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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
Public Health74IMPACT SIGNAL
Evidence of global relevance

Severe Pregnancy-Associated Acute Kidney Injury and Maternal Vulnerability

Electronic records covering 4,094,111 US pregnancies showed severe pregnancy-associated acute kidney injury rising from 9.0 to 27.6 per 10,000 pregnancies between 2012-2013 and the COVID-19 era. Pre-existing cardiometabolic vulnerability was associated with risk, but observational data cannot separate infection, access, testing, and secular trends.

Thai researchersNattachai Srisawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Integrative hematological and transcriptomic analysis reveals monocyte alterations and molecular signatures of inflammatory-coagulation crosstalk in long COVID

A comparison of 21 people with long COVID and 24 asymptomatic controls found lower white-cell, monocyte, and platelet counts and longer APTT. Integrated with a separate public transcriptomic dataset, the findings support a proposed inflammation-coagulation model, but the small and non-identical datasets cannot establish mechanism.

Thai researchersParin Kamseng · Namngern Chantaramanee · Rittikorn Sompan · Sarayot Rareongjai
Public Health74IMPACT SIGNAL
Evidence of global relevance

Toxicological Assessment of Oligofructans Derived from Raw Sugar Fermentation by Bacillus subtilis TISTR 001 and Their Modulatory Effects on Rat Gut Microbiota

Thai researchers evaluated oligofructans produced from raw sugar using Bacillus subtilis TISTR 001. Rats showed no treatment-related mortality or toxicity at doses up to 2,000 mg/kg/day for 90 days, alongside reported shifts in gut microbial taxa. These are preclinical animal findings and do not establish human safety or benefit.

Thai researchersSirinya Taya · Boontiwa Ninchan · Sonthaya Umsumarng · Jutamat Klinsoda · Rawiwan Wongpoomchai · Charatda Punvittayagul
Environment and Engineering74IMPACT SIGNAL
Evidence of global relevance

A Multi-Frequency SAR Framework for Methane Emission Estimation in Thai Rice Paddies

A GISTDA-led framework combines Sentinel-1 and ALOS-2 radar with IPCC accounting to detect crop timing, classify water regimes, and estimate methane from irrigated rice in Thailand's central plain. Mean absolute error was 18.5 kg CH4/ha, but structural uncertainty in the IPCC Tier 1 emission factor exceeded all algorithmic errors combined.

Thai researchersNuntikorn Kitratporn · Kanjana Koedkurang · Panu Nueangjamnong · Kittiphop Simachokchai · Chompunut Chayawat
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Predictors of Early Recurrence and Survival Outcomes Following Curative Resection for Colorectal Liver Metastases and the Role of Salvage Surgery: A Retrospective Cohort Study

In a retrospective cohort of 109 patients undergoing liver resection for colorectal liver metastases, high tumor burden, major intraoperative blood loss, T3/T4 primary disease, and RAS mutation were associated with early recurrence. Selected patients undergoing salvage re-hepatectomy had favorable long-term survival, but small subgroups and strong selection bias prevent causal conclusions.

Thai researchersPipit Burasakarn · Nisanat Thongkua · Vachiraluck Chalokool · Anuparp Thienhiran · Sermsak Hongjinda · Pusit Fuengfoo
Mental Health74IMPACT SIGNAL
Evidence of global relevance

The Study of Efficacy and Safety of a Modified Chaihu Shugan San Formula in the Treatment of Insomnia Associated with Stress: A Pilot Clinical Evaluation

A 30-participant pre-post pilot reported lower sleep-quality and stress scores after four weeks of twice-daily modified Chaihu Shugan San, without clear liver or renal safety signals. Without randomization, a control group, or placebo, the study cannot separate the formula's effect from placebo, attention, or change over time.

Thai researchersPorwarut Srihara · Cao ZuoJun · Somratchanee Srifar · Mattanapat Phraecharoen
Clinical Medicine74IMPACT SIGNAL
Evidence of global relevance

Benefits of three consecutive sputum inductions using nebulized racemic salbutamol versus hypertonic saline in smear-negative or sputum-scarce pulmonary tuberculosis patients: a prospective randomized, double-blind study

In a randomized double-blind trial of 345 adults with suspected smear-negative or sputum-scarce pulmonary tuberculosis, three consecutive daily inductions with nebulized racemic salbutamol produced a higher combined smear-or-culture yield and fewer adverse events than 3% hypertonic saline. The single-center study evaluates specimen collection for diagnosis, not tuberculosis treatment outcomes.

