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EDITORIAL DEEP DIVES

In-depth research analyses

Source-verified editorial analyses, ordered by latest publication date

972 analyses
Clinical Medicine89IMPACT SIGNAL
Global potential

Visual Impairment Was Associated With Nearly Threefold Higher Odds of Frailty Progression in Thai Older Adults

This retrospective cohort from the Siriraj Primary Care Unit followed 400 community-dwelling older adults, with a median age of 70 years and 76% women. Visual impairment was defined as visual acuity worse than 6/12 in the better-seeing eye, and frailty was assessed with the Thai FRAIL scale. Ordinal logistic regression found an association with transition to a worse frailty state: adjusted odds ratio 2.98 (95% CI 1.97–4.52; p

Thai researchersChutimon Thongkhao-On · Harisd Phannarus · Aliyah Famitynond · Pornchita Thanakorn · Thitiya Jenjirojpipat · Thiwarut Kraikaitsakul · Varalak Srinonprasert
Fundamental Cancer Biology89IMPACT SIGNAL
Global potential

NECTIN2 Depletion Cut Migration and Invasion by About Half, but Only in One Triple-Negative Breast Cancer Cell Line

This study asked whether the cell-surface adhesion molecule NECTIN2 contributes to motility and invasion in triple-negative breast cancer. The team combined public-dataset analyses with stable NECTIN2 depletion in MDA-MB-231 and MDA-MB-468 cells. The major phenotype was confined to MDA-MB-231: migration and invasion fell by about 50%, accompanied by lower LIMK1 and cytoskeletal changes, while LIMK1 re-expression partially restored migration. The findings support a context-dependent mechanism, not a clinically validated drug target or proof that NECTIN2 inhibition prevents metastasis in patients.

Thai researchersPhatchanat Klaihmon · Pattaratorn Muangtate · Sudarat Thongphayong · Puretat Saetan · Supasorn Chanthateyanonth · Chanitra Thuwajit · Surapol Issargrisil · Phatchariya Phannasil
Antimicrobial Stewardship92IMPACT SIGNAL
Stepped-Wedge Cluster Randomized Trial

A Smartphone Antimicrobial Prescribing App Did Not Outperform Paper Guidelines Across Six Lao Hospitals

Across a stepped-wedge cluster randomized trial in six Lao hospitals, a smartphone version of national antimicrobial prescribing guidelines plus one stewardship training session did not significantly improve adherence over paper versions after adjustment for time, clustering, and confounders. Inpatient adherence was 25.6% versus 17.0% before adjustment, but the adjusted odds ratio was 1.26 (95% CI 0.8–1.9; p=0.276); outpatient results were also null. The finding argues for sustained, multifaceted stewardship rather than guideline access alone.

Thai researchersSue J. Lee · Mavuto Mukaka · Nicholas P. J. Day · Paul N. Newton
Digital Health and Nutrition92IMPACT SIGNAL
Model-development and benchmark evidence

Two-Stage Model Classifies 46 Produce and Vegetable-Dish Categories at 92.43% Top-1 Accuracy, but Lacks On-Device Validation

The study developed a two-stage ThaiSook pipeline: a binary model first rejects non-produce images, after which a multiclass model identifies 43 fruit and vegetable types and three vegetable-heavy dishes. The 40,595-image dataset contained 11,210 labelled and 29,385 unlabelled user images. With label smoothing and temperature scaling, the pipeline reached 92.43% top-1, 94.56% top-3, and 94.91% top-5 accuracy; Noisy Student raised top-1 accuracy to 92.59%. However, results rely on one train–test split, without real on-device testing or evidence that classification improves dietary measurement or health outcomes.

Thai researchersDecho Surangsrirat · Panyawut Sri-iesaranusorn · Polathep Vichitkunakorn
Health Policy and Cancer-Medicine Access88IMPACT SIGNAL
Global potential

Lower-Income Asia-Pacific Settings Reported Full Out-of-Pocket Cost for 95.2% of High-Benefit Medicine–Country Pairs

This predefined regional analysis of ESMO's 2023 global survey covered 20 Asia-Pacific countries and compared WHO essential cancer medicines with high-benefit medicines under ESMO-MCBS. The findings show that marketing availability does not equal reliable access: reimbursement and patient out-of-pocket burden remain major bottlenecks. Access was generally stronger in high-income economies, while middle- and lower-income groups faced large gaps, particularly for high-benefit medicines. The evidence is expert-reported and cross-sectional, and income-group aggregates must not be presented as Thailand-specific estimates.

