PrEP Use and Willingness Cascades Among Transgender Women in 11 Asian Countries: Findings From the PrEP APPEAL Cross-Sectional Online Survey
The 2022 PrEP APPEAL online survey included 1,178 transgender women in 11 Asian countries. Awareness was 80.0%; among those aware, 62.6% had ever used PrEP, and 78.1% of ever-users were current users. Among higher-risk PrEP-naïve respondents, 60.0% were willing to use it, but only 34.0% of those willing would pay. Healthcare discrimination was associated with lower lifetime use; causality cannot be inferred.
Rena Janamnuaysook · Hua Boonyapisomparn · Nittaya PhanuphakChulalongkorn University · Institute of HIV Research and Innovation · Asia Pacific Transgender Network
A post hoc analysis of the DEN-301 placebo arm followed 30,620.6 person-years, identifying 560 virologically confirmed dengue cases among 9,698 febrile illnesses; 142 cases, or 25.4%, were hospitalized.
A 20-year-old man on automated peritoneal dialysis developed vague abdominal symptoms, weight loss and declining ultrafiltration. Repeated dialysate cultures, acid-fast staining and molecular tests were negative despite mononuclear-predominant leukocytosis. Contrast CT identified peritoneal nodules, CT peritoneography showed a trapped dialysate pocket, and targeted biopsy demonstrated necrotising granulomatous inflammation. Tissue culture grew M. kansasii resistant to rifampicin, moxifloxacin and ciprofloxacin.
HITAP reviewed 278 HTA capacity-strengthening activities in 25 countries from 2010 to mid-2025. Asia accounted for 151 activities and 128 engagements were programmatic rather than ad hoc. Knowledge sharing represented 26% and research or project collaboration 21%. Among 11 African partner countries, only three had programmatic engagement, accounting for 30 activities.
Morphology combined with ITS, LSU, rpb2 and β-tub phylogenies distinguished Nigropunctata pseudohydei as a new species and confirmed the first Thai record of N. complanata.
Thai researchersZaw Lin Tun · Digvijayini Bundhun · Kevin D. Hyde
An eight-country perspective argues that telemedicine, wearables and home sensors, augmented AI and mobile health can distribute expertise, observe symptoms between visits and support self-management, particularly where neurologists are scarce. Impact depends on infrastructure, interoperability, workforce, governance and equity-first hybrid care, not devices alone.
DJC6219 and NK62157 were isolated from municipal wastewater and characterised through host-range assays, electron microscopy, stability, multiplicity-of-infection optimisation, growth kinetics and genomics.
The authors review challenges in estimating preventable AMR burden and advocate explicit counterfactuals, confounding control and principled combination of individual studies.
Thai researchersCherry Lim · Sue J. Lee · Yin Mo · Ben S. Cooper
Ten Asia-Pacific experts developed 11 consensus statements on mild traumatic brain injury and use of GFAP/UCH-L1 within 12 hours. Final agreement was 90-100%, emphasizing biomarkers as adjuncts while clinical assessment and locally available imaging remain central.
RGD-functionalized cannabidiol lipid nanoparticles increased cellular uptake threefold and in-vitro BBB transport by 65%, while reducing inflammatory and oxidative markers. In a preclinical Alzheimer's model, cognition, Aβ/tau pathology, metabolism and gut-barrier indicators improved. The findings are promising but not evidence in patients.
Researchers used the UNDRR Stop Disasters online game with students, water professionals and community members in Thailand and Malaysia. A post-game survey of 35 participants found high enjoyment, lively interaction and perceived reinforcement of declarative flood-management knowledge.
Among 1,870 critically ill patients with acute kidney injury, sodium and potassium from arterial blood-gas analysers showed relatively good agreement with central laboratory values, with potassium having the narrowest limits. Clinically meaningful discrepancies occurred in 7.0% of sodium, 14.1% of potassium and 31.4% of chloride measurements, so rapid bedside results should support rather than replace reference testing.
This multicentre secondary analysis used the validated 2018–2020 TH-SOSGOQ 2.0 database. The full cohort included 68 patients and the reliability/construct-validity cohort 64. Mean age was 57 years and 55.9% were women. Internal consistency was 0.832 and test-retest ICCs ranged from 0.52 to 0.85.
Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.
3,510records
3,510 records
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Clinical Medicine
Core needle biopsy-derived breast cancer microtumors enable functional drug-response testing for precision oncology
Ratchathani University · Ubon Ratchathani University · Ubon Ratchathani Rajabhat University · Buriram Rajabhat University · Kalasin University
74IMPACT SIGNAL
Clinical Medicine
Determination of Exploratory Metastasis Biomarkers in Cancer of Unknown Primary Using Metastatic Colon Cancer as a Model: RNA Sequencing Bioinformatics Analysis
Mahidol University · Prapokklao Hospital · Rambhai Barni Rajabhat University · Burapha University · Asian Institute of Technology · National Science and Technology Development Agency · National Center for Genetic Engineering and Biotechnology
74IMPACT SIGNAL
Environmental Engineering
Modeling the impact of climatic variables on cereal crop production in the Terai region of Nepal
Mahidol University · Ramathibodi Hospital · Ramathibodi Chakri Naruebodindra Hospital
74IMPACT SIGNAL
Clinical Medicine
Association of Cardiovascular Risk Factors with Atherosclerotic Changes in Lower-Limb Donor Arteries for Free Flap Reconstruction: A CTA-Based Multivariate Analysis.