Thai researchersWarangkana Keeratichananont · Suriya Keeratichananont · Natthaphon Ubonsutvanich · Jirachaya Chaisurote
Thai Fruit and Diabetic Retinal Mechanisms74IMPACT SIGNAL
Evidence of global relevance

ANTIOXIDANT AND ANTI-APOPTOTIC ACTIVITIES OF MAKIANG FRUIT EXTRACT IN ARPE-19 CELLS EXPOSED TO GLUCOSE-INDUCED CELLULAR DAMAGE

A 95% ethanol makiang-fruit extract showed antioxidant activity and, when co-administered in 30 mM glucose-exposed ARPE-19 cells, the highest 200 microgram/mL dose increased viability by 15.4%, reduced ROS by 37.8%, and lowered caspase-9 and -3 activities.

Thai researchersNuntaporn Chanpurk · Kemika Praengam · Angkalsiri Deeaum · Pasitta Panritdum · Monruedee Sukprasansap · Chawanphat Muangnoi
Green-Tea Compounds and Diabetic Kidney Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Epigallocatechin-3-gallate, l-theanine and theophylline abolish high-glucose-induced renal cell senescence and subsequent epithelial-mesenchymal transition and fibroblast activation via SIRT1/PGC-1α axis: Implications for diabetic kidney disease

High glucose induced senescence in proximal tubular cells, whose SASP-conditioned medium then triggered epithelial-mesenchymal transition in distal tubular cells and fibroblast activation. EGCG, L-theanine, and theophylline suppressed these effects while restoring SIRT1/PGC-1alpha signaling.

Thai researchersRattiyaporn Kanlaya · Sunisa Yoodee · Kanokwan Nonthawong · Chonicha Subkod · Supanan Nanthawuttiphan · Visith Thongboonkerd
Curcumin and Breast-Tumor Immunity74IMPACT SIGNAL
Evidence of global relevance

Curcumin Attenuates Breast Cancer Cell-induced Inflammasome Activation via the NOD-like receptor protein 3/Caspase-1/Interleukin-1β Axis

Breast-cancer-cell conditioned medium drove THP-1-derived macrophages toward a pro-inflammatory tumor-associated phenotype with higher IL-1beta, NLRP3, and caspase-1. Curcumin pretreatment reduced IL-1beta secretion, NLRP3 protein, and IL1B/CASP1 transcripts.

Thai researchersKhwandow Kunchana · Wattanased Jarisarapurin · Suvara K. Wattanapitayakul
Encephalitis Viruses and Cell-Death Mechanisms74IMPACT SIGNAL
Evidence of global relevance

Inhibition of calpain-mediated BAX cleavage attenuates Japanese encephalitis virus-induced apoptosis in SH-SY5Y neuroblastoma cells

In SH-SY5Y cells, Japanese encephalitis virus activated calpain to cleave BAX into p18 BAX, which moved to mitochondria and triggered cytochrome c, caspase-3, PARP cleavage, and apoptosis. The calpain inhibitor calpeptin attenuated these signals and improved cell viability.

Thai researchersKuntida Kitidee · Arisara Samutpong · Nattaporn Pakpian · Montri Yasawong · Prapimpun Wongchitrat
Occupational Lung Health and AI Screening74IMPACT SIGNAL
Evidence of global relevance

Artificial neural network modelling using complete blood count for the early detection of black lung disease among Indonesian coal miner: A retrospective longitudinal study

Annual health data from 807 Indonesian coal miners followed from 2013-2021 showed 13.9% cumulative black-lung incidence. A complete-blood-count neural network and Cox model both identified eosinophils and monocytes as influential predictors.

