The calpain inhibitor calpeptin attenuated these signals and improved cell viability.

Thai researchersKuntida Kitidee · Arisara Samutpong · Nattaporn Pakpian · Montri Yasawong · Prapimpun Wongchitrat
Occupational Lung Health and AI Screening74IMPACT SIGNAL
Evidence of global relevance

Artificial neural network modelling using complete blood count for the early detection of black lung disease among Indonesian coal miner: A retrospective longitudinal study

Annual health data from 807 Indonesian coal miners followed from 2013-2021 showed 13.9% cumulative black-lung incidence. A complete-blood-count neural network and Cox model both identified eosinophils and monocytes as influential predictors.

Thai researchersKurnia Ardiansyah Akbar · Kraiwuth Kallawicha · Pallop Siewchaisakul
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
77IMPACT SIGNAL
Clinical Medicine

Whole-Genome Sequencing Reveals Virulence and Antimicrobial Resistance Determinants of Lactococcus garvieae Causing Lactococcosis in Cage-Cultured Nile Tilapia (Oreochromis niloticus) in Thailand

International Journal of Molecular Sciences

Thailand-affiliated authors
Putita Chokmangmeepisarn · Yosapon Adisornprasert · Pakapon Meachasompop · Benchawan Kumwan · Pimrawee Chaemlek · Prapansak Srisapoome · Kednapat Sriphairoj · Sittichai Hatachote · Niyada Umputhorn · Chonthicha Choppradit · Pichasit Sangmek · Channarong Rodkhum · Anurak Uchuwittayakul
Institutions
Kasetsart University · Sakon Nakhon Rajabhat University · Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Novel prediabetes subtypes and genetic variants predict differential risk of progression to type 2 diabetes: a data-driven cohort analysis

BMC Endocrine Disorders

Thailand-affiliated authors
Apinya Surawit · Phongthana Pasookhush · Sureeporn Pumeiam · Pichanun Mongkolsucharitkul · Sophida Suta · Bonggochpass Pinsawas · Suphawan Ophakas · Nutchavadee Vorasan · Parit Voharnsuchon · Korapat Mayurasakorn
Institutions
Siriraj Hospital
77IMPACT SIGNAL
Clinical Medicine

Left ventricular stroke volume index predicts outcomes in asymptomatic chronic severe primary mitral regurgitation

Journal of Cardiovascular Imaging

Thailand-affiliated authors
Porntera Sethalao · Nithima Ratanasit · Decho Jakrapanichakul · Sasima Tongsai · Sirichai Jamnongprasatporn
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Prevalence, risk factors and outcomes of sepsis-associated acute kidney injury in pediatric patients

BMC Nephrology

Thailand-affiliated authors
Watcharaporn Lertbunyarit · Rattapon Uppala · Pasita Puttiteerachot · Jarin Vaewpanich · Nattachai Anantasit
Institutions
Mahidol University · Ramathibodi Hospital · Khon Kaen University
77IMPACT SIGNAL
Clinical Medicine

Clinical Implications of the AWGS 2025 Sarcopenia Criteria in a Large Cohort of Community-Dwelling Thai Older Adults

Annals of Geriatric Medicine and Research

Thailand-affiliated authors
Natthaphon Ubonsutvanich · Rapas Samalapa · Thanyaporn Hengpongthorn · Chawalya Angsuwatjarakorn · Aisawan Petchlorlian · Bhorn-ake Manasvanich · Sivarat Ratthanasathian · Kearkiat Kearkiat
Institutions
Chulalongkorn University · King Chulalongkorn Memorial Hospital · Thai Red Cross Society · Navamindradhiraj University · Vajira Hospital
77IMPACT SIGNAL
Clinical Medicine

Agentic AI-Driven Cultivation Advisory and Symptom-Level Diagnostic Support in a Controlled Indoor Farming System

AgriEngineering

Thailand-affiliated authors
Jutarut Chaoraingern · Akarat Pattaraanuvong · Kantapon Paraksa · Kantiporn Khunthong · Tirawat Nontiwantok · Arjin Numsomran
Institutions
King Mongkut's Institute of Technology Ladkrabang
77IMPACT SIGNAL
Clinical Medicine

Heme Oxygenase-1 in Bone Remodeling: Molecular Mechanisms and Therapeutic Implications

Biomolecules

Thailand-affiliated authors
Thanawat Pattananandecha · Sutasinee Apichai · Chalermpong Saenjum
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Alterations in Nasal Function Following Total Laryngectomy and Their Clinical Correlates

World Journal of Otorhinolaryngology - Head and Neck Surgery

Thailand-affiliated authors
Kajornpan Sermwittayawong · Paraya Assanasen · Phawin Keskool · Dichapong Kanjanawasee
Institutions
Huachiew Chalermprakiet University · Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Clinical Medicine

Diagnostic accuracy of a clinical score with a rapid diagnostic test for enteric fever in Nepal, Bangladesh and Cambodia

BMC Infectious Diseases

Thailand-affiliated authors
Nicholas P.J. Day · Arjen Dondorp
Institutions
Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
77IMPACT SIGNAL
Clinical Medicine

Shared and Distinct T-Cell Receptor Characteristics of CD4+ and CD8+ Drug-Specific T-Cells In Vitro Generated from Healthy Donors and Hypersensitive Patients

Chemical Research in Toxicology

Thailand-affiliated authors
Kanoot Jaruthamsophon · Jirawat Pratoomwun · Antida Sangiemchoey · Araya Yeunyongviwat · Kanitpong Phabphal · Chonlaphat Sukasem
Institutions
Prince of Songkla University · Huachiew Chalermprakiet University · Mahidol University · Ramathibodi Hospital · Burapha University
77IMPACT SIGNAL
Clinical Medicine