Thai researchersNaiyarat Prasongsook · Lucksamon Thamlikitkul
Geospatial Agriculture and Environment89IMPACT SIGNAL
Regional model-validation evidence

GEDI–Sentinel Model Maps Northeast Thai Rubber at 82.63% Accuracy but Struggles With Young Plantations

This study mapped 2024 rubber distribution and age structure across Northeast Thailand using Random Forest in Google Earth Engine, combining Sentinel-1, Sentinel-2, vegetation indices, and a GEDI-trained canopy-height model. Three-class rubber mapping reached 82.63% overall accuracy and about 0.84 F1; three-group age classification reached 83.39%. Plantations older than seven years dominated and were classified more reliably than young stands. The output is a regional monitoring baseline, not an error-free parcel-level decision map.

Thai researchersSavittri Ratanopad Suwanlee · Muhammad Hanif · Surasak Keawsomsee · Kemin Kasa · Narissara Nuthammachot · Sarawut Ninsawat · Jantima Polpinij · Jaturong Som-Ard
Medical Education and Serious-Illness Care89IMPACT SIGNAL
Longitudinal training evidence

Advance-Care-Planning Training Raised Residents’ Knowledge From 7.74 to 8.65, but Had No Control Group

This mixed-methods evaluation tested an Advance Care Planning programme combining role-play, personal-value reflection, and two Circle of Learning sessions with an entire cohort of 50 first-year internal-medicine residents. Longitudinal analysis used 34 complete cases through 15 months, and 10 residents were interviewed. Knowledge rose from 7.74 to 8.65 out of 9, alongside several attitude and confidence improvements. Interviewees said role-play bridged theory and practice but identified a need for ongoing workplace support. The evidence concerns learner readiness, not observed conversation quality or patient outcomes.

Thai researchersThagoon Kanjanopas · Smuch Siramongkholkarn · Wanna Jarusomboon · Ekkapop Sittiwantana · Arisa Phochaisarn · Saipin Hathirat · Saran Thanapluetiwong
Public Health and Migrant Health92IMPACT SIGNAL
Evidence of global relevance

Migrant TB Patients Chose Months-Long Sanatorium Care to Pursue Cure Amid Cost, Transport, and Documentation Barriers

This multi-perspective qualitative study at the SMRU tuberculosis sanatorium in Mae Ramat, Tak Province, examined why migrants choose long residential treatment. It included 37 unique patients—33 who chose the sanatorium and four who chose community DOTS—plus five health workers. Three themes organized the findings: desire for cure, barriers to diagnosis and treatment, and community and organizational support.

Thai researchersJindaporn Wirachonphaophong · Hai Ti Ti · Nay Kaw Htoo · Kanjana Winyoorat · Cha Ba · San Soe · Suphak Nosten · Htet Ko Ko Aung · Sein Sein Thi · Francois Nosten
Public Health and Health Systems92IMPACT SIGNAL
Qualitative evidence for service design

Patients in South Ethiopia Know How to Manage Diabetes, but Drug Shortages and Costs Undercut Self-Care

This qualitative study examined diabetes self-care in three South Ethiopian hospital clinics. Its 21 participants comprised 12 adults with type 2 diabetes and nine healthcare providers. Patients described medication, diet, physical activity, foot care, and glucose monitoring as daily work negotiated against financial pressure, drug shortages, beliefs, food costs, limited support, and health-system constraints. Patients tended to foreground structural barriers, whereas providers placed more emphasis on knowledge and forgetting advice. Continued counselling, reliable medicines, and peer support emerged as priorities, but these are interview-derived design directions rather than tested interventions.

Thai researchersTemesgen Anjulo Ageru · Cua Ngoc Le · Apichai Wattanapisit · Charuai Suwanbamrung
International Journal of Qualitative Studies on Health and Well-beingRead analysis →
Forest Policy and Bioeconomy92IMPACT SIGNAL
Evidence of global relevance

Perspectives on the forest bioeconomy: insights of stakeholders from cases in Central Europe and the Mekong region

This comparative study examines how 336 purposively recruited respondents in Czechia, Slovakia, Thailand, Laos and Vietnam understand and assess the forest bioeconomy. Respondents generally reported stronger familiarity with sustainable forest management and the circular economy than with the bioeconomy itself. Perceptions also varied across country cases, particularly within the Mekong region. A binary logistic regression identified associations between high perceived implementation and country, age, education, understanding of policy aims, support for implementation and positive assessments of forest-industry implementation. These findings describe perceptions within the recruited sample rather than national populations, and the reported associations should not be interpreted as causal effects.