Thai researchersKurnia Ardiansyah Akbar · Kraiwuth Kallawicha · Pallop Siewchaisakul
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
70IMPACT SIGNAL
Multidisciplinary

Contributions of a small collection of the terrestrial microsnails genus Diplommatina s.l. (Caenogastropoda, Cyclophoroidea, Diplommatinidae) from Myanmar, with a catalogue of recorded species and description of two new species

ZooKeys

Thailand-affiliated authors
Piyoros Tongkerd · Arthit Pholyotha · Supunya Annate · Chirasak Sutcharit
Institutions
Chulalongkorn University
70IMPACT SIGNAL
Multidisciplinary

Diplommatina angulata Theobald & Stoliczka 1872

Open MIND

Thailand-affiliated authors
Piyoros Tongkerd · Arthit Pholyotha · Supunya Annate · Chirasak Sutcharit
Institutions
Chulalongkorn University
70IMPACT SIGNAL
Clinical Medicine

From Biofortification to HT-29 Growth Inhibition: Selenium-Enriched Sunflower Sprouts Modulate Apoptosis- and Cell Cycle-Related Markers

Foods

Thailand-affiliated authors
Piyanete Chantiratikul · Anut Chantiratikul · Yada Laotongsan · Gondanai Lasungneon · Worachot Saengha · Thipphiya Karirat · Piyathida Promjamorn · Vijitra Luang‐In
Institutions
Mahasarakham University
70IMPACT SIGNAL
Clinical Medicine

Sustained reduction in blood culture utilization following a crisis-driven diagnostic stewardship intervention

Infection Control and Hospital Epidemiology

Thailand-affiliated authors
Alan E. Gross
Institutions
Chulalongkorn University
70IMPACT SIGNAL
Multidisciplinary

Diplommatina tumida subsp. laisenensis Gude 1921

Open MIND

Thailand-affiliated authors
Piyoros Tongkerd · Arthit Pholyotha · Supunya Annate · Chirasak Sutcharit
Institutions
Chulalongkorn University
70IMPACT SIGNAL
Multidisciplinary

Optimization of rosmarinic acid extraction from Thunbergia laurifolia leaves using a green solvent and evaluation of its biological activities

Scientific Reports

Thailand-affiliated authors
Kotchaphan Chooluck · Amaraporn Wongrakpanich · Warisara Parichatikanond · Brompoj Prutthiwanasan · Naphatson Chanthathamrongsiri
Institutions
Mahidol University · Burapha University
70IMPACT SIGNAL
Engineering

Fragility-based seismic evaluation and GFRP retrofitting of short-span bridge piers in Thailand’s seismic zones

Results in Engineering

Thailand-affiliated authors
Phoonsak Pheinsusom · Chayut Ngamkhanong · Panon Latcharote · Qudeer Hussain · Chatpan Chintanapakdee · Tidarut Jirawattanasomkul · Tamon Ueda
Institutions
Chulalongkorn University · Mahidol University
70IMPACT SIGNAL
Environmental Engineering

Interfacial Ligand Density Regulates Solvent-Induced Phase Transformation in CsPbBr 3 /Cs 4 PbBr 6 Nanocrystals

Chemistry of Materials

Thailand-affiliated authors
Tetsuya Kida
Institutions
Chulalongkorn University
70IMPACT SIGNAL
Clinical Medicine

Risk assessment of subclinical mastitis in Holstein cows in Jiangsu Province of China

Frontiers in Veterinary Science

Thailand-affiliated authors
Niel A. Karrow
Institutions
Department of Livestock Development
70IMPACT SIGNAL
Global Public Health

The PAU Survey: Uncovering the connection between intrinsic and observed galaxy properties using symbolic regression

Monthly Notices of the Royal Astronomical Society

Thailand-affiliated authors
Suttikoon Koonkor
Institutions
National Astronomical Research Institute of Thailand
70IMPACT SIGNAL
Clinical Medicine

Effect of Titanium Dioxide Nanoparticle-Reinforced Silicone Elastomers on Candida albicans Adhesion

European Journal of Dentistry

Thailand-affiliated authors
Sasiwimol Sanohkan · Kemarajt Kemavongse
Institutions
Prince of Songkla University
70IMPACT SIGNAL
Clinical Medicine

Intravascular behavior of cutaneous polynucleotide injectables following intra-arterial exposure

Scientific Reports

Thailand-affiliated authors
Suphagan Boonpethkaew · Atchima Suwanchinda · Werayut Yingmema · Wilai Thanasarnaksorn
Institutions
Thammasat University · Mahidol University · Ramathibodi Hospital · Rangsit University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link