Localization of feline gammaherpesvirus 1 in lymphoid tissues and pulmonary fibrotic lesions of naturally infected cats

Veterinary Pathology

Thailand-affiliated authors
Chutchai Piewbang · Magdalena Novia Devina Putri · Aisyah Nikmatuz Zahro · Panitnan Punyathi · Sitthichok Lacharoje · Somporn Techangamsuwan
Institutions
Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Clinical features associated with autism spectrum disorder diagnosed before 30 months of age: evidence from tertiary care hospitals in Thailand

International Journal of Developmental Disabilities

Thailand-affiliated authors
Anya Laopongsit · Nontiya Homkham · Pimwarat Srikummoon · Kamonrut Koobubpha · Patrinee Traisathit
Institutions
Chiang Rai Rajabhat University · Thammasat University · Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Rapid Gel-Based Recombinase Polymerase Amplification Assay for Detection and Sequence Confirmation of Ehrlichia canis

Animals

Thailand-affiliated authors
Peeravit Sumpavong · Kitjawan Khumtub · Krittanut Kanittakul · Sarawan Kaewmongkol · Gunn Kaewmongkol
Institutions
Kasetsart University
77IMPACT SIGNAL
Clinical Medicine

Synchronous B-lymphoblastic leukemia/lymphoma and subcutaneous panniculitis-like T-cell lymphoma in an 11-year-old pediatric patient

BMC Pediatrics

Thailand-affiliated authors
Phuphinyo Limchantra · Jirat Temsangsukmanee · Suradej Hongeng · Kran Suknuntha
Institutions
Mahidol University · Ramathibodi Hospital
77IMPACT SIGNAL
Clinical Medicine

A Decade of Croup Management: Guideline Adherence, Practice Variation, and Opportunities for Improvement

Children

Thailand-affiliated authors
Jirattikarn Jirawong · Wanaporn Anuntaseree · Kanokpan Ruangnapa · Kantara Saelim · Pharsai Prasertsan
Institutions
Prince of Songkla University
77IMPACT SIGNAL
Clinical Medicine

Cloud-Based Deep Learning for Multi-Class Dermatological Screening: An Empirical Study Using Pretrained CNNs

Sci

Thailand-affiliated authors
Theetach Rabablert · Amonnat Kaewnok · Chitnarong Sirisathitkul · Yaowarat Sirisathitkul
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

Molecular Characteristics and Factors Associated with Antimicrobial Resistance in Campylobacter Isolates from Small-Scale Chicken Farms in Southern Thailand

Antibiotics

Thailand-affiliated authors
Nguyễn Thị Mỹ Nhân · Phitchayapak Wintachai · Thotsapol Thomrongsuwannakij
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

PARP inhibition induces a redox-dependent dormant reservoir vulnerable to disulfiram in high-grade serous ovarian cancer

Biomedicine & Pharmacotherapy

Thailand-affiliated authors
Sutthipun Suriya · Supawan Jamnongsong · Chanettee Jamyuang · Suwanit Therasakvichya · Somponnat Sampattavanich
Institutions
Siriraj Hospital · Mahidol University
77IMPACT SIGNAL
Digital Health

Electroencephalography-Based Emotion Recognition Using Auditory Stimulation for Affective Brain–Computer Interfaces

Sensors

Thailand-affiliated authors
Charoenporn Bouyam · Nannaphat Siribunyaphat · Yunyong Punsawad
Institutions
Walailak University
77IMPACT SIGNAL
Clinical Medicine

KK12, a novel anticancer peptide, induces apoptosis in human lung cancer A549 cells

Scientific Reports

Thailand-affiliated authors
Jantana Yahuafai · Prayumat Onsrisawat · Ratasark Summart · Mariena Ketudat-Cairns · Thippawan Pimchan · Jirawat Yongsawatdigul · Natteewan Udomsil
Institutions
National Cancer Institute of Thailand · Kanchanaburi Rajabhat University · Mahidol University · Suranaree University of Technology
77IMPACT SIGNAL
Clinical Medicine

Limitations of NEWS2 for predicting 48-hour emergency department revisits: a real-world retrospective cohort study

International Journal of Emergency Medicine

Thailand-affiliated authors
Sarunpakorn Permpatdechakul · Theerapon Tangsuwanaruk · Borwon Wittayachamnankul · Pavita Laohakul · Chanon Changratanakorn · Boriboon Chenthanakij
Institutions
Chiang Mai University
77IMPACT SIGNAL
Clinical Medicine

Efficacy of mucoadhesive nanoemulsion-based immersion vaccine against Streptococcus agalactiae and Edwardsiella tarda infections in Nile tilapia (Oreochromis niloticus)

Aquaculture Reports

Thailand-affiliated authors
Benchawan Kumwan · Pakapon Meachasompop · Yosapon Adisornprasert · Jitraporn Phaksopa · Wararut Buncharoen · Patcharapong Thangsunan · Pattanapong Thangsunan · Prapansak Srisapoome · Channarong Rodkhum · Natthapong Paankhao · Anurak Uchuwittayakul
Institutions
Kasetsart University · Chiang Mai University · Chulalongkorn University
77IMPACT SIGNAL
Clinical Medicine

Dietary Application of Synergistically Degraded Low-Molecular-Weight Chitosan to Promote Health and Antioxidant Responses in Pacific White Shrimp (Litopenaeus vannamei)

Antioxidants

Thailand-affiliated authors
Natthapong Paankhao · Wararut Buncharoen · Benchawan Kumwan · Pakapon Meachasompop · Yosapon Adisornprasert · Chonlatat Rajitdumrong · Pimrawee Chaemlek · Prapansak Srisapoome · Passakorn Kingwascharapong · Anurak Uchuwittayakul
Institutions
Kasetsart University · Chiang Mai University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link