Phetchabun Screens 97.3% for HCV; 96.4% of SVR12-Evaluable Patients Are Cured, but Transmission Elimination Is Unproven
Phetchabun’s micro-elimination programme linked fingerstick anti-HCV testing, HCV-RNA confirmation, and 12-week sofosbuvir/velpatasvir treatment through primary-care and district-hospital services across all 11 districts under universal health coverage. From 2020 to April 2026, 389,547 of 400,567 targeted people were screened (97.25%); 14,845 of 18,340 anti-HCV-reactive participants received RNA confirmation (80.94%), identifying 10,996 active infections. Of 8,961 treatment-eligible patients, 8,842 received therapy (98.67%); among 6,719 evaluated at SVR12, 6,474 were cured (96.35%). The programme demonstrates province-scale test-to-treat feasibility, but not yet the incidence or mortality reductions required for elimination.
Wijitra Phaengkha · Pornjarim Nilyanimit · Nungruthai Suntronwong · Jiratchaya Puenpa · Duong Hoang Huy Le · Saranya Ngamnimit · Pattama Janpathip · Lapasrada Kamput · Kawin Thongnoi · Wanalee Toomta · Phatcha Wohanklong · Jarunlak Saokeaw · Niphapornt Thammajit · Suwannee Rerngleum · Ananyalak Yoisara · Nitiya Srisuk · Jidapa Suwannachat · Anchalee Karagate · Rujipat Wasitthankasem · Yong PoovorawanNam Nao Hospital, Phetchabun · Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University · Phetchabun Provincial Public Health Office · Phetchabun Hospital · Buengsamphan Hospital · Lomsak Hospital · Chondaen Hospital · Si Thep Hospital · Wang Pong Hospital · Wichianburi Hospital · Lomkao Crown Prince Hospital · Nongphai Hospital · Khao Kho Hospital · National Center for Genetic Engineering and Biotechnology, NSTDA · The Royal Society of Thailand
A post hoc analysis of the DEN-301 placebo arm followed 30,620.6 person-years, identifying 560 virologically confirmed dengue cases among 9,698 febrile illnesses; 142 cases, or 25.4%, were hospitalized.
A 20-year-old man on automated peritoneal dialysis developed vague abdominal symptoms, weight loss and declining ultrafiltration. Repeated dialysate cultures, acid-fast staining and molecular tests were negative despite mononuclear-predominant leukocytosis. Contrast CT identified peritoneal nodules, CT peritoneography showed a trapped dialysate pocket, and targeted biopsy demonstrated necrotising granulomatous inflammation. Tissue culture grew M. kansasii resistant to rifampicin, moxifloxacin and ciprofloxacin.
HITAP reviewed 278 HTA capacity-strengthening activities in 25 countries from 2010 to mid-2025. Asia accounted for 151 activities and 128 engagements were programmatic rather than ad hoc. Knowledge sharing represented 26% and research or project collaboration 21%. Among 11 African partner countries, only three had programmatic engagement, accounting for 30 activities.
Morphology combined with ITS, LSU, rpb2 and β-tub phylogenies distinguished Nigropunctata pseudohydei as a new species and confirmed the first Thai record of N. complanata.
Thai researchersZaw Lin Tun · Digvijayini Bundhun · Kevin D. Hyde
An eight-country perspective argues that telemedicine, wearables and home sensors, augmented AI and mobile health can distribute expertise, observe symptoms between visits and support self-management, particularly where neurologists are scarce. Impact depends on infrastructure, interoperability, workforce, governance and equity-first hybrid care, not devices alone.
DJC6219 and NK62157 were isolated from municipal wastewater and characterised through host-range assays, electron microscopy, stability, multiplicity-of-infection optimisation, growth kinetics and genomics.
The authors review challenges in estimating preventable AMR burden and advocate explicit counterfactuals, confounding control and principled combination of individual studies.
Thai researchersCherry Lim · Sue J. Lee · Yin Mo · Ben S. Cooper
Ten Asia-Pacific experts developed 11 consensus statements on mild traumatic brain injury and use of GFAP/UCH-L1 within 12 hours. Final agreement was 90-100%, emphasizing biomarkers as adjuncts while clinical assessment and locally available imaging remain central.
RGD-functionalized cannabidiol lipid nanoparticles increased cellular uptake threefold and in-vitro BBB transport by 65%, while reducing inflammatory and oxidative markers. In a preclinical Alzheimer's model, cognition, Aβ/tau pathology, metabolism and gut-barrier indicators improved. The findings are promising but not evidence in patients.
Researchers used the UNDRR Stop Disasters online game with students, water professionals and community members in Thailand and Malaysia. A post-game survey of 35 participants found high enjoyment, lively interaction and perceived reinforcement of declarative flood-management knowledge.
Among 1,870 critically ill patients with acute kidney injury, sodium and potassium from arterial blood-gas analysers showed relatively good agreement with central laboratory values, with potassium having the narrowest limits. Clinically meaningful discrepancies occurred in 7.0% of sodium, 14.1% of potassium and 31.4% of chloride measurements, so rapid bedside results should support rather than replace reference testing.
This multicentre secondary analysis used the validated 2018–2020 TH-SOSGOQ 2.0 database. The full cohort included 68 patients and the reliability/construct-validity cohort 64. Mean age was 57 years and 55.9% were women. Internal consistency was 0.832 and test-retest ICCs ranged from 0.52 to 0.85.
Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.
3,510records
3,510 records
77IMPACT SIGNAL
Digital Health
AIoT-Based Energy-Efficient Temperature Regulation for Closed-System Greenhouses Using Classification-Based Control
ECTI Transactions on Computer and Information Technology (ECTI-CIT)
Extraction Optimization and Preliminary Neuroprotective Evaluation of Asiaticoside and Asiatic Acid from Centella asiatica (L.) Urb Using In Vitro and In Silico Approaches
Rapid simultaneous detection of katG S315T and rpoB S531L mutations for molecular screening of multidrug-resistant tuberculosis using a dual LAMP-lateral flow assay
Khon Kaen University · Synchrotron Light Research Institute
77IMPACT SIGNAL
Clinical Medicine
Image-derived conjunctival hyperemia and clinical ocular surface changes after initiation of topical glaucoma therapy: a prospective longitudinal pilot study
Predictors of the need for airway adjuncts during mask ventilation in Thai adult patients undergoing general anesthesia: A prospective observational study
Siriraj Hospital · Mahidol University · Mahidol Oxford Tropical Medicine Research Unit
77IMPACT SIGNAL
Clinical Medicine
Multidisciplinary providers’ perspectives on timely predialysis arteriovenous access preparation: An exploratory mixed-methods study in upper Northern Thailand
Baseline characteristics and practice patterns in geriatric vs. non-geriatric hemodialysis patients: initial results from a Thai nationwide multicenter prospective cohort (Thai-HDcohort)
Navamindradhiraj University · Chulalongkorn University · King Chulalongkorn Memorial Hospital · Phramongkutklao Hospital · Siriraj Hospital · Rajamangala Institute of kidney disease · Mahidol University · Ramathibodi Hospital · Chiang Mai University · Khon Kaen University · Prince of Songkla University · Srinakharinwirot University · Thammasat University · Bhumibol Adulyadej Hospital