Efficacy and safety of needle-free jet injection of self-crosslinking hyaluronic acid for facial fine wrinkles and skin texture: 12-week clinical outcomes in Asian women
Thirty Asian women aged 40-55 with Fitzpatrick III-IV skin received three needle-free jet sessions of self-crosslinking hyaluronic acid at four-week intervals. At week 12, 3D wrinkle and texture measures improved across malar and pericommissural regions; investigator severity fell from 7.28 to 4.32, and 60% reported moderate-to-marked improvement. Treatment reactions were mild and transient. The single-arm design cannot separate treatment effects from time or expectation.
Thai researchersAtchima Suwanchinda