Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection
Two randomized controlled phase 3 trials are investigating the antisense oligonucleotide drug bepirovirsen in patients with chronic hepatitis B. with researchers from Chiang Mai University co-authoring
A post hoc analysis of the DEN-301 placebo arm followed 30,620.6 person-years, identifying 560 virologically confirmed dengue cases among 9,698 febrile illnesses; 142 cases, or 25.4%, were hospitalized.
A 20-year-old man on automated peritoneal dialysis developed vague abdominal symptoms, weight loss and declining ultrafiltration. Repeated dialysate cultures, acid-fast staining and molecular tests were negative despite mononuclear-predominant leukocytosis. Contrast CT identified peritoneal nodules, CT peritoneography showed a trapped dialysate pocket, and targeted biopsy demonstrated necrotising granulomatous inflammation. Tissue culture grew M. kansasii resistant to rifampicin, moxifloxacin and ciprofloxacin.
HITAP reviewed 278 HTA capacity-strengthening activities in 25 countries from 2010 to mid-2025. Asia accounted for 151 activities and 128 engagements were programmatic rather than ad hoc. Knowledge sharing represented 26% and research or project collaboration 21%. Among 11 African partner countries, only three had programmatic engagement, accounting for 30 activities.
Morphology combined with ITS, LSU, rpb2 and β-tub phylogenies distinguished Nigropunctata pseudohydei as a new species and confirmed the first Thai record of N. complanata.
Thai researchersZaw Lin Tun · Digvijayini Bundhun · Kevin D. Hyde
An eight-country perspective argues that telemedicine, wearables and home sensors, augmented AI and mobile health can distribute expertise, observe symptoms between visits and support self-management, particularly where neurologists are scarce. Impact depends on infrastructure, interoperability, workforce, governance and equity-first hybrid care, not devices alone.
DJC6219 and NK62157 were isolated from municipal wastewater and characterised through host-range assays, electron microscopy, stability, multiplicity-of-infection optimisation, growth kinetics and genomics.
The authors review challenges in estimating preventable AMR burden and advocate explicit counterfactuals, confounding control and principled combination of individual studies.
Thai researchersCherry Lim · Sue J. Lee · Yin Mo · Ben S. Cooper
Ten Asia-Pacific experts developed 11 consensus statements on mild traumatic brain injury and use of GFAP/UCH-L1 within 12 hours. Final agreement was 90-100%, emphasizing biomarkers as adjuncts while clinical assessment and locally available imaging remain central.
RGD-functionalized cannabidiol lipid nanoparticles increased cellular uptake threefold and in-vitro BBB transport by 65%, while reducing inflammatory and oxidative markers. In a preclinical Alzheimer's model, cognition, Aβ/tau pathology, metabolism and gut-barrier indicators improved. The findings are promising but not evidence in patients.
Researchers used the UNDRR Stop Disasters online game with students, water professionals and community members in Thailand and Malaysia. A post-game survey of 35 participants found high enjoyment, lively interaction and perceived reinforcement of declarative flood-management knowledge.
Among 1,870 critically ill patients with acute kidney injury, sodium and potassium from arterial blood-gas analysers showed relatively good agreement with central laboratory values, with potassium having the narrowest limits. Clinically meaningful discrepancies occurred in 7.0% of sodium, 14.1% of potassium and 31.4% of chloride measurements, so rapid bedside results should support rather than replace reference testing.
This multicentre secondary analysis used the validated 2018–2020 TH-SOSGOQ 2.0 database. The full cohort included 68 patients and the reliability/construct-validity cohort 64. Mean age was 57 years and 55.9% were women. Internal consistency was 0.832 and test-retest ICCs ranged from 0.52 to 0.85.
Thailand-affiliated bibliographic records. These are not full analyses; they are ordered by Impact Signal and should be verified against the original source.
3,510records
3,510 records
74IMPACT SIGNAL
Environmental Engineering
Valorization of mahogany sawdust waste for dyeing of cotton knitted fabrics using aloe vera and banana sap bio-mordants
Scientific Reports
Thailand-affiliated authors
M. R. Islam
Institutions
Asian Institute of Technology
74IMPACT SIGNAL
Environmental Engineering
Green, Sustainable, and Energy-Efficient System for Transportation Applications in IoT Edge-Cloud Networks
Scientific Reports
Thailand-affiliated authors
Pattaraporn Khuwuthyakorn · Orawit Thinnukool
Institutions
Chiang Mai University
74IMPACT SIGNAL
Global Public Health
Burnout, recovery, and flow in youth high-performance athletes: a multilevel mixed-methods examination of mental health and psychological functioning in Chinese athletes
Frontiers in Psychology
Thailand-affiliated authors
Yinan Zhang
Institutions
Suan Sunandha Rajabhat University
74IMPACT SIGNAL
Clinical Medicine
Tele-Group Cognitive Behavioural Family Intervention for Schizophrenia-Spectrum Disorders and Their Caregivers: A Feasibility Randomised Controlled Trial
Healthcare
Thailand-affiliated authors
Daniel Bressington
Institutions
Chiang Mai University
74IMPACT SIGNAL
Clinical Medicine
Ambient dose equivalent assessment from a pulsed electron beam using GEANT4-based Monte Carlo simulation
Nuclear Engineering and Technology
Thailand-affiliated authors
P. Jaikaew · Monchai Jitvisate · S. Rimjaem
Institutions
Chiang Mai University · Suranaree University of Technology · North Chiang Mai University · Chiang Mai Rajabhat University
74IMPACT SIGNAL
Clinical Medicine
Lyophilized LAMP Assay Combined with Lateral Flow Biosensor for Cold-Chain-Free Detection of Mycobacterium tuberculosis
Navamindradhiraj University · Vajira Hospital · Srinakharinwirot University · Kasetsart University
74IMPACT SIGNAL
Global Public Health
Effects of dietary pretreated anchovy waste on growth performance, meat composition, haematology and gut histology in quail
Scientific Reports
Thailand-affiliated authors
Hien Van Doan
Institutions
Chiang Mai University
74IMPACT SIGNAL
Multidisciplinary
Antimicrobial and antioxidant activities of Quillaja saponin and its impact in enhancing storage stability and microbiome modulation of refrigerated surimi gels
Comparative epidemiology and preparedness for African swine fever and porcine reproductive and respiratory syndrome in four major Asian swine industries
Frontiers in Veterinary Science
Thailand-affiliated authors
Thanh Che Nguyen · Roongtham Kedkovid · Roongroje Thanawongnuwech
Institutions
Chulalongkorn University
74IMPACT SIGNAL
Clinical Medicine
Pathways for glomerular macromolecule filtration: A mathematical model for transport across glomerular filtration surface, mesangium and shear-induced shunts
Mahidol University · The Royal College Of Anesthesiologists Of Thailand
74IMPACT SIGNAL
Clinical Medicine
Oxyresveratrol Suppresses EGF-Induced AKT Phosphorylation and Reduces Cellular Fitness While Promoting Apoptosis in EGFR–Wild-Type Non-Small Cell Lung Cancer Cells Under EGF Stimulation
Molecular Identification and Phylogenetic Position of Chaunocephalus ferox (Digenea: Echinostomatidae) from the Asian Openbill (Anastomus oscitans) in Thailand