Thai researchersNopparat Kaakkurivaara · Alice Sharp · Prasit Wangpakapattanawong
One Health and Zoonotic-Disease Prevention92IMPACT SIGNAL
Formative evidence for One Health intervention design

Zoonotic Risk in Rural Nan Is Not Just Behavioural: Water Scarcity, Forest Change, and Food Systems Connect Five Interfaces

Researchers examined everyday practices and conditions that could enable cross-species transmission in four rural villages in Nan Province, organising findings into five interfaces: human–animal, human–environment, human-human, animal–animal, and animal–environment. The picture is not simply one of deficient knowledge. Animal contact, butchering and food preparation, water scarcity and contamination, waste, forest change, intensified agriculture, mixed-species proximity, and multilingual communication operate as a system. Community leaders and village health volunteers were viewed as trusted messengers. The study therefore recommends education that combines knowledge, skills, practical tools, and recognition of structural limits, but it neither completed nor evaluated the final intervention.

Thai researchersMonchai Phongsiri · Simaphon Tomklang · Theerayuth Labooth · Thanapat Chaibut · Pongsakon Jaruton · Kotthamon Chanprathad · Sarutaya Suphawatthanaphan · Hans Overgaard · Patcharin Lapanun
Circular Bioeconomy and Seafood Technology92IMPACT SIGNAL
Comprehensive narrative-review evidence

Crustacean By-Products Hold High-Value Compounds, but ‘Green’ Extraction Still Lacks LCA and Industrial Proof

This review compares conventional acid–alkali and solvent extraction with supercritical fluids, enzymatic hydrolysis, pulsed electric fields, ultrasound, cold plasma, microwave, high-pressure processing, and deep eutectic solvents for recovering bioactives from crustacean by-products. No technology is universally optimal: conventional methods retain advantages in simplicity and maturity, while emerging methods may reduce chemicals or better preserve product quality but face equipment, cost, energy, reproducibility, and pilot-scale constraints. The paper is therefore a map of options and evidence gaps, not proof that one technology is the ‘most sustainable.’

Thai researchersAkanksha R. Gautam · Soottawat Benjakul · Rattikarn Boonchoosri · Nilesh Nirmal · Avtar Singh
BIBLIOGRAPHIC RESEARCH WATCHLIST

Bibliographic research records

Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.

1,808records
1,808 records
75IMPACT SIGNAL
Clinical Medicine

Factors predicting self-protective behaviors against PM2.5 exposure among rural community-dwelling older adults in the Central Region of Thailand: A cross-sectional study

Journal of Public Health and Development

Thailand-affiliated authors
Winthanyou Bunthan · Anchalee Ngamchantratip · Pirunlak Jitdorn · Jariyawat Kompayak
Institutions
Huachiew Chalermprakiet University · Chonburi Hospital
75IMPACT SIGNAL
Environmental Engineering

A satellite-based geospatial framework for screening potential artificial light at night exposure in rice-growing landscapes: a nationwide case study in Thailand

Environmental Research Communications

Thailand-affiliated authors
Thanayut Changruenngam · F. Surina · Kritsaphong Phasitvilaitham · Suruswadee Nanglae · Jumrus Klinhnu
Institutions
Chiang Rai Rajabhat University
75IMPACT SIGNAL
Clinical Medicine

Multi-Target Pharmacological Mechanisms of Cannabidiol in Breast, Colorectal, and Lung Cancer: An Integrated Network Pharmacology and Molecular Docking Study

Journal of Phytomedicine

Thailand-affiliated authors
Omar Villalobos
Institutions
Chulalongkorn University
75IMPACT SIGNAL
Energy and Materials

Development and catalytic performance of metal-impregnated porous clay heterostructures for efficient steam methane reforming

Next Materials

Thailand-affiliated authors
Thanapat Chomchatwarl · Nollapan Nootsuwan · Chatchai Veranitisagul · Navadol Laosiripojana · Apirat Laobuthee
Institutions
Kasetsart University · Rajamangala University of Technology · Joint Graduate School of Energy and Environment · The Royal College Of Anesthesiologists Of Thailand · King Mongkut's University of Technology Thonburi
75IMPACT SIGNAL
Multidisciplinary

Serum Prolactin and Bone Mineral Density in Women with Schizophrenia Receiving Prolactin-Raising Antipsychotics: A Cross-Sectional Study

Pharmacoepidemiology

Thailand-affiliated authors
Kamonrat Somrak · Chompoonuch Werawattanachai · Apiradee Sangngarm · Sipanut Silaket · Tuanthon Boonlue
Institutions
Sappasithiprasong Hospital · Ubon Ratchathani University
75IMPACT SIGNAL
Engineering

Sustainable lightweight alkali-activated FA-OPC concrete incorporating recycled EPS foam and seawater: Mechanical, thermal, and acoustic performances

Case Studies in Construction Materials

Thailand-affiliated authors
Prach Amornpinyo · Attaphol Bubpi · Yongyuth Sirisripetch · Preechawut Srirueng · Sumrerng Rukzon · Phongphan Tankasem · Patcharapol Posi · Prinya Chindaprasirt
Institutions
Rajamangala University of Technology Isan · Khon Kaen University · Rajamangala University of Technology Rattanakosin · Mahasarakham University · The Royal College Of Anesthesiologists Of Thailand
75IMPACT SIGNAL
Environmental Engineering

Diatomite and Fly Ash Enhance Silicon Availability, Nutrient Uptake, and Yield of Sweet Corn in Humid Tropical Sandy Loam

Soil Systems

Thailand-affiliated authors
Worawalun Pacharasirikul · Somchai Anusontpornperm · Suphicha Thanachit · Mutchima Phun-iam
Institutions
Kasetsart University
75IMPACT SIGNAL
Global Public Health

Proximate Composition Profiling and Adjustment of Near-Infrared Spectroscopy (NIRS) Equations for Dry Legumes from Local Markets in Northern Thailand and Southern China

Agriculture

Thailand-affiliated authors
Patipon Teerakitchotikan · Sarana Rose Sommano · Tibet Tangpao
Institutions
Chiang Mai University
75IMPACT SIGNAL
Environmental Engineering

Life cycle assessment of benzoxazinone synthesis: Comparative evaluation of alternative synthetic pathways

Cleaner Engineering and Technology

Thailand-affiliated authors
Anuchit Wuttitrairat · Wasan Kongnaikhaw · Soottiwan Thamsakon · Wachira Daosud · Weerawun Weerachaipichasgul · Paisan Kittisupakorn
Institutions
Chulalongkorn University · Burapha University · Naresuan University
75IMPACT SIGNAL
Clinical Medicine

Pythium keratitis: experience from Thailand

British Journal of Ophthalmology

Thailand-affiliated authors
Vilavun Puangsricharern · Thanachaporn Kittipibul · Wasee Tulvatana
Institutions
Chulalongkorn University
75IMPACT SIGNAL
Engineering

Seismic hazard analysis and risk classification for major dams in Thailand: a nationwide study

Geoenvironmental Disasters

Thailand-affiliated authors
Santi Pailoplee · Chutimon Promsuk · Premwadee Traitangwong · Santawat Sukrungsri · Sutthikan Khamsiri
Institutions
Chulalongkorn University · Thai Health Promotion Foundation · Kanchanaburi Rajabhat University
75IMPACT SIGNAL
Environmental Engineering

Rainfall Variability Impacts on Runoff and Reservoir Inflow in a Small Mountainous Watershed: SWAT-Based Assessment in the Upper Ing River Basin, Northern Thailand

Water

Thailand-affiliated authors
Krisdha Thanawong · Krisdha Thanawong · Asmat Ullah · Kittipong Vuthijumnonk · Kwansirinapa Thanawong · Kwansirinapa Thanawong
Institutions
University of Phayao · Kasetsart University
75IMPACT SIGNAL
Clinical Medicine

Distribution and viral load of canine respiratory coronavirus in naturally infected dogs: evidence from clinical sampling sites and tissue detection

BMC Veterinary Research

Thailand-affiliated authors
Panida Poonsin · Aisyah Nikmatuz Zahro · Vorapun Wiwatvisawakorn · Panitnan Punyathi · Sitthichok Lacharoje · Chutchai Piewbang · Somporn Techangamsuwan
Institutions
Chulalongkorn University · Bangkok Hospital
75IMPACT SIGNAL
Digital Health

Estimating Canopy Isoprene Concentrations over a Deciduous Dipterocarp Forest in Northern Thailand Using a Calibrated Box Model and Physics-Informed Machine Learning: A Pilot Study

Atmosphere

Thailand-affiliated authors
Anchisa Phaichot · Teerachai Amnuaylojaroen · Phakinee Kayong · Radshadaporn Janta · Vanisa Surapipith · Ronald Macatangay
Institutions
University of Phayao · National Astronomical Research Institute of Thailand · Chiang Mai University · UNICEF East Asia and Pacific Regional Office
75IMPACT SIGNAL
Clinical Medicine

In vitro susceptibility and provisional epidemiological cutoff values for eight antifungal agents against Trichophyton mentagrophytes and Trichophyton interdigitale : a multicenter study from China

Journal of Clinical Microbiology

Thailand-affiliated authors
Hailin Zheng · Wenting Xie · Xue Kong · Naicen Ge · Huan Mei · Xiaodong She · Weida Liu · Guanzhao Liang · Xiaofang Li
Institutions
Institute of Dermatology
75IMPACT SIGNAL
Clinical Medicine

Coenocline Simulation of Microbiome Samples: A Biologically Mechanistic Framework for Generating Ecologically Realistic Synthetic Datasets to Support Classification Method Evaluation

Pathogens

Thailand-affiliated authors
Cameron Hurst · Dhammika Leshan Wannigama · Pichaya Tantiyavarong · Nop Khongthon
Institutions
Thammasat University · Mahidol University
75IMPACT SIGNAL
Energy and Materials

Integrated Phytochemical, Network Pharmacology, and Molecular Docking Analyses of Triphala Extract Reveal Protective Effects Against H2O2-Induced Oxidative Hemolysis in G6PD-Deficient Erythrocytes

Life

Thailand-affiliated authors
Aman Tedasen · Siriwimon Ranjuanjit · Nattacha Srirod · Kingkan Bunluepuech · Veeranoot Nissapatorn · Chutima Rattanawan · Naunpun Sangphech · Rachasak Boonhok · Orawan Sarakul
Institutions
Walailak University · Mahidol University · Thammasat University
75IMPACT SIGNAL
Clinical Medicine

Selective Root Canal Retreatment as an Alternative Option in Patient at Risk of MRONJ: A Case Report

Oral Sciences Reports

Thailand-affiliated authors
Jiraphak Jaturont · Thanawut Khongpreecha · Panupol Kunasarapun
Institutions
Mahidol University
75IMPACT SIGNAL
Clinical Medicine

Immune-intrinsic MLKL regulates dendritic cell maturation and CD8+ T cell effector function in anti-tumor immunity

Biology Direct

Thailand-affiliated authors
Nattaya Duangthim · Siriporn Jitkaew
Institutions
Chulalongkorn University
75IMPACT SIGNAL
Clinical Medicine

Mitochondria-Targeted Natural-Derived Compounds in Cellular Senescence: Mechanisms, Therapeutic Potential, and Future Directions

Biology

Thailand-affiliated authors
Jirapat Namkaew · Thiranut Jaroonwitchawan
Institutions
Walailak University
75IMPACT SIGNAL
Digital Health

Identifying Potassium-Associated Ecological Transition Zones for Mimosa pigra Invasion Using Explainable Machine Learning and Bayesian Inference

Biology

Thailand-affiliated authors
Bhuvadol Gomontean · Khemmanant Khamthong
Institutions
Mahasarakham University
75IMPACT SIGNAL
Clinical Medicine

The Performance of the STRONGkids Nutrition Screening Tool Following Nurse Training in a Tertiary Care Setting

Journal of Paediatrics and Child Health

Thailand-affiliated authors
Punthita Ngamboriruk · Oraporn Dumrongwongsiri · Phanphen Phoonlapdacha
Institutions
Mahidol University · Ramathibodi Hospital
75IMPACT SIGNAL
Global Public Health

Seasonal effects on ruminal fermentation and greenhouse gas emission patterns in non-lactating crossbred Saanen goats under tropical conditions: Evidence from respiratory chamber measurements

Veterinary World

Thailand-affiliated authors
Nhung Thi Cam Pham · Narongsak Chaiyabutr · Sumpun Thammacharoen
Institutions
Chulalongkorn University
EDITORIAL STANDARD

How we select research

We use OpenAlex, Crossref, PubMed, DOI records, and publisher pages, then verify Thai researcher participation before publication.

  1. 01Discover new researchFocus on the latest 90 days and verifiable Thai affiliations
  2. 02Assess signalsReview recency, quality, collaboration, and societal relevance
  3. 03Read with careReport findings with limitations and avoid claims beyond the evidence
  4. 04Open original sourcesEvery item includes a DOI, review date, and